RESUMO
In Russia, both alveolar and cystic echinococcoses are endemic. This study aimed to identify the aetiological agents of the diseases and to investigate the distribution of each Echinococcus species in Russia. A total of 75 Echinococcus specimens were collected from 14 host species from 2010 to 2012. Based on the mitochondrial DNA sequences, they were identified as Echinococcus granulosus sensu stricto (s.s.), E. canadensis and E. multilocularis. E. granulosus s.s. was confirmed in the European Russia and the Altai region. Three genotypes, G6, G8 and G10 of E. canadensis were detected in Yakutia. G6 was also found in the Altai region. Four genotypes of E. multilocularis were confirmed; the Asian genotype in the western Siberia and the European Russia, the Mongolian genotype in an island of Baikal Lake and the Altai Republic, the European genotype from a captive monkey in Moscow Zoo and the North American genotype in Yakutia. The present distributional record will become a basis of public health to control echinococcoses in Russia. The rich genetic diversity demonstrates the importance of Russia in investigating the evolutionary history of the genus Echinococcus.
Assuntos
DNA de Helmintos/genética , DNA Mitocondrial/genética , Equinococose/parasitologia , Echinococcus/genética , Complexo IV da Cadeia de Transporte de Elétrons/genética , Variação Genética , Filogenia , Animais , DNA de Helmintos/classificação , DNA Mitocondrial/classificação , Equinococose/classificação , Equinococose/diagnóstico , Equinococose/epidemiologia , Echinococcus/classificação , Complexo IV da Cadeia de Transporte de Elétrons/classificação , Genoma Mitocondrial , Genótipo , Especificidade de Hospedeiro , Humanos , Epidemiologia Molecular , Federação Russa/epidemiologia , Especificidade da EspécieRESUMO
Mitochondrial haplotypes were determined for Echinococcus species infecting individuals diagnosed with alveolar echinococcosis (AE) and cystic echinococcosis (CE) at Altai State Medical University Hospital in Barnaul, Russia during 2008 to 2011. The nucleotide sequence of the mitochondrial cytochrome c oxidase subunit 1 (cox1) gene was determined for 31 of 34 AE and 8 of 12 CE cases. All of the AE cases were confirmed to be caused by Asian type Echinococcus multilocularis, while CE cases were caused by Echinococcus granulosus sensu stricto (genotype G1) and Echinococcus canadensis (genotype G6).