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1.
Hum Vaccin Immunother ; 19(2): 2222649, 2023 08 01.
Artigo em Inglês | MEDLINE | ID: mdl-37381762

RESUMO

During the pandemic period, many regulations were made to reduce the spread of the epidemic throughout the country and restrictions were applied. We aimed to interpret the effects of vaccination status, total number of vaccination doses and preferred vaccine type on the prognostic process of the patients we treated inpatients with the diagnosis of Covid-19 in our pandemic service. The present descriptive cross-sectional study was conducted in Ordu, Turkey. One hundred and fifty-two people participated. 80.9% (n = 123) of whom were vaccinated against SARS-Cov-2, and 19.1% (n = 29) were unvaccinated. When the treatment processes of the participants were analyzed in general, it was observed that the clinical condition of the individuals who received at least one dose of BNT162b2 vaccine did not worsen (χ2 = 40.080; p = .011). It was determined that BNT162b2 vaccine was not among the vaccine preferences of the cases who needed to be transferred to the intensive care unit in this process and whose clinical processes resulted in death during follow-up in intensive care or service after intensive care referral (χ2 = 64.417; p = .024). According to these results, our study proves once again the protective role of vaccines against epidemic diseases and their progression.


Assuntos
COVID-19 , Vacinas , Humanos , Vacina BNT162 , COVID-19/prevenção & controle , Vacinas contra COVID-19 , Estudos Transversais , Estudos Prospectivos , SARS-CoV-2 , Vacinação , Pandemias
2.
Pak J Med Sci ; 37(4): 972-978, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34290768

RESUMO

OBJECTIVES: Examine the effect of fasting during Ramadan on kidney functions in patients with chronic kidney disease. METHODS: The study was conducted on 130 patients with stage III-IV chronic kidney disease (CKD), who were admitted to the Ordu University nephrology polyclinic during the month before Ramadan and one month after Ramadan in 2019. Blood samples were taken in the morning after 12 hours of fasting. RESULTS: There was a statistically significant difference between BUN in the fasting group before and after the month of Ramadan. The median BUN before Ramadan was 26.65 mg/dl, the median after Ramadan was 24.05 mg/dl (p=0.004).There was a statistically significant difference between the nonfasting groups before and after Ramadan with respect to creatinine level. Median creatinine before Ramadan was 1.69 mg/dl,and the median after Ramadan was 1.86 mg/dl (p <0.001).There was a statistically significant difference between the fasting groups before and after Ramadan with respect to creatinine levels. Fasting group ,the median before Ramadan was 1.5 mg/dl, and the median after Ramadan was 1.42 mg/dl (p = 0.038).The impact of independent variable of fasting, using linear regression was found to be statistically significant (ppost-<0.001). The eGFR was 14.826 points higher in those who fasted after Ramadan than in those who did not. CONCLUSION: Fasting during the month of Ramadan does not deteriorate kidney functions and even leads to a moderate improvement in kidney functions. Taking these results into consideration, fasting may be advised for patients with stage III-IV CKD who want to fast and remain in stable condition.

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