[Hyperbaric oxygenation in acute compression-dislocation syndrome (experimental-morphological study)]. / Giperbaricheskaia oksiganatsiia pri ostrom kompressionno- dislokatsionnom sindrome (éksperimental'no-morfologicheskoe issledovanie).

Acute compression dislocation syndrome was reproduced in rabbits by means of epidural brain compression with a balloon. After elimination of brain compression the main group were treated by HBO whereas the control group did not receive HBO. The use of HBO resulted in a decrease of the lethality in hyperextension manifestations. Using the total water measurement in the brain the main group was discovered to have a decrease of brain edema at different times, associated with compression and eliminated compression thereof. Microscopy revealed a reduction of pericellular, perivascular and subependymal edema as well as of edema of vascular plexus and venous brain plethora under the influence of HBO.

[Therapeutic effect of hyperbaric oxygenation in various manifestations of acute renal-hepatic insufficiency]. / Lechebnyi éffekt giperbaricheskoi oksigenatsii pri nekotorykh proiavleniiakh ostroi pochechno-pechenochnoi nedostatochnosti.

The studies of the clinical pattern, chest X-ray films, central hemodynamic parameters, hepatic blood flow and respiratory functions in patients with acute renal-hepatic failure due to various exo- and endotoxemias have shown that hyperbaric oxygenation decreases the degree of first to second stage pulmonary hyperhydration and hepatic encephalopathy. Parallel correction of the cardiac output, recovery of the decreased hepatic blood flow and normalization of respiratory function have been observed.

[The effect of hyperbaric oxygenation on the course and outcome of acute dislocation syndrome in uncorrected and corrected experimental compression of the brain]. / Vliianie giperbaricheskoi oksigenatsii na techenie i iskhod ostrogo dislokatsionnogo sindroma pri neustranennoi i ustranennoi kompressii mozga v éksperimente.

Acute compression-dislocation syndrome of a severe degree was reproduced in rabbits by dosed compression of the brain with an epidurally situated balloon. Animals of the main group were treated by HBO in persisting compression of the brain (series I) and after its correction (series II). Animals of the control group were not treated. HBO had no influence on mortality in series I, a tendency towards reduction of the animals's survival period under the effect of hyperoxia was noted. In series II HBO led to reduction of mortality among rabbits with the severest manifestations of the syndrome and a more frequent and full recovery of animals who survived.

[Effects of hyperbaric oxygenation in acute compression-dislocation syndrome in experimental animals]. / Vliianie na ostryi kompresionno-dislokatsionnyi sindrom giperbaricheskoi oksigenatsii v éksperimente.

A model of the acute compression dislocation syndrome of grave degree was designed by means of local compression of the parietotemporal area of rabbit brain. A study was made of the effect produced by hyperbaric oxygenation (HBO) on the syndrome after compression elimination. HBO has been noted to decrease the lethality, primarily among animals with the gravest manifestations of the syndrome, to bring about frequent and more full-value recovery of the survived animals, and an insignificant lowering of brain edema.

[Effect of hyperbaric oxygenation on the dynamics of the alcohol abstinence syndrome]. / Vozdeistvie giperbaricheskoi oksigenatsii na dinamiku alkogol'nogo abstinentnogo sindroma.

Hyperbaric oxygenation (HBO) was used in 40 patients with the alcoholic abstinence syndrome (AAS), Stages I and II severity, either as a component of multiple modality (in combination with drugs) or the only treatment. The results of clinico-psychoneurological examination have demonstrated that the use of HBO in the treatment of patients with the AAS significantly accelerates the time of AAS elimination as compared with the control group receiving drug therapy alone. An HBO session markedly reduces psychoneurological and somatovegetative symptomatology which is attended by a reduction in systolic blood pressure and in the heart rate. Analysis of the electrocardiographic findings obtained in patients with alcoholic involvement of the heart at the height of the AAS has shown that HBO helps improve the myocardial status. The best results are achieved in patients with Stage II AAS when HBO therapy (two sessions daily) is started at early stages of the syndrome.

[Clinical effectiveness of hyperbaric oxygenation in the combined treatment of patients with schizophrenia]. / Klinicheskaia éffektivnost' giperbaricheskoi oksigenatsii v kompleksnom lechenii bol'nykh shizofreniei.

Hyperbaric oxygenation (HBO) was employed in 50 schizophrenic patients showing resistance to the conducted drug therapy. Thirty-two patients had shift-like and 18, sluggish, moderately and slowly progressive forms of schizophrenia. HBO treatment was always combined with psychopharmacotherapy. The results of the study have shown the advisability of inclusion of HBO into the multiple-modality treatment of patients with asthenic and apathetic depressions encountered during a shift-like or sluggish, schizophrenia with hysteric-hypochondriac disturbances and obsessions. The maximum therapeutic effect was observed after 10-12 sessions of HBO.

[Effect of hyperbaric oxygenation on total water content of brain tissue in experimental traumatic edema of the brain]. / Vliianie giperbaricheskoi oksigenatsii na soderzhanie obshchei vody v mozgovoi tkani pri éksperimental'nom travmaticheskom oteke mozga.

Experiments were conducted on 30 rabbits with dosed injury inflicted on the brain; 15 animals were treated by means of hyperbaric oxygenation (HBO), the other 15 animals were not given treatment. The amount of total water in the brain tissue (separately in the grey and white matter) in various areas was determined by dessicating samples to constant weight. A significant reduction in the amount of tissue water in the brain in its traumatic edema occurred under the effect of HBO; a course of 10 sessions proved to be more effective than a course of 6 sessions.

[Hyperbaric oxygenation in ruptured cerebral aneurysms during the postoperative period]. / Giperbaricheskaia oksigenatsiia pri razorvavshikhsia anevrizmakh golovnogo mozga v posleoperatsionnom periode.

The OKA-MT pressure chamber was used. The course consisted of 6-15 sessions at a pressure of 1.6-2.0 at. abs. Hyperbaric oxygenation (HBO) was included in the complex of therapeutic measures applied in the postoperative period in patients with ruptured aneurysms of the cerebral vessels. From comparison of the course of the disease in 47 patients treated by HBO with that in 30 patients not subjected to HBO (control group) the authors conclude that the inclusion of HBO in the complex of measures applied after operations on the cerebral vessels for ruptured aneurysms has a positive effect on the course of the disease: the grave condition is less prolonged; the duration of the meningeal syndrome, headache, and temperature reaction is shorter by 6 days than in the control group; the number of patients with a good result of treatment increases by 18%; mental disorders in the absence of hematoma of the frontal area are prevented; the frequency of suppurations of the postoperative wound diminishes.

[Effect of hyperbaric oxygenation on the course of experimental brain edema]. / Vliianie giperbaricheskoi oksigenatsii na techenie oteka mozga v éksperimente.

The authors studied experimental brain edema and morphological changes in the cerebral tissue in 2 groups of animals: the test group receiving hyperbaric oxygenation (HBO) and the control group. The test animals showed a more favourable course of brain injury. Microscopic examination revealed a lesser degree of brain edema and intensification of reparative processes in the cerebral tissues of animals receiving HBO.

[Effect of hyperbaric oxygenation on the water content of brain tissue in experimental toxic cerebral edema]. / Vliianie giperbaricheskoi oksigenatsii na soderzhanie vody v mozgovoi tkani pri toksicheskom oteke mozga v éksperimente.

A study on rabbits with a toxic edema of the brain showed a significant decrease in the tissue water in the grey and white matter under the impact of hyperbaric oxygenation.

[Effectiveness of hyperbaric oxygenation after operations for acute intestinal obstruction]. / Effektivnost' giperbaricheskoi oksigenatsii posle operatsii po povodu ostoi kishechnoi neprokhodimosti.

Positive effects of HBO sessions on indices of central hemodynamics is shown in 34 patients with different forms of acute intestinal obstruction.

[Hyperbaric oxygenation in the prevention of mental disorders in patients during the acute period of severe craniocerebral injuries]. / Giperbaricheskaia oksigenatsiia v profilaktike psikhicheskikh narushenii u bol'nykh v ostrom periode tiazheloi cherepno-mozgovoi travmy.

On the basis of a comparative analysis of the incidence of psychic disturbances seen in two groups of patients with craniocerebral trauma (subjects receiving HBO treatment and those without it), it is concluded that HBO is effective in preventing trauma-associated psychoses. The effect of HBO on the external respiration and central hemodynamics was also examined. The obtained results formed the basis for discussing possible pathogenetic mechanisms of hyperbaric oxygen action in this pathology.

[Hyperbaric oxygenation in paroxysmal and extrasystolic disorders of cardiac rhythm]. / Giperbaricheskaia oksigenatsiia pri paroksizmal'nykh i ékstrasistolicheskikh narusheniiakh serdechnogo ritma.

Hyperbaric oxygenation (HBO) was used as part of combined treatment in 102 patients with frequent paroxysms of atrial fibrillation and supraventricular tachycardia, and extrasystoles associated with coronary disease in 74 and neurogenic disturbances in 28 patients. HBO was indicated where anti-arrhythmic drugs had proved inefficient. Electrocardiographic, hemodynamic (rheographic), spirographic parameters and blood catecholamines were examined. Extrasystoles became less frequent or disappeared altogether for varying intervals in 75% of coronary patients, the duration of disappearance depending on the duration of their former presence. Stable disappearance of extrasystoles for 6-12 months was noted in 50% of coronary patients with less than two years' existence of extrasystole. In atrial fibrillation paroxysms due to coronary disease, HBO-incorporating combined treatment eliminated paroxysms for 4 to 10 months. In addition to normalizing cardiac rhythm, HBO increased formerly low cardiac output, reduced hyperventilation, eliminated respiratory arrhythmias and brought down blood catecholamine levels.

[Effect of hyperbaric oxygenation on the clinical course and complications of the acute period of ischemic strokes]. / Vliianie giperbaricheskoi oksigenatsii na klinicheskoe techenie i oslozhneniia ostrogo perioda ishemicheskogo insul'ta.

Hyperbaric oxygenation (HBO) was included in the therapeutic complex for 124 patients in the acute stage of ischemic stroke. The effect of HBO on the clinical course was appraised by comparing the dynamics of changes in the clinical symptoms and the frequency of complications in patients exposed to HBO with those in the control group (patients not exposed to HBO). It was established that the depth of unconsciousness and the motor and aphasic disorders decreased during a HBO session, but the effect was usually short-lived. Aggravation of the patients' condition in the first week of the disease, evidently caused by increase of cerebral edema, occurred much less frequently when HBO was included in the complex of therapeutic measures. The number of patients with regression of the neurological symptoms was practically the same with and without the use of HBO, but the regression of the neurological defects was most evident in patients exposed to HBO. HBO prevents the development of recurrent cerebral circulatory disorders in the acute stage of ischemic stroke and reduces the incidence of some complications in this period (pneumonia, pulmonary edema, thromboembolism of the pulmonary artery, etc.).