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1.
Int J Surg Case Rep ; 5(10): 774-8, 2014.
Artigo em Inglês | MEDLINE | ID: mdl-25262323

RESUMO

INTRODUCTION: Melanoma shows a particular predilection in involving small intestine both in a single site and in multiple localization and acute or chronic gastrointestinal bleedings are often the first sign of tumour. PRESENTATION OF CASE: We report two cases of GI metastases of malignant melanoma, one presented with only a big mass that cause intestinal obstruction and the other with a tumour spread throughout the small intestine that produce enterorrhagia. DISCUSSION: Diagnosis and follow-up are very difficult: CT scan, PET-CT scan and capsule endoscopy should be complementary for the assessment of patients with GI symptoms and melanoma history. CONCLUSION: What is the role of surgery? Several studies suggest metastasectomy to achieve both R0 results and palliative resolutions of acute symptoms, such as obstruction, pain, and bleeding.

2.
Updates Surg ; 64(2): 157-60, 2012 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-21660615

RESUMO

Peritoneal mesothelioma is a rare form of malignant mesothelioma, making up <30% of diagnosed mesothelioma cases. Because of a lack of specific symptoms (abdominal pain, abdominal swelling), normally it is diagnosed in advanced stages, sometimes in a surgical emergency (intestinal obstruction, severe ascites) and occasionally during image procedures or laparoscopy which can show a mass developing from peritoneal mesothelium surfaces, or an accumulation of small irregularities that may be tumors or plaques. The reported case refers to a particular localization of a peritoneal mesothelioma, the spleen, discovered only after a splenectomy, due to the clinical and radiological suspect of a rupture.


Assuntos
Laparoscopia , Mesotelioma/cirurgia , Recidiva Local de Neoplasia , Neoplasias Peritoneais/cirurgia , Esplenectomia , Neoplasias Esplênicas/cirurgia , Protocolos de Quimioterapia Combinada Antineoplásica/uso terapêutico , Cisplatino/administração & dosagem , Desoxicitidina/administração & dosagem , Desoxicitidina/análogos & derivados , Humanos , Masculino , Mesotelioma/diagnóstico por imagem , Mesotelioma/tratamento farmacológico , Mesotelioma/secundário , Pessoa de Meia-Idade , Gradação de Tumores , Neoplasias Peritoneais/diagnóstico por imagem , Neoplasias Peritoneais/tratamento farmacológico , Neoplasias Peritoneais/patologia , Radiografia , Esplenectomia/métodos , Neoplasias Esplênicas/diagnóstico por imagem , Neoplasias Esplênicas/tratamento farmacológico , Neoplasias Esplênicas/secundário , Fatores de Tempo , Falha de Tratamento , Gencitabina
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