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1.
Int J Mol Sci ; 21(19)2020 Sep 25.
Artigo em Inglês | MEDLINE | ID: mdl-32992921

RESUMO

Ultraviolet (UV) radiation from sunlight has various adverse effects; thus, UV blockage is recommended for preventing sunburn. Common sunscreen ingredients, such as nanosized titanium dioxide and zinc oxide, offer effective protection and enhance cosmetic appearance; however, health concerns have been raised regarding their photocatalytic activity, which generates reactive oxygen species under UV illumination. Silver nanoparticles (AgNPs) are known as safe materials for use in a wide spectrum of biomedical applications. In vitro studies have revealed that AgNPs may have a protective effect against UV irradiation, but the effects in animal studies remain unclear. The present study demonstrated that AgNPs effectively protect against UVB-induced skin damage both in cell cultures and mouse models. These results suggested that AgNPs are feasible and safe as sunscreen ingredients for protection against UVB-induced skin damage.


Assuntos
Nanopartículas Metálicas , Prata/farmacologia , Pele/efeitos dos fármacos , Pele/efeitos da radiação , Protetores Solares/farmacologia , Raios Ultravioleta/efeitos adversos , Animais , Células HaCaT , Humanos , Masculino , Camundongos , Camundongos Endogâmicos C57BL , Luz Solar/efeitos adversos
2.
Chem Commun (Camb) ; 51(71): 13662-5, 2015 Sep 14.
Artigo em Inglês | MEDLINE | ID: mdl-26226072

RESUMO

A thermally activated delayed fluorescent (TADF) emitter (DMAC-TRZ) was reported either as the emitting dopant in a host or as the non-doped (neat) emitting layer to achieve high EL EQEs of up to 26.5% and 20% in OLEDs, respectively.

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