Template subtraction based methods for non-invasive fetal electrocardiography extraction.

Assessment of fetal heart rate (fHR) through non-invasive fetal electrocardiogram (fECG) is challenging task. This study compares the performance of five template subtraction (TS) methods on Labor (12 5-min recordings) and Pregnancy datasets (10 20-min recordings). The methods include TS without adaptation, TS using singular value decomposition (TS[Formula: see text]), TS using linear prediction (TS[Formula: see text]), TS using scaling factor (TS[Formula: see text]), and sequential analysis (SA). The influence of the chosen maternal wavelet for the continuous wavelet transform (CWT) detector is also compared. The F1 score was used to measure performance. Each recording in both datasets consisted of four signals, resulting in a total comparison of 88 signals for the TS-based methods. The study reported the following results: F1 = 95.71% with TS, F1 = 95.93% with TS[Formula: see text], F1 = 95.30% with TS[Formula: see text], F1 = 95.82% with TS[Formula: see text], and F1 = 95.99% with SA. The study identified gaus3 as the suitable maternal wavelet for fetal R-peak detection using the CWT detector. Furthermore, the study classified signals from the tested datasets into categories of high, medium, and low quality, providing valuable insights for subsequent fECG signal extraction. This research contributes to advancing the understanding of non-invasive fECG signal processing and lays the groundwork for improving fetal monitoring in clinical settings.

Instrumentation for Verification of Shunt Active Power Filter Algorithms.

This article presents a comprehensive system for testing and verifying shunt active power filter control methods. The aim of this experimental platform is to provide tools to a user to objectively compare the individual control methods. The functionality of the system was verified on a hardware platform using least mean squares and recursive least squares algorithms. In the experiments, an average relative suppression of the total harmonic distortion of 22% was achieved. This article describes the principle of the shunt active power filter, the used experimental platform of the controlled current injection source, its control system based on virtual instrumentation and control software and ends with experimental verification. The discussion of the paper outlines the extension of the experimental platform with the cRIO RTOS control system to reduce the latency of reference current generation and further planned research including motivation.

Novel phonocardiography system for heartbeat detection from various locations.

The paper presents evaluation of the proposed phonocardiography (PCG) measurement system designed primarily for heartbeat detection to estimate heart rate (HR). Typically, HR estimation is performed using electrocardiography (ECG) or pulse wave as one of the fundamental diagnostic methodologies for assessing cardiac function. The system includes novel both sensory part and data processing procedure, which is based on signal preprocessing using Wavelet Transform (WT) and Shannon energy computation and heart sounds classification using K-means. Due to the lack of standardization in the placement of PCG sensors, the study focuses on evaluating the signal quality obtained from 7 different sensor locations on the subject's chest and investigates which locations are most suitable for recording heart sounds. The suitability of sensor localization was examined in 27 subjects by detecting the first two heart sounds (S1, S2). The HR detection sensitivity related to reference ECG from all sensor positions reached values over 88.9 and 77.4% in detection of S1 and S2, respectively. The placement in the middle of sternum showed the higher signal quality with median of the proper S1 and S2 detection sensitivity of 98.5 and 97.5%, respectively.

Independent component analysis algorithms for non-invasive fetal electrocardiography.

The independent component analysis (ICA) based methods are among the most prevalent techniques used for non-invasive fetal electrocardiogram (NI-fECG) processing. Often, these methods are combined with other methods, such adaptive algorithms. However, there are many variants of the ICA methods and it is not clear which one is the most suitable for this task. The goal of this study is to test and objectively evaluate 11 variants of ICA methods combined with an adaptive fast transversal filter (FTF) for the purpose of extracting the NI-fECG. The methods were tested on two datasets, Labour dataset and Pregnancy dataset, which contained real records obtained during clinical practice. The efficiency of the methods was evaluated from the perspective of determining the accuracy of detection of QRS complexes through the parameters of accuracy (ACC), sensitivity (SE), positive predictive value (PPV), and harmonic mean between SE and PPV (F1). The best results were achieved with a combination of FastICA and FTF, which yielded mean values of ACC = 83.72%, SE = 92.13%, PPV = 90.16%, and F1 = 91.14%. Time of calculation was also taken into consideration in the methods. Although FastICA was ranked to be the sixth fastest with its mean computation time of 0.452 s, it had the best ratio of performance and speed. The combination of FastICA and adaptive FTF filter turned out to be very promising. In addition, such device would require signals acquired from the abdominal area only; no need to acquire reference signal from the mother's chest.

Implementation of artificial intelligence and machine learning-based methods in brain-computer interaction.

Brain-computer interfaces are used for direct two-way communication between the human brain and the computer. Brain signals contain valuable information about the mental state and brain activity of the examined subject. However, due to their non-stationarity and susceptibility to various types of interference, their processing, analysis and interpretation are challenging. For these reasons, the research in the field of brain-computer interfaces is focused on the implementation of artificial intelligence, especially in five main areas: calibration, noise suppression, communication, mental condition estimation, and motor imagery. The use of algorithms based on artificial intelligence and machine learning has proven to be very promising in these application domains, especially due to their ability to predict and learn from previous experience. Therefore, their implementation within medical technologies can contribute to more accurate information about the mental state of subjects, alleviate the consequences of serious diseases or improve the quality of life of disabled patients.

Pregnancy in the time of COVID-19: towards Fetal monitoring 4.0.

On the outbreak of the global COVID-19 pandemic, high-risk and vulnerable groups in the population were at particular risk of severe disease progression. Pregnant women were one of these groups. The infectious disease endangered not only the physical health of pregnant women, but also their mental well-being. Improving the mental health of pregnant women and reducing their risk of an infectious disease could be achieved by using remote home monitoring solutions. These would allow the health of the mother and fetus to be monitored from the comfort of their home, a reduction in the number of physical visits to the doctor and thereby eliminate the need for the mother to venture into high-risk public places. The most commonly used technique in clinical practice, cardiotocography, suffers from low specificity and requires skilled personnel for the examination. For that and due to the intermittent and active nature of its measurements, it is inappropriate for continuous home monitoring. The pandemic has demonstrated that the future lies in accurate remote monitoring and it is therefore vital to search for an option for fetal monitoring based on state-of-the-art technology that would provide a safe, accurate, and reliable information regarding fetal and maternal health state. In this paper, we thus provide a technical and critical review of the latest literature and on this topic to provide the readers the insights to the applications and future directions in fetal monitoring. We extensively discuss the remaining challenges and obstacles in future research and in developing the fetal monitoring in the new era of Fetal monitoring 4.0, based on the pillars of Healthcare 4.0.

A Review of Recent Advances and Future Developments in Fetal Phonocardiography.

Fetal phonocardiography (fPCG) is receiving attention as it is a promising method for continuous fetal monitoring due to its non-invasive and passive nature. However, it suffers from the interference from various sources, overlapping the desired signal in the time and frequency domains. This paper introduces the state-of-the-art methods used for fPCG signal extraction and processing, as well as means of detection and classification of various features defining fetal health state. It also provides an extensive summary of remaining challenges, along with the practical insights and suggestions for the future research directions.

Nature inspired method for noninvasive fetal ECG extraction.

This paper introduces a novel algorithm for effective and accurate extraction of non-invasive fetal electrocardiogram (NI-fECG). In NI-fECG based monitoring, the useful signal is measured along with other signals generated by the pregnant women's body, especially maternal electrocardiogram (mECG). These signals are more distinct in magnitude and overlap in time and frequency domains, making the fECG extraction extremely challenging. The proposed extraction method combines the Grey wolf algorithm (GWO) with sequential analysis (SA). This innovative combination, forming the GWO-SA method, optimises the parameters required to create a template that matches the mECG, which leads to an accurate elimination of the said signal from the input composite signal. The extraction system was tested on two databases consisting of real signals, namely, Labour and Pregnancy. The databases used to test the algorithms are available on a server at the generalist repositories (figshare) integrated with Matonia et al. (Sci Data 7(1):1-14, 2020). The results show that the proposed method extracts the fetal ECG signal with an outstanding efficacy. The efficacy of the results was evaluated based on accurate detection of the fQRS complexes. The parameters used to evaluate are as follows: accuracy (ACC), sensitivity (SE), positive predictive value (PPV), and F1 score. Due to the stochastic nature of the GWO algorithm, ten individual runs were performed for each record in the two databases to assure stability as well as repeatability. Using these parameters, for the Labour dataset, we achieved an average ACC of 94.60%, F1 of 96.82%, SE of 97.49%, and PPV of 98.96%. For the Pregnancy database, we achieved an average ACC of 95.66%, F1 of 97.44%, SE of 98.07%, and PPV of 97.44%. The obtained results show that the fHR related parameters were determined accurately for most of the records, outperforming the other state-of-the-art approaches. The poorer quality of certain signals have caused deviation from the estimated fHR for certain records in the databases. The proposed algorithm is compared with certain well established algorithms, and has proven to be accurate in its fECG extractions.

Review of Fundamental Active Current Extraction Techniques for SAPF.

The field of advanced digital signal processing methods is one of the fastest developing scientific and technical disciplines, and is important in the field of Shunt Active Power Filter control methods. Shunt active power filters are highly desirable to minimize losses due to the increase in the number of nonlinear loads (deformed power). Currently, there is rapid development in new adaptive, non-adaptive, and especially hybrid methods of digital signal processing. Nowadays, modern methods of digital signal processing maintain a key role in research and industrial applications. Many of the best practices that have been used to control shunt active power in industrial practice for decades are now being surpassed in favor of new progressive approaches. This systematic research review classifies the importance of using advanced signal processing methods in the field of shunt active power filter control methods and summarizes the extant harmonic extraction methods, from the conventional approach to new progressive methods using genetic algorithms, artificial intelligence, and machine learning. Synchronization techniques are described and compared as well.

A comparative study of single-channel signal processing methods in fetal phonocardiography.

Fetal phonocardiography is a non-invasive, completely passive and low-cost method based on sensing acoustic signals from the maternal abdomen. However, different types of interference are sensed along with the desired fetal phonocardiography. This study focuses on the comparison of fetal phonocardiography filtering using eight algorithms: Savitzky-Golay filter, finite impulse response filter, adaptive wavelet transform, maximal overlap discrete wavelet transform, variational mode decomposition, empirical mode decomposition, ensemble empirical mode decomposition, and complete ensemble empirical mode decomposition with adaptive noise. The effectiveness of those methods was tested on four types of interference (maternal sounds, movement artifacts, Gaussian noise, and ambient noise) and eleven combinations of these disturbances. The dataset was created using two synthetic records r01 and r02, where the record r02 was loaded with higher levels of interference than the record r01. The evaluation was performed using the objective parameters such as accuracy of the detection of S1 and S2 sounds, signal-to-noise ratio improvement, and mean error of heart interval measurement. According to all parameters, the best results were achieved using the complete ensemble empirical mode decomposition with adaptive noise method with average values of accuracy = 91.53% in the detection of S1 and accuracy = 68.89% in the detection of S2. The average value of signal-to-noise ratio improvement achieved by complete ensemble empirical mode decomposition with adaptive noise method was 9.75 dB and the average value of the mean error of heart interval measurement was 3.27 ms.

Comparative analysis of wavelet transform filtering systems for noise reduction in ultrasound images.

Wavelet transform (WT) is a commonly used method for noise suppression and feature extraction from biomedical images. The selection of WT system settings significantly affects the efficiency of denoising procedure. This comparative study analyzed the efficacy of the proposed WT system on real 292 ultrasound images from several areas of interest. The study investigates the performance of the system for different scaling functions of two basic wavelet bases, Daubechies and Symlets, and their efficiency on images artificially corrupted by three kinds of noise. To evaluate our extensive analysis, we used objective metrics, namely structural similarity index (SSIM), correlation coefficient, mean squared error (MSE), peak signal-to-noise ratio (PSNR) and universal image quality index (Q-index). Moreover, this study includes clinical insights on selected filtration outcomes provided by clinical experts. The results show that the efficiency of the filtration strongly depends on the specific wavelet system setting, type of ultrasound data, and the noise present. The findings presented may provide a useful guideline for researchers, software developers, and clinical professionals to obtain high quality images.

Advanced Bioelectrical Signal Processing Methods: Past, Present and Future Approach-Part II: Brain Signals.

As it was mentioned in the previous part of this work (Part I)-the advanced signal processing methods are one of the quickest and the most dynamically developing scientific areas of biomedical engineering with their increasing usage in current clinical practice. In this paper, which is a Part II work-various innovative methods for the analysis of brain bioelectrical signals were presented and compared. It also describes both classical and advanced approaches for noise contamination removal such as among the others digital adaptive and non-adaptive filtering, signal decomposition methods based on blind source separation, and wavelet transform.

Advanced Bioelectrical Signal Processing Methods: Past, Present, and Future Approach-Part III: Other Biosignals.

Analysis of biomedical signals is a very challenging task involving implementation of various advanced signal processing methods. This area is rapidly developing. This paper is a Part III paper, where the most popular and efficient digital signal processing methods are presented. This paper covers the following bioelectrical signals and their processing methods: electromyography (EMG), electroneurography (ENG), electrogastrography (EGG), electrooculography (EOG), electroretinography (ERG), and electrohysterography (EHG).

Advanced Bioelectrical Signal Processing Methods: Past, Present and Future Approach-Part I: Cardiac Signals.

Advanced signal processing methods are one of the fastest developing scientific and technical areas of biomedical engineering with increasing usage in current clinical practice. This paper presents an extensive literature review of the methods for the digital signal processing of cardiac bioelectrical signals that are commonly applied in today's clinical practice. This work covers the definition of bioelectrical signals. It also covers to the extreme extent of classical and advanced approaches to the alleviation of noise contamination such as digital adaptive and non-adaptive filtering, signal decomposition methods based on blind source separation and wavelet transform.

A novel algorithm based on ensemble empirical mode decomposition for non-invasive fetal ECG extraction.

Non-invasive fetal electrocardiography appears to be one of the most promising fetal monitoring techniques during pregnancy and delivery nowadays. This method is based on recording electrical potentials produced by the fetal heart from the surface of the maternal abdomen. Unfortunately, in addition to the useful fetal electrocardiographic signal, there are other interference signals in the abdominal recording that need to be filtered. The biggest challenge in designing filtration methods is the suppression of the maternal electrocardiographic signal. This study focuses on the extraction of fetal electrocardiographic signal from abdominal recordings using a combination of independent component analysis, recursive least squares, and ensemble empirical mode decomposition. The method was tested on two databases, the Fetal Electrocardiograms, Direct and Abdominal with Reference Heartbeats Annotations and the PhysioNet Challenge 2013 database. The evaluation was performed by the assessment of the accuracy of fetal QRS complexes detection and the quality of fetal heart rate determination. The effectiveness of the method was measured by means of the statistical parameters as accuracy, sensitivity, positive predictive value, and F1-score. Using the proposed method, when testing on the Fetal Electrocardiograms, Direct and Abdominal with Reference Heartbeats Annotations database, accuracy higher than 80% was achieved for 11 out of 12 recordings with an average value of accuracy 92.75% [95% confidence interval: 91.19-93.88%], sensitivity 95.09% [95% confidence interval: 93.68-96.03%], positive predictive value 96.36% [95% confidence interval: 95.05-97.17%] and F1-score 95.69% [95% confidence interval: 94.83-96.35%]. When testing on the Physionet Challenge 2013 database, accuracy higher than 80% was achieved for 17 out of 25 recordings with an average value of accuracy 78.24% [95% confidence interval: 73.44-81.85%], sensitivity 81.79% [95% confidence interval: 76.59-85.43%], positive predictive value 87.16% [95% confidence interval: 81.95-90.35%] and F1-score 84.08% [95% confidence interval: 80.75-86.64%]. Moreover, the non-invasive ST segment analysis was carried out on the records from the Fetal Electrocardiograms, Direct and Abdominal with Reference Heartbeats Annotations database and achieved high accuracy in 7 from in total of 12 records (mean values µ < 0.1 and values of ±1.96σ < 0.1).

Vital Sign Monitoring in Car Seats Based on Electrocardiography, Ballistocardiography and Seismocardiography: A Review.

This paper focuses on a thorough summary of vital function measuring methods in vehicles. The focus of this paper is to summarize and compare already existing methods integrated into car seats with the implementation of inter alia capacitive electrocardiogram (cECG), mechanical motion analysis Ballistocardiography (BCG) and Seismocardiography (SCG). In addition, a comprehensive overview of other methods of vital sign monitoring, such as camera-based systems or steering wheel sensors, is also presented in this article. Furthermore, this work contains a very thorough background study on advanced signal processing methods and their potential application for the purpose of vital sign monitoring in cars, which is prone to various disturbances and artifacts occurrence that have to be eliminated.

A System for the Detection of Persons in Intelligent Buildings Using Camera Systems-A Comparative Study.

This article deals with the design and implementation of a prototype of an efficient Low-Cost, Low-Power, Low Complexity-hereinafter (L-CPC) an image recognition system for person detection. The developed and presented methods for processing, analyzing and recognition are designed exactly for inbuilt devices (e.g., motion sensor, identification of property and other specific applications), which will comply with the requirements of intelligent building technologies. The paper describes detection methods using a static background, where, during the search for people, the background image field being compared does not change, and a dynamic background, where the background image field is continually adjusted or complemented by objects merging into the background. The results are compared with the output of the Horn-Schunck algorithm applied using the principle of optical flow. The possible objects detected are subsequently stored and evaluated in the actual algorithm described. The detection results, using the change detection methods, are then evaluated using the Saaty method in order to determine the most successful configuration of the entire detection system. Each of the configurations used was also tested on a video sequence divided into a total of 12 story sections, in which the normal activities of people inside the intelligent building were simulated.

Adaptive Software Defined Equalization Techniques for Indoor Visible Light Communication.

This paper focuses on a channel feed-forward software defined equalization (FSDE) of visible light communication (VLC) multistate quadrature amplitude modulation (M-QAM) based system, implemented in the LabVIEW programming environment. A highly modular platform is introduced; the whole experiment is simulated in software and then thoroughly explored and analyzed during practical measurements in the laboratory, simulating real-world situations. The whole platform is based on modified National Instruments software defined radios (NI SDR) and a commercially available Philips light source, often used in Czech government institutions. Three FSDE algorithms were tested: least mean squares (LMS), normalized least mean squares (NLMS), and QR decomposition based RLS (QR-RLS). Based on measurements, QR-RLS provides the best results, improving measured values by up to 10%. The experiments also show that the simulated results are very similar to real measurements, thus proving the validity of the chosen approach. The whole platform manages to improve measured data simply by making changes to the software side of the testing prototype.

Design of a Measuring System for Electricity Quality Monitoring within the SMART Street Lighting Test Polygon: Pilot Study on Adaptive Current Control Strategy for Three-Phase Shunt Active Power Filters.

This study focuses on the design of a measuring system for monitoring the power quality within the SMART street lighting test polygon at university campuses with relation to testing an adaptive current control strategy for three-phase shunt active power filters. Unlike conventional street lighting, SMART elements are powered 24/7. Due to the electronic character of the power part of such mass appliances, there are increased problems with the power quality of the electric energy. Compared to the current concept of street lighting, there is a significant increase in the content of higher current harmonic components, which cause several problems in the distribution system. The test polygon contains 16 luminaires made by various manufacturers and mounted with various SMART components. Using the polygon control and monitoring system, dynamic load scenarios were selected. These scenarios tested the possibilities of different adaptive current control strategies for three-phase shunt active power filters to improve the power quality of electricity. This study focuses on three adaptive algorithms that respond to dynamic changes of current harmonics level in real-time. The possibility of active filter control was tested using FPGA, mainly due to the low latency of the filter control part.

A Review of Signal Processing Techniques for Non-Invasive Fetal Electrocardiography.

Fetal electrocardiography (fECG) is a promising alternative to cardiotocography continuous fetal monitoring. Robust extraction of the fetal signal from the abdominal mixture of maternal and fetal electrocardiograms presents the greatest challenge to effective fECG monitoring. This is mainly due to the low amplitude of the fetal versus maternal electrocardiogram and to the non-stationarity of the recorded signals. In this review, we highlight key developments in advanced signal processing algorithms for non-invasive fECG extraction and the available open access resources (databases and source code). In particular, we highlight the advantages and limitations of these algorithms as well as key parameters that must be set to ensure their optimal performance. Improving or combining the current or developing new advanced signal processing methods may enable morphological analysis of the fetal electrocardiogram, which today is only possible using the invasive scalp electrocardiography method.