RESUMO
Background: Scientific research is essential in medicine to practice evidence-based medicine and improve healthcare quality. Research experience enables students to hone their skills in thinking critically, understanding data, and evaluating the strengths and weaknesses of scientific articles. Objective: This study aims to determine knowledge, attitudes, and barriers toward research and assess research participation experience among medical students in Turkey. Methods: We conducted a cross-sectional study among medical students in Turkey. Data was collected using an online self-administered questionnaire. Results: A total of 487 students, 65.1% female, completed the questionnaire. The majority of students (78.9%) showed a poor level of knowledge regarding research, although 23.2% had previously participated in a research project. Females reported significantly higher positive attitude scores (32.2 versus 31.3, p = 0.034) than males. Graduates of high schools based abroad had substantially lower knowledge scores than Anatolian, Science, and Private High School graduates (1.4 versus 2.7, 2.6, 2.4; p < 0.001). Students with experience in a research project had significantly higher knowledge scores (2.7 versus 2.3, p = 0.045). Students who wish to participate in a scientific research project in their future career had both substantially higher positive attitude scores (32.4 versus 29.6, p < 0.001) and knowledge scores (2.5 versus 1.8, p < 0.001) than those with no interest. Conclusion: Most participants had a positive attitude but lacked research knowledge. Some perceived barriers were lack of funding, time, proper mentoring, laboratories, and facilities. Developing better training systems may help to convert students' positive attitudes toward research into improved knowledge, practices, and overcoming research barriers. Supplementary information: The online version contains supplementary material available at 10.1007/s40670-024-01987-0.
RESUMO
BACKGROUND: Pregnancy is a dynamic process associated with changes in vascular and rheological resistance. Maternal maladaptation to these changes is the leading cause of pregnancy complications such as preeclampsia. OBJECTIVE: This study aimed to assess the hemorheological alterations in pregnancies with a high risk for preeclampsia in the first trimester. METHODS: Ninety-two pregnant women were allocated into the high preeclampsia risk group (37 cases) and control groups (55 cases). Plasma and whole blood viscosity and red blood cell morphodynamic properties, including deformability and aggregation were assessed by Brookfield viscometer and laser-assisted optical rotational cell analyzer (LORRCA) at 11-14 gestational weeks. RESULTS: Whole blood viscosity was significantly higher in the high-risk group at all shear rates. Plasma viscosity and hematologic factors showed no differences between the groups. Hematocrit levels positively correlated with high blood viscosity only in the high-risk group. There were no significant changes in the other deformability and aggregation parameters. CONCLUSIONS: Changes in the whole blood viscosity of pregnant women with high preeclampsia risk refer to impaired microcirculation beginning from the early weeks of gestation. We suggest that the whole blood viscosity is consistent with the preeclampsia risk assessment in the first trimester, and its measurement might be promising for identifying high-preeclampsia-risk pregnancies.