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Microbiol Spectr ; 11(6): e0147123, 2023 Dec 12.
Artigo em Inglês | MEDLINE | ID: mdl-37905800

RESUMO

IMPORTANCE: Of 123 identified isolates from the fruit surface, C. tropicalis was the most frequently found species, followed by Meyerozyma caribbica and Candida krusei. All three fluconazole-resistant C. tropicalis were non-susceptible to voriconazole and belonged to the same predominant genotype of azole-resistant C. tropicalis causing candidemia in patients in Taiwan. Our findings provide evidence that fruit should be washed before eaten not only to remove chemicals but also potential drug-resistant pathogenic microbes, especially for immunocompromised individuals. To keep precious treatment options in patients, we not only continuously implement antimicrobial stewardship in hospitals but also reducing/stopping the use of agricultural fungicide classes used in human medicine.


Assuntos
Antifúngicos , Candida tropicalis , Humanos , Antifúngicos/farmacologia , Antifúngicos/uso terapêutico , Candida tropicalis/genética , Frutas , Fluconazol/farmacologia , Voriconazol , Testes de Sensibilidade Microbiana , Farmacorresistência Fúngica
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