Analysis of the Analgesic Effect, Emotion, and Safety of Esketamine in Cesarean Section Analgesia for Puerperae.

Objective: This retrospective study aimed to evaluate the effectiveness and safety of esketamine as an analgesic during cesarean section procedures. Methods: 102 puerperae undergoing cesarean section were divided into a control group and an esketamine (SK) group. Various parameters, including HR, MAP, and postoperative pain, were analyzed. Blood gas analysis and Apgar scores were assessed in neonates. Postoperative depression and satisfaction were evaluated in puerperae. Drug concentrations were measured using liquid-phase tandem mass spectrometry. Results: No significant differences in dimension levels were observed between the two groups (P > .05). However, the SK group showed better HR and MAP indicators at various time points, less postoperative pain, and better mental well-being on postpartum days 1, 3, and 7 (P < .05). Adverse reaction rates were similar between groups (P > .05), but postoperative satisfaction was significantly different (P = .027). Neonatal outcomes did not differ significantly (P > .05). In the SK group, SK2 and SK3 groups had better results compared to SK1 (P < .05). Conclusion: Esketamine during cesarean section stabilized vital signs, reduced pain, and improved well-being in puerperae without affecting newborns. Optimal dosage: 30 µg/kg/h esketamine, 15 ng/kg/h sufentanil.

PROSPECT-PMP+: Simultaneous Retrievals of Chlorophyll a and b, Carotenoids and Anthocyanins in the Leaf Optical Properties Model.

The PROSPECT leaf optical radiative transfer models, including PROSPECT-MP, have addressed the contributions of multiple photosynthetic pigments (chlorophyll a and b, and carotenoids) to leaf optical properties, but photo-protective pigment (anthocyanins), another important indicator of vegetation physiological and ecological functions, has not been simultaneously combined within a leaf optical model. Here, we present a new calibration and validation of PROSPECT-MP+ that separates the contributions of multiple photosynthetic and photo-protective pigments to leaf spectrum in the 400-800 nm range using a new empirical dataset that contains multiple photosynthetic and photo-protective pigments (LOPEX_ZJU dataset). We first provide multiple distinct in vivo individual photosynthetic and photo-protective pigment absorption coefficients and leaf average refractive index of the leaf interior using the LOPEX_ZJU dataset. Then, we evaluate the capabilities of PROSPECT-MP+ for forward modelling of leaf directional hemispherical reflectance and transmittance spectra and for retrieval of pigment concentrations by model inversion. The main result of this study is that the absorption coefficients of chlorophyll a and b, carotenoids, and anthocyanins display the physical principles of absorption spectra. Moreover, the validation result of this study demonstrates the potential of PROSPECT-MP+ for improving capabilities in remote sensing of leaf photosynthetic pigments (chlorophyll a and b, and carotenoids) and photo-protective pigment (anthocyanins).