RESUMO
In order to study voluntary movement control, we applied artificial neural networks (ANNs) to define the temporal patterns of surface electromyography (SEMG) activity used by normal subjects in performing three tasks, namely, wrist extension, continuous extension-flexion movements and extension-flexion movements for which the pause time between extension and flexion were 250 ms. SEMGs of 8 muscles were simultaneously recorded together with wrist movement. The results provided some evidence for the schema theory.
RESUMO
The illustration of the electrical properties of skin and quantitative relations provides the theory and method for transdermal drug delivery by electroporation. The paper puts forward an electrical model of skin including conductance of appendageal, lipid, lipid-corneocyte matrix pathway and Nernst potential of charged drug molecule. Leakage experiments with Tinidazole as pattern mass were carried out with three groups, each of which contained 15 protocols. The result indicates that (1) we obtained that equivalent resistance R(T) of side-by-side permeation chambers and one R(A) of transdermal decreased along with initial voltage of pulse increased using logarithm trend line fitting, but the R(T) and R(A) were gained along with pulse voltage decreased during pulse duty; (2) Even if same pulse protocol, Tinidazole permeation fluxes were difference 0-4 orders from each other for SC of different position at same time. The transdermal potential is actual exist in the molecular to pass through skin. In is more significant that conductance Ga, Gl and Gc is described permeability of molecular through skin. And it shows that electrical model of skin to expatiate quantify relationship between electrical property and molecular flow is very effective.