The Effect of Psychological Intervention on the Visual Quality of Patients with a Diffractive Multifocal Intraocular Lens Implant.

OBJECTIVE: This study aimed to investigate the effect of psychological intervention on the visual quality of patients with a diffractive multifocal intraocular lens implant and its possible mechanism. METHODS: Eighty-nine patients undergoing age-related cataract surgery were enrolled in the study at the Affiliated Hospital of Southwest Medical University between December 2015 and July 2017. They were randomly divided into two groups: multiple focus M1 group (n = 45) and multiple focus M2 group (n = 40). The M1 group was only given routine preoperative health education, treatment, and evaluation, while the M2 group also received psychological intervention. RESULTS: After treatment, there was no statistical difference in the uncorrected distance and near visual acuity, corrected distance and near visual acuity, or the vision and near removal rate in either of the two groups (p > 0.05). However, postoperative glare was lower in the M2 group (p < 0.05), and patient satisfaction was higher in the M2 group (p < 0.05). The M2 group had a more obvious improvement in the Symptom Checklist-90 score (p < 0.05), the serum interleukin-6 (IL-6) was lower, and the serum brain-derived neurotrophic factor (BDNF) was higher in the M2 group (p < 0.05). In addition, serum IL-6 had a negative correlation with the depression score, and serum BDNF also showed a negative correlation with the anxiety score (p < 0.05). CONCLUSIONS: Psychological intervention improved the stress state of patients with age-related cataracts and diffractive multifocal intraocular lens implants, reduced the level of inflammatory factors in the body, improved the level of BDNF, reduced postoperative visual interference, and improved postoperative satisfaction.

Detection of Synthetic Cannabinoid CUMYL-PEGACLONE in E-Cigarette Oil and Hair.

OBJECTIVES: To establish a combined high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) and gas chromatography-mass spectrometry (GC-MS) method to detect the synthetic cannabinoid CUMYL-PEGACLONE in e-cigarette oil and hair. METHODS: HPLC-MS/MS and GC-MS were used to establish the detection method of CUMYL-PEGACLONE, and the hair of drug-involved persons and the seized e-cigarette oil were detected. RESULTS: The main mass spectrometry characteristic ions m/z of CUMYL-PEGACLONE measured by GC-MS were 91, 179, 197, 254 and 372. CUMYL-PEGACLONE had a good linear relationship in the mass concentration range of 2-50 ng/mL, and the linear correlation coefficient (r) was greater than 0.99. The limit of detection (LOD) of CUMYL-PEGACLONE in hair was 0.01 ng/mg, and the limit of quantitation (LOQ) was 0.02 ng/mg. The LOD of CUMYL-PEGACLONE in e-cigarette oil was 1 ng/mg, and the LOQ was 2 ng/mg. The average recoveries of CUMYL-PEGACLONE under the attempt at high, intermediate and low levels in blank human hair and e-cigarette oil matrix were 98.2%-132.4% and 93.5%-110.6%, and the intraday and intraday precision were 1.2%-12.9% and 0.7%-2.9%. CUMYL-PEGACLONE was detected in the hair of 15 drug-involved persons. Except for 1 person who was lower than LOQ, the concentration of CUMYL-PEGACLONE in the hair of other 14 persons was 0.035-0.563 ng/mg. The mass fraction of CUMYL-PEGACLONE in 2 e-cigarette oil were 0.17% and 0.21%, respectively. CONCLUSIONS: The established HPLC-MS/MS and GC-MS methods are applied to the detection of HPLC-MS/MS in drug-related cases, which provides strong evidence support for the handling authority to quickly investigate these cases, and also provides a reference for the identification of such substances in future.

The Effect and the Mechanism of Comprehensive Treatment on the Ocular Surface and the Visual Quality of Online Teachers with a Mild-to-Moderate Dry Eye Condition During the Early Phase of Coronavirus Disease 2019.

OBJECTIVE: To investigate the effect of comprehensive treatment on ocular surface function and the visual quality of online teachers with a mild-to-moderate dry eye condition during the early phase of coronavirus disease 2019 (COVID-19). METHODS: Secondary school online teachers diagnosed with a mild-to-moderate dry eye disease in our outpatient clinic from February to May 2020 were enrolled in this retrospective cross-section study, and all patients received dry eye comprehensive treatment. A questionnaire survey on eye-use habits, visual quality and dry eye-related indicators was collected before and after treatment (2 and 4 weeks). The changes and the correlations between indicators before and after treatment were compared. RESULTS: A total of 30 patients (15 females and 15 males) were included. After comprehensive treatment, patients had significantly higher central tear meniscus height (TMH), non-invasive first tear film breakup time (NIBUTf) and non-invasive average tear film breakup time (NIBUTav) than those before with statistical significance (P < 0.05). Lower ocular surface disease index (OSDI) and Meibomian gland scores were observed after treatment with statistical significance (P < 0.05). Objective scatter index (OSI), modulation transfer function (MTF) cutoff, strehl ratio (SR), and tear film objective scatter index (TF-OSI) were significantly improved after treatment (P < 0.05). Besides, TF-OSI was positively correlated with the changes in OSDI, Meibomian gland score, eye-use duration and OSI with statistical significance (P < 0.05), while it was negatively correlated with NIBUTf, NIBUTav, the TMH of the central lower eyelid, SR, sleep duration, conjunctival congestion and the MTF cutoff (P < 0.05), respectively. No correlation between TF-OSI and ciliary congestion was found (P > 0.05). CONCLUSION: Comprehensive treatment could effectively improve the symptoms and visual quality of online teachers with a mild-to-moderate dry eye condition during the early stage of COVID-19 pandemic.

An open-ended waveguide system for SAR system validation or probe calibration for frequencies above 3 GHz.

Compliance with safety guidelines prescribed in terms of maximum electromagnetic power absorption (specific absorption rate or SAR) for any 1- or 10-g of tissue is required for all newly introduced personal wireless devices such as wireless PCs. The prescribed SAR measuring system is a planar phantom with a relatively thin base of thickness 2.0 mm filled with a lossy fluid to simulate dielectric properties of the tissues. A well-characterized, broadband irradiator is required for SAR system validation or submerged E-field probe calibration for the Wi-Fi frequencies in the 5-6 GHz band. We describe an open-ended waveguide system that may be used for this purpose. Using a fourth-order polynomial least-squares fit to the experimental data gives SAR variations close to the bottom surface of the phantom that are in excellent agreement with those obtained using the finite-difference time-domain (FDTD) numerical method. The experimentally determined peak 1- and 10-g SARs are within 1 to 2% of those obtained using the FDTD both at 5.25 and 5.8 GHz.

Comparison of various safety guidelines for electronic article surveillance devices with pulsed magnetic fields.

The paper uses the two methods suggested in both the ICNIRP and proposed IEEE safety guidelines for compliance testing of security systems based on time-varying magnetic fields being introduced for electronic article surveillance (EAS), radiofrequency identification, and other applications. For nonsinusoidal pulses that are often used, the two procedures are to treat the exposure as a multifrequency exposure with various frequency components or to calculate the peak induced current densities or electric fields treating the highest of the pulses of duration t(p) as a single frequency, half sinusoid of the same duration and frequency 1/(2t(p)). Using either of the procedures, the induced current densities (J) or electric fields (E) are compared to the basic restrictions on J or E for compliance testing. Using a heterogeneous, tissue-classified anatomic model of the human body, we calculate the induced J and E for the various tissues for a realistic, EAS system for two typical nonsinusoidal pulses to show that the two methods give substantially different results. While the approximate but simpler method of treating the pulse as a half sinusoid results in peak induced J or E that may be compliant with safety guidelines, the rigorous method of treating such exposures as multifrequency exposures gives induced current densities or electric fields that may be up to twice as large, thus making such systems potentially noncompliant with the safety guidelines. Since it is more accurate, it is suggested that safety assessment based on the Fourier analysis leading to multifrequency components be used for compliance testing of such devices.

SARs for pocket-mounted mobile telephones at 835 and 1900 MHz.

Increasingly, mobile telephones are becoming pocket-sized and are being left in the shirt pocket with a connection to the ear for hands-free operation. We have considered an anatomic model of the chest and a planar phantom recommended by US FCC to compare the peak 1 and 10 g SARs for four typical cellular telephones, two each at 835 and 1900 MHz. An agreement within +/- 10% is obtained between calculated and experimental 1 and 10 g SARs for various separations (2-8 mm) from the planar phantom used to represent different thicknesses of the clothing both for the antenna away from or turned back towards the body. Because of the closer placement of the antennas relative to the body, the peak 1 and 10 g SARs are considerably higher (by a factor of 2-7) for pocket-mounted telephones as compared to the SARs obtained using a 6 mm thick plastic ear head model--a procedure presently accepted both in the US and Europe. This implies that a telephone tested for SAR compliance against the model of the head may be severely out of compliance if it were placed in the shirt pocket.

Some present problems and a proposed experimental phantom for SAR compliance testing of cellular telephones at 835 and 1900 MHz.

This paper compares the maximum allowable powers of some typical cellular telephones at 835 and 1900 MHz for compliance with the limits of specific absorption rates (SAR) given in ANSI/IEEE, ICNIRP and the proposed modification of ANSI/IEEE safety guidelines. It is shown that the present ANSI/IEEE guideline is the most conservative with the ICNIRP guidelines allowing a maximum radiated powerthat is 2.5-3 times higher, and the proposed IEEE modification of treating pinna as an extremity tissue the least conservative allowing even higher radiated powers by up to 50%. The paper also expands the previously reported study of energy deposition in models of adults versus children to two different and distinct anatomically-based models of the adult head, namely the Utah model and the 'Visible Man' model, each of which is increased or reduced by the voxel size to obtain additional head models larger or smaller in all dimensions by 11.1% or -9.1%, respectively. The peak 1 g body-tissue SAR calculated using the widely accepted FDTD method for smaller models is up to 56% higher at 1900 MHz and up to 20% higher at 835 MHz compared to the larger models, with the average models giving intermediate SARs. Also given in the paper is a comparison of the peak 1 g and 10 g SARs for two different anatomically-based models with 6 mm thick smooth plastic ear models used for SAR compliance testing. The SARs obtained with the insulating plastic ear models are up to two or more times smaller than realistic anatomic models. We propose a 2 mm thin shell phantom with lossy ear that should give SARs within +/- 15% of those of anatomic models.