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1.
Sci Rep ; 12(1): 12314, 2022 Jul 19.
Artigo em Inglês | MEDLINE | ID: mdl-35853924

RESUMO

This paper investigates the regularity of microstructural evolution of Shenzhen granite residual soil in an attempt to determine its macrostructural deformation characteristics. The pore distribution and microstructure characteristics of granite residual soil are examined experimentally under different consolidation stresses, coupled with mercury injection tests and scanning electron microscopy. It is found that a microstructure exists in the granite residual soil and that the structural characteristics of granite residual soil in Shenzhen. The calculated pre-consolidation stress and structural yield strength of the granite residual soil are similar, indicating a phenomenon that resembles over-consolidation in the granite residual soil. This is fundamentally different from the mechanism of conventional over-consolidation in soil. It is also found that the relationship between the increment of mercury in soil samples and the stress of the mercury under different consolidation stresses is mainly trimodal. The significance of the research presented in this paper lies in the development of a clear understanding of the influence of the microstructure characteristics of granite residual soil on its macrostructural deformation, thereby providing a theoretical basis for engineering applications involving granite residual soil and the analysis of foundation deformation.

2.
Nat Prod Res ; 32(6): 662-667, 2018 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-28602098

RESUMO

One new alkaloid, named as acremolin C (1), was isolated from static culture of Antarctic fungus, Aspergillus sydowii SP-1, in an investigation of the antimicrobial constituents of this Antarctic microorganism, and its structure was determined by spectroscopic methods. Additionally, four known compounds, cyclo-(L-Trp-L-Phe) (2), 4-hydroxyphenylacetic acid (3), (7S)-(+)-hydroxysydonic acid (4) and (7S, 11S)-(+)-12-hydroxysydonic acid (5), were isolated and identified. Biological studies disclosed that compounds 2, 4 and 5 showed moderate inhibitions against methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-resistant Staphylococcus epidermidis (MRSE) as comparing to tigecycline, while compound 1 displayed weak inhibition activities against MRSA and MRSE.


Assuntos
Alcaloides/química , Alcaloides/farmacologia , Antibacterianos/química , Antibacterianos/farmacologia , Aspergillus/química , Regiões Antárticas , Staphylococcus aureus Resistente à Meticilina/efeitos dos fármacos , Testes de Sensibilidade Microbiana , Estrutura Molecular , Fenilacetatos/análise , Fenilacetatos/farmacologia , Sesquiterpenos/análise , Sesquiterpenos/farmacologia , Staphylococcus epidermidis/efeitos dos fármacos
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