RESUMO
The relationship between changes in phospholipids of red blood cells and frontal cortex during repeated 5, 10, 15, 20, 30 and 45 days of immobilization (for 2 hours a day) was studied on non-linear stress-resistant and stress-unstable white male rats. We suggested a regression equation that can be used for in vivo assessment of brain lipid composition under influence of the stress.
Assuntos
Membrana Celular/química , Eritrócitos/química , Lobo Frontal/química , Fosfolipídeos/análise , Estresse Fisiológico , Animais , Lobo Frontal/fisiologia , Imobilização , Masculino , Fosfolipídeos/fisiologia , Ratos , Análise de Regressão , Especificidade da EspécieRESUMO
In this work, we investigated surface active properties and biochemical composition of pulmonary surfactant under emotional stress in condition of neuropeptides pool exhaustion in capsaicin-sensitive afferents of the vagus nerve. It is shown that stress is accompanied by decrease of lung surface active properties and increase of total phospholipids content as result of phosphatidylcholine and lysophospholipid fraction rise. After capsaicin application on the cervical part of the right vagus nerve stress-induced alterations in ipsilateral lung become less considerable, whereas all spectra of changes in contralateral lung is remained.