Body mapping of skin friction coefficient and tactile perception during the dynamic skin-textile interaction.

The clothing fabric and skin interact continuously across the many regions of users' bodies during wear, which can lead to both physical skin damage and discomfort. Therefore, this investigation aimed to explore the regional differences in skin friction, tactile perception, and sensitivity in both females and males during the skin-textile interaction. The static and dynamic friction coefficient and textile perception (texture, stickiness, pleasantness, and discomfort) were measured across the 36 selected testing body areas by using a friction measurement device. The results revealed there was a significant difference in skin friction, tactile perceptions, and sensitivity across the various body regions. The anterior neck had the highest skin friction in both females and males, and participants generally rated higher texture perception in their anterior aspects compared to posterior and lateral regions. There was no significant difference in skin friction, tactile perception ratings, and sensitivity between females and males. Practitioner summary: This study sought to examine regional variations in skin friction, tactile perception, and sensitivity during the skin-textile interaction. There was a significant difference in skin friction, tactile perceptions, and sensitivity across the various body regions and no significant sex effect on skin friction, tactile perception ratings, and sensitivity.

How do the printing parameters of fused filament fabrication and structural voids influence the degradation of biodegradable devices?

Fused Filament Fabrication (FFF), a commonly used additive manufacturing technology, is now employed widely in biomedical fields for fabricating geometrically complex biodegradable devices. Structural voids arising from the printing process exist within the objects manufactured by FFF. This paper reveals the underlying mechanism of how the printing parameters and voids affect the degradation behaviours of devices made of biodegradable polyesters. It was found that both voids and internal architecture (layer height, for instance) affect the degradation rate by interacting with the reaction-diffusion process. Large suppression of the degradation rate was found when auto-catalytic hydrolysis and diffusion are significant. Degradation rate reduced in an approximately logarithmic manner as void size increased. The extent this effect depended on the strength of auto-catalytic hydrolysis and diffusion, void size and overall device size. The internal architecture of FFF products (regulated by printing parameters) influences the degradation rate by altering the diffusion speed of acid catalysts (regulated by diffusion path length). Both void size and internal architecture should be considered in fabricating biodegradable devices using FFF. STATEMENT OF SIGNIFICANCE: A geometric model that relates printing parameters with voids of FFF is developed to characterise the structure of FFF components. Such a model, when coupled with a degradation model, offers end-to-end simulation capability (e.g. from printing parameters to degradation rate) for predicting degradation properties. The model is validated against the in vitro degradation data obtained in this study. To our knowledge, the impact of printing parameters and voids on degradation is investigated here for the first time. It is found that both the void size and the internal architecture determined by the printing parameters play an essential role in regulating degradation behaviours.

An examination of five theoretical foundations associated with localized thermosensory testing.

PURPOSE: To assess five theoretical foundations underlying thermosensory testing using local thermal stimuli. METHODS: Thermal sensation, discomfort and the confidence of thermal sensation scores were measured in 9 female and 8 male volunteers in response to 17 physical contact temperature stimuli, ranging between 18-42 °C. These were applied to their dorsal forearm and lateral torso, across two sessions. RESULTS: Thermal sensation to physical temperature relationships followed a positive linear and sigmoidal fit at both forearm (r2 = 0.91/r2 = 0.91, respectively) and lateral torso (r2 = 0.90/ r2 = 0.91, respectively). Thermal discomfort to physical temperature relationships followed second and third-order fits at both forearm (r2 = 0.33/r2 = 0.34, respectively) and lateral torso (r2 = 0.38/r2 = 0.39, respectively) test sites. There were no sex-related or regional site differences in thermal sensation and discomfort across a wide range of physical contact temperatures. The median confidence of an individual's thermal sensation rating was measured at 86%. CONCLUSION: The relation between thermal sensation and physical contact temperature was well described by both linear and sigmoidal models, i.e., the distance between the thermal sensation anchors is close to equal in terms of physical temperatures changes for the range studied. Participants rated similar thermal discomfort level in both cold and hot thermal stimuli for a given increase or decrease in physical contact temperature or thermal sensation. The confidence of thermal sensation rating did not depend on physical contact temperature.

Mechanical and hydrolytic properties of thin polylactic acid films by fused filament fabrication.

Thin polymeric films are widely used as medical applications such as cell culture, stent, drug delivery and mechanical fixation. One of the most commonly used materials is polylactic acid (PLA) - a material, which is non-toxic, biodegradable and biocompatible. Fused filament fabrication (FFF) is a preferable additive manufacturing technique to manufacture polymers, where PLA is one of the most common materials. FFF is a promising technique for customised biomedical applications due to its relatively low cost and geometrical flexibility where biomedical applications are patient tailored. This study is the first to consider FFF monolayered thin films of PLA in terms of mechanical and hydrolytic properties at 37 °C in vitro degradation. Throughout degradation, the reduction in mechanical properties was examined by analysing molecular weight and thermal properties. FFF monolayered PLA underwent autocatalytic bulk degradation with no proof of significant mass loss. Young's modulus, ultimate tensile strength and molecular weight reduced by approximately 60%, 86%, and 80% after 280 days, respectively, while the degree of crystallinity increased by 143% in comparison to benchmark thin films at day 0. It was found that the decrease in mechanical properties was more sensitive to the increase in crystallinity in the early stage of the degradation, while the molecular weight was more dominant in the late stage of the degradation. This study provides practical information in terms of mechanical properties to support medical device designers in a range of potential end-use biomedical applications to achieve safe functional products over the required degradation lifetime.

Layer-dependent properties of material extruded biodegradable Polylactic Acid.

Polylactic acid (PLA) is a biodegradable, biocompatible and non-toxic biopolymer with good mechanical properties, and is commonly used for the additive manufacture of PLA-based biomedical devices. Such devices are available in a range of sizes and thicknesses, with smaller devices capable of being realised via additive manufacturing in just a few layers. Due to their thermal history and thermal degradation, the thermal, molecular weight and mechanical properties of each layer was different when the raw material was melted, and the in-course layer was deposited to the previous layer. This study investigated the effect of the number of layers on mechanical, thermal and molecular weight properties, and the relationship between them. Material extruded ISO 527-2 type 5A specimens with 1-, 2-, 3-, 4-, 5-, 7- and 10-layers were prepared with the cutting die. Results indicated that the degree of crystallinity was found to decrease from 8% to 0.5% with an increasing number of layers. This was likely due to different cooling rates, where the molecular weight was lowest for 1-layer and increased with the increasing number of layers until it almost reached that of the bulk material. Additionally, ultimate tensile strength and strain increased with an increasing number of layers, while Young's Modulus decreased due to heterogeneous material structure. Of all obtained results, there was no significant difference between 5- and 10-layer in terms of mechanical and thermal properties.

Assessing the Design and Compressive Performance of Material Extruded Lattice Structures.

With additive manufacturing increasingly being embraced in the area of sports technology, focus has shifted toward cellular structures for impact protection. Periodic lattice structures can be tailored for a specific response by modifying the geometry of individual cells, with the structure capable of being modified to conform around a given body. However, the effect of modifying specific design characteristics within a lattice and the interrelationships between them are not well understood. This study examines five geometric design variables: cell width, strut cross-sectional area (CSA), strut shape, cell orientation, and joint filleting, and their effect on the compressive behavior of a lattice structure. Truncated octahedron lattices were manufactured using nylon through the process of material extrusion and tested under compression at a constant strain rate of 1.0 s-1. Design of experiments was utilized to analyze the results by implementing a 2(5-1) factorial design. Results indicated that the strut CSA, cell width, and interaction between the two design characteristics had the largest effects on the plateau stress of the lattice and its energy capacity.