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Phys Med Biol ; 62(4): 1310-1326, 2017 02 21.
Artigo em Inglês | MEDLINE | ID: mdl-28114125

RESUMO

Recently, the use of 4He particles in cancer radiotherapy has been reconsidered as they potentially represent a good compromise between protons and 12C ions. The first step to achieve this goal is the development of a dedicated treatment planning system, for which basic physics information such as the characterization of the beam lateral scattering and fragmentation cross sections are required. In the present work, the attenuation of 4He primary particles and the build-up of secondary charged fragments at various depths in water and polymethyl methacrylate were investigated experimentally for 120 and 200 MeV u-1 beams delivered by the synchrotron at the Heidelberg Ion-Beam Therapy Center, Heidelberg. Species and isotope identification was accomplished combining energy loss and time-of-flight measurements. Differential yields and energy spectra of all fragments types were recorded between 0° and 20° with respect to the primary beam direction.


Assuntos
Hélio/química , Hélio/uso terapêutico , Polimetil Metacrilato/química , Planejamento da Radioterapia Assistida por Computador/métodos , Síncrotrons/instrumentação , Água/química , Humanos , Eficiência Biológica Relativa
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