1.
Chem Commun (Camb)
; 52(89): 13151-13154, 2016 Nov 18.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27763649
RESUMO
An efficient and convenient method has been developed to achieve direct silylation of unactivated remote primary or secondary C(sp3)-H bonds to form C-Si bonds with hexamethyldisilane (HMDS). This method highlights the emerging strategy to transform unactivated methyl or methylene into versatile functional groups in organic synthesis and provides a new method to construct functionalized C-Si bonds for synthetic chemistry.