RESUMO
Human papillomavirus (HPV) has been directly related to acuminate warts and cervical cancer, the second most common neoplasia among women. Given the lack of treatment against the virus itself, many medications have been utilised, mainly aiming in modifying the host's immunological response. We present the case of a 54 years old postmenopausal patient with a history of vaginal cuff wart and HPV persistence that we managed in our clinic for 6 months with a mix of curcumin, aloe vera, amla and other natural ingredients. As the patient was found to be intolerant to imiquimod (one of the most common conservative methods of treatment) we attempted the use of curcumin, which was applied to the area of the wart three times per week for 6 months. Both clinical and colposcopical improvement was noted in regular clinic visits with regression of the lesion. The outcome of this case encourages our view that curcumin should be considered as a significant treatment modality against HPV infection and acuminate warts.
Assuntos
Antineoplásicos/uso terapêutico , Condiloma Acuminado/tratamento farmacológico , Curcumina/uso terapêutico , Infecções por Papillomavirus/tratamento farmacológico , Preparações de Plantas/uso terapêutico , Doenças Vaginais/tratamento farmacológico , Adjuvantes Imunológicos/efeitos adversos , Colposcopia , Condiloma Acuminado/patologia , Combinação de Medicamentos , Álcoois Graxos/uso terapêutico , Feminino , Humanos , Imiquimode/efeitos adversos , Ácido Láctico/uso terapêutico , Pessoa de Meia-Idade , Teste de Papanicolaou , Infecções por Papillomavirus/patologia , Phyllanthus emblica , Fitoterapia , Lesões Intraepiteliais Escamosas Cervicais/tratamento farmacológico , Lesões Intraepiteliais Escamosas Cervicais/patologia , Cremes, Espumas e Géis Vaginais , Doenças Vaginais/patologia , Esfregaço Vaginal , beta-Glucanas/uso terapêuticoRESUMO
Cancer of the cervix is the fourth most common malignancy among women in the world and the sixth most common among women in Europe. Almost half of patients with an early-stage invasive cervical carcinoma are under 40â¯years of age, while the average age at first pregnancy in European countries is over 28â¯years. Therefore many women with cervical cancer have not started or completed their family at the time of diagnosis and ask for fertility-sparing surgery. Radical trachelectomy is a safe alternative to standard care (radical hysterectomy) for patients diagnosed with early-stage cervical cancer and is a reasonable choice in well selected cases. We present the case of a 23-year-old patient diagnosed with a cervical adenocarcinoma and treated with abdominal trachelectomy.