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1.
Sci Total Environ ; 946: 174052, 2024 Oct 10.
Artigo em Inglês | MEDLINE | ID: mdl-38925377

RESUMO

To comply with environmental regulations, ship operators may adopt exhaust after-treatment devices such as scrubbers or selective catalytic reduction (SCR). Beyond gaseous emission control, these technologies impact the exhaust particles emitted from marine engines to the atmosphere. This study characterizes comprehensively the chemical composition and physical properties of exhaust aerosol particles upstream and downstream a hybrid scrubber operating in open loop mode on-board a modern cruise ship. The study considers two engines, one equipped with SCR and both with scrubber, during engine load conditions of 75 % and 40 %, and the influence of marine gas oil (MGO) use in addition to heavy fuel oil (HFO). At least 4 different particle types were observed in the exhaust based on transmission electron microscopy (TEM) studies both upstream and downstream scrubber, and both scrubber and SCR affected the particle number size distribution (PSD). The geometric mean diameter (GMD) of the particles increased over scrubber both due to removal of nucleation mode particles and particle growth in the scrubber. The scrubber effectively decreased particle number (PN) and, also, non-volatile particles, but the effect depended on particle size and no significant decrease was observed in number of particles above 50 nm, typically comprising black carbon (BC) and in the case of HFO combustion, also asymmetrical metal containing particles. In addition to PN, concentrations of PAH compounds were reduced in the scrubber. The results may be further utilized when including the exhaust aerosol characteristics from ships applying scrubbers to emission inventories, as well as climate and air quality models.

2.
Data Brief ; 26: 104374, 2019 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-31667216

RESUMO

This work includes raw and analyzed test data when using a recently developed fatigue test method for miniature laser welds in cobalt-chromium (CoCr) alloy joints [1]: 10.1016/j.jmbbm.2019.07.004. The automization of fatigue tests is crucial for saving costs and personnel resources and that is the reason why the atomization threshold and the resulting spectrum data related to CoCr welds are provided here. The finite element method based stress computation output is provided related to shearing-mode tests to support the dataset as a whole. In addition, the compositional data of the parent material and the laser weld are given.

3.
J Mech Behav Biomed Mater ; 99: 93-103, 2019 11.
Artigo em Inglês | MEDLINE | ID: mdl-31349149

RESUMO

Miniature laser welds with the root depth in the range of 50-300 µm represent air-tight joints between the components in medical devices, such as those in implants, growth rods, stents and various prostheses. The current work focuses on the development of a fatigue test specimen and procedure to determine fatigue lives of shear-loaded laser welds. A cobalt-chromium (CoCr) alloy is used as a benchmark case. S-N graphs, damage process, and fracture surfaces are studied by applying x-ray analysis, atomic force microscopy, and scanning electron microscopy both before and after the crack onset. A non-linear material model is fitted for the CoCr alloy to run finite element simulations of the damage and deformation. As a result, two tensile-loaded specimen designs are established and the performance is compared to that of a traditional torque-loaded specimen. The new generation specimens show less variation in the determined fatigue lives due to well-defined crack onset point and, therefore, precise weld seam load during the experiments. The fatigue damage concentrates to the welded material and the entire weld experiences fatigue prior to the final, fracture-governed failure phase. For the studied weld seams of hardened CoCr, a regression fatigue limit of 10.8-11.8 MPa, where the stress refers to the arithmetic average shear stress computed along the region dominated by shear loading, is determined.


Assuntos
Ligas de Cromo , Desenho de Equipamento , Lasers , Engenharia Biomédica , Força Compressiva , Análise de Elementos Finitos , Teste de Materiais , Microscopia de Força Atômica , Microscopia Eletrônica de Varredura , Modelos Teóricos , Pressão , Resistência ao Cisalhamento , Estresse Mecânico , Resistência à Tração , Torque
4.
Osteoarthritis Cartilage ; 27(8): 1235-1243, 2019 08.
Artigo em Inglês | MEDLINE | ID: mdl-31026649

RESUMO

OBJECTIVE: To investigate the feasibility of near-infrared (NIR) spectroscopy (NIRS) for evaluation of human articular cartilage biomechanical properties during arthroscopy. DESIGN: A novel arthroscopic NIRS probe designed in our research group was utilized by an experienced orthopedic surgeon to measure NIR spectra from articular cartilage of human cadaver knee joints (ex vivo, n = 18) at several measurement locations during an arthroscopic surgery. Osteochondral samples (n = 265) were extracted from the measurement sites for reference analysis. NIR spectra were remeasured in a controlled laboratory environment (in vitro), after which the corresponding cartilage thickness and biomechanical properties were determined. Hybrid multivariate regression models based on principal component analysis and linear mixed effects modeling (PCA-LME) were utilized to relate cartilage in vitro spectra and biomechanical properties, as well as to account for the spatial dependency. Additionally, a k-nearest neighbors (kNN) classifier was employed to reject outlying ex vivo NIR spectra resulting from a non-optimal probe-cartilage contact. Model performance was evaluated for both in vitro and ex vivo NIR spectra via Spearman's rank correlation (ρ) and the ratio of performance to interquartile range (RPIQ). RESULTS: Regression models accurately predicted cartilage thickness and biomechanical properties from in vitro NIR spectra (Model: 0.77 ≤ ρ ≤ 0.87, 2.03 ≤ RPIQ ≤ 3.0; Validation: 0.74 ≤ ρ ≤ 0.84, 1.87 ≤ RPIQ ≤ 2.90). When predicting cartilage properties from ex vivo NIR spectra (0.33 ≤ ρ ≤ 0.57 and 1.02 ≤ RPIQ ≤ 2.14), a kNN classifier enhanced the accuracy of predictions (0.52 ≤ ρ ≤ 0.87 and 1.06 ≤ RPIQ ≤ 1.88). CONCLUSION: Arthroscopic NIRS could substantially enhance identification of damaged cartilage by enabling quantitative evaluation of cartilage biomechanical properties. The results demonstrate the capacity of NIRS in clinical applications.


Assuntos
Artroscopia , Cartilagem Articular/diagnóstico por imagem , Articulação do Joelho/diagnóstico por imagem , Espectroscopia de Luz Próxima ao Infravermelho , Idoso , Cadáver , Cartilagem Articular/cirurgia , Estudos de Viabilidade , Feminino , Humanos , Articulação do Joelho/cirurgia , Masculino , Análise de Componente Principal , Análise de Regressão
5.
Clin Microbiol Infect ; 25(8): 1021-1025, 2019 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-30625412

RESUMO

OBJECTIVES: Antibiotics are used for various reasons before elective joint replacement surgery. The aim of this study was to investigate patients' use of oral antibiotics before joint replacement surgery and how this affects the risk for periprosthetic joint infection (PJI). METHODS: Patients having a primary hip or knee replacement in a tertiary care hospital between September 2002 and December 2013 were identified (n = 23 171). Information on oral antibiotic courses purchased 90 days preoperatively and patients' chronic diseases was gathered. Patients with a PJI in a 1-year follow-up period were identified. The association between antibiotic use and PJI was examined using a multivariable logistic regression model and propensity score matching. RESULTS: One hundred and fifty-eight (0.68%) cases of PJI were identified. In total, 4106 (18%) joint replacement operations were preceded by at least one course of antibiotics. The incidence of PJI for patients with preoperative use of oral antibiotics was 0.29% (12/4106), whereas for patients without antibiotic use it was 0.77% (146/19 065). A preoperative antibiotic course was associated with a reduced risk for subsequent PJI in the multivariable model (OR 0.40, 95% CI 0.22-0.73). Similar results were found in the propensity score matched material (OR 0.34, 95% CI 0.18-0.65). CONCLUSIONS: The use of oral antibiotics before elective joint replacement surgery is common and has a potential effect on the subsequent risk for PJI. Nevertheless, indiscriminate use of antibiotics before elective joint replacement surgery cannot be recommended, even though treatment of active infections remains an important way to prevent surgical site infections.


Assuntos
Antibacterianos/administração & dosagem , Antibioticoprofilaxia/estatística & dados numéricos , Artroplastia de Quadril/efeitos adversos , Artroplastia do Joelho/efeitos adversos , Infecções Relacionadas à Prótese/prevenção & controle , Infecção da Ferida Cirúrgica/prevenção & controle , Administração Oral , Idoso , Feminino , Seguimentos , Humanos , Modelos Logísticos , Masculino , Pessoa de Meia-Idade , Pontuação de Propensão , Infecções Relacionadas à Prótese/microbiologia , Fatores de Risco , Infecção da Ferida Cirúrgica/microbiologia
6.
Clin Microbiol Infect ; 24(4): 376-380, 2018 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-28760710

RESUMO

OBJECTIVES: Patients who undergo elective joint replacement are traditionally screened and treated for preoperative bacteriuria to prevent periprosthetic joint infection (PJI). More recently, this practice has been questioned. The purpose of this study was to determine whether preoperative bacteriuria is associated with an increased risk of PJI. METHODS: Patients who had undergone a primary hip or knee replacement in a tertiary care hospital between September 2002 and December 2013 were identified from the hospital database (23 171 joint replacements, 10 200 hips, and 12 971 knees). The results of urine cultures taken within 90 days before the operation were obtained. Patients with subsequent PJI or superficial wound infection in a 1-year follow-up period were identified based on prospective infection surveillance. The association between bacteriuria and PJI was examined using a multivariable logistic regression model that included information on the operated joint, age, gender and the patients' chronic diseases. RESULTS: The incidence of PJI was 0.68% (n = 158). Preoperative bacteriuria was not associated with an increased risk of PJI either in the univariate (0.51% versus 0.71%, OR 0.72, 95% CI 0.34-1.54) or in the multivariable (OR 0.82, 95% CI 0.38-1.77) analysis. There were no cases where PJI was caused by a pathogen identified in the preoperative urine culture. Results were similar for superficial infections. CONCLUSIONS: There was no association between preoperative bacteriuria and postoperative surgical site infection. Based on these results, it seems that the preoperative screening and treatment of asymptomatic bacteriuria is not required.


Assuntos
Artrite/epidemiologia , Artroplastia de Quadril , Artroplastia do Joelho , Bacteriúria/complicações , Infecções Relacionadas à Prótese/epidemiologia , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Medição de Risco , Centros de Atenção Terciária , Adulto Jovem
7.
Opt Express ; 10(1): 24-34, 2002 Jan 14.
Artigo em Inglês | MEDLINE | ID: mdl-19424326

RESUMO

Formulation of the Fourier modal method for multilevel structures with spatially adaptive resolution is presented, using a slightly reformulated representation for the spatial coordinates. Projections to Fourier base in boundary value problem are used allowing extensions to multilayer profiles with differently placed transitions. We evade the eigenvalue problem in homogeneous regions demanded in the original formulation of the Fourier modal method with adaptive spatial resolution.

8.
Appl Opt ; 40(14): 2239-46, 2001 May 10.
Artigo em Inglês | MEDLINE | ID: mdl-18357231

RESUMO

A LCD backlighting device that uses a diffractive light extractor has been developed for applications in which pointlike light sources are employed. The novel system eliminates the images of light sources, which appear as bright lines emanating from each source in the conventional diffractive approach. In addition, the system illuminates the LCD uniformly: Modulation of the diffractive structure as a function of position is used to control the output field of this extended planar light source.

9.
Appl Opt ; 36(10): 2034-41, 1997 Apr 01.
Artigo em Inglês | MEDLINE | ID: mdl-18253170

RESUMO

We address the problem of shaping the radiant intensity distribution of a highly nonparaxial coherent field by means of a diffractive element located in the plane of the beam waist. To be capable of wide-angle energy redistribution the element must necessarily contain wavelength-scale transverse features, and consequently it must be designed on the basis of rigorous diffraction theory. We consider, in particular, wide-angle Gaussian to flat-top beam shaping in one dimension. Scalar designs are provided and their validity is evaluated by rigorous diffraction theory, which is also used for optimization deep inside the nonparaxial domain, where the scalar designs fail. Experimental verification is provided by means of electron-beam lithography.

10.
Opt Lett ; 21(7): 513-5, 1996 Apr 01.
Artigo em Inglês | MEDLINE | ID: mdl-19865456

RESUMO

We present what is to our knowledge the first experimental observation of controlled intensity f luctuations of Fresnel holograms of 8 microm x 8 microm pixel size by using a function for calculation of optical phase errors from the pixel area of an aperture of synthetic Fresnel holograms derived without approximation.

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