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J Natl Compr Canc Netw ; 10(7): 821-9, 2012 Jul 01.
Artigo em Inglês | MEDLINE | ID: mdl-22773798

RESUMO

These NCCN Guidelines Insights highlight the important updates/changes specific to the management of metastatic breast cancer in the 2012 version of the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Breast Cancer. These changes/updates include the issue of retesting of biomarkers (estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2) on recurrent disease, new information regarding first-line combination endocrine therapy for metastatic disease, a new section on monitoring of patients with metastatic disease, and new information on endocrine therapy combined with an mTOR inhibitor as a subsequent therapeutic option.


Assuntos
Antineoplásicos Hormonais/uso terapêutico , Neoplasias da Mama/tratamento farmacológico , Neoplasias da Mama/patologia , Inibidores de Proteínas Quinases/uso terapêutico , Biomarcadores Tumorais , Neoplasias da Mama/metabolismo , Feminino , Humanos , Metástase Neoplásica , Serina-Treonina Quinases TOR/antagonistas & inibidores
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