1.
Antioxidants (Basel)
; 13(1)2023 Dec 28.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38247546
RESUMO
In the original publication [...].
2.
Antioxidants (Basel)
; 10(9)2021 Sep 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34573102
RESUMO
In order to study how polyphenols and vitamin C (vitC) together affect protein aggregation to amyloid fibrils, we performed similar in vitro studies as before using stefin B as a model and a potentially amyloid-forming protein (it aggregates upon overexpression, under stressful conditions and some progressive myoclonus epilepsy of tape 1-EPM1-missense mutations). In addition to the chosen polyphenol, this time, we added a proven antioxidant concentration of 0.5 mM vitC into the fibrillation mixture and varied concentrations of resveratrol, quercetin, and curcumin. Synergy with vitC was observed with curcumin and quercetin.