1.
Org Lett
; 24(11): 2181-2185, 2022 03 25.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35266724
RESUMO
Rhodonoid natural products are found in nature as a scalemic mixture. This interesting phytochemical feature is presumed to originate from a reversible electrocyclic ring opening of the chromene core present in the biogenetic precursors of rhodonoids. Herein, we systematically investigated factors that are responsible for this racemization event. This eventually led us to complete the asymmetric total synthesis of rhodonoids A, C, D, and G.