[The value of Wagner and Selvester's electrocardiographic point indices for assessing global and regional function of the left ventricle in patients with ischemic heart disease]. / Stoinost na elektrokardiografskite tochkovi indeksi na Wagner i Selvester za otsenka na globalnata i regionalnata funktsiia na liavata kamera pri bolni s iskhemichna bolest na surtseto.

The study includes 45 patients with ischemic heart disease. The reproducibility of Selvester's QRS-point index was examined by two researchers (r = 0.98). Between the ejection fraction of the left ventricle and the ECG-pont indices there exists a reverse relation, the correlation coefficients being equal (r = -5.58). Between the segmental disturbances of the left ventricular wall movements, examined by the systolic shortening in percentage of the radial axes, and both ECG indices there is also an equal correlation (r = 0.59). The relation between the angiographically evaluated segmental disturbances and the ejection fraction is also reverse, r = -0.88. The results of the study prove the relatively great possibility for mistakes of only the routine rest ECG is analyzed. The ECG evaluation of the left ventricular function cannot disclose the compensatory reserves of the healthy myocardium.

[Preoperative clinical and hemodynamic characteristics of patients with mitral valve defects subjected to valve prosthesis]. / Predoperativna klinichna i khemodinamichna kharakteristika na bolni s mitralen klapen porok, podlozheni na klapno protezirane.

Sixty one patients were studied that were subjected to mitral valvular prosthesis--28 patients with pure or prevailing mitral stenosis, 12 with pure or prevailing mitral insufficiency and 21 patients with degree competitive stenosis and insufficiency. The patients, to have mitral valvular prosthesis, undergo the operation, most often, in the presence of pronounced pulmonary capillary and arterial hypertension and preserved right-ventricular and left-ventricular function. The pulmonary hypertension is with the highest values in the patients with mitral stenosis leading. In the patients with leading stenosis, passes of compromised right-ventricular function could be established. The cases with disturbed left-ventricular function are from the groups with prevailing mitral insufficiency or competitive stenosis and insufficiency. The time for mitral valvular prosthesis should be selected so as not to allow the manifestation of bilateral cardiac insufficiency as well as the formation of essential pulmonary disorders.

[Hemodynamic indices assessed by impedance cardiography in patients with the subacute stage of myocardial infarct before and during bicycle ergometry]. / Khemodinamichni pokazateli, pretseneni s impedansna kardiografiia, pri bolni sus subakuten stadii na miokarden infarkt predi i pri veloergometriia.

The hemodynamic indices were determined in 51 patients with myocardial infarction, subacute stage, before and after bicycle ergometric loading. The following indices were determined by impedance cardiography: cardiac output, total peripheral resistance, volume velocity of blood ejection, power of cardiac contractions, index of myocardial contractility etc. The results reveal that the patients with subacute stage of myocardial infarction have reduced reserve possibility of blood circulation apparatus. Signs of latent cardiac failure are manifested in case of extensive localization with transmural involvement, because of seven disorders in the contractile function of myocardium. The adaptation to physical loading, in the rest of the patients, is better but still far less than that in healthy subjects.

[Computer calculation of echocardiographic indices]. / Kompiuturno izchislenie na ekhokardiografskite pokazateli.

The objective of the study was to determine the degree of discrepancy in the data from echocardiographic indices, determined by the original Bulgarian apparatus "Echocomputer" (engineer Daskalov) and by two independently working researchers as well as the accuracy of repetition by one researcher. M-echocardiographic records were used for that purpose of 22 patients with various cardiopathies, the indices determined by the computer were compared with the data of the same indices but obtained by calculations according to the well known classical formulae. Two statistical methods were used--variation and correlation analysis. No statistically significant difference was established between the compared values of Echocomputer and considerable correlation dependence in the comparison of the data from two different ways of calculation of EchoCG-indices.

[Relaxation and filling of the left ventricle measured by computer analysis of the unidimensional (M-type) echocardiogram in healthy subjects and patients with hypertrophic cardiomyopathy]. / Relaksatsiia i pulnene na liavata kamera, opredeleni s kompiuturen analiz na ednorazmernata (N-tip) ekhokardiograma pri zdravi i bolni s khipertrofichna kardiomiopatiia.

The indices of systolic and earli diastolic function (relaxation and rapid filling) were established in 16 healthy subjects and 35 patients with idiopathic hypertrophic cardiomyopathy by computer analysis ("Echocomputer" RIEMT--MA, Sofia) and left ventricular and mitral valve M-type echocardiogram. In a considerable part of the partients with hypertrophic cardiomyopathy, pathological changes were established in the diastolic function of left ventricle--lengthening of iso-voluminal relaxition, reduction of velocity and increase of the dimension of left ventricular cavity, reduction of velocity and fraction of blood flow in the phase of rapid filling of left ventricle. Those changes of diastolic function are a manifestation of increased resistance, restriction of left ventricular filling that could partially explain the tendency to reduction of stroke and minute volume in some patients with hypertrophic cardiomyopathy with normal and increased indices of systolic function of left ventricle (fraction of shortening, ejection fraction, veloycity of reduction of dimension of left ventricle in the phase of ejection)? There is considerable correlation between the changes of diastolic function and those of the hypetrophic process and reduction of left ventricular cavity. The computer analysis of the echogram, enables the more detailed, fast and accurate determination of important indices of diastolic and systolic function of left ventricle, with a good repeated reproducibility.

[Diastolic and systolic functions of the left ventricle determined by M-echocardiography in idiopathic hypertrophic cardiomyopathy]. / Diastolna i sistolna funktsiia na liavata kamera, opredelena s M-ekhokardiografiia pri idiopatichna khipertrofichna kardiomiopatiia.

The diastolic function and the correlation between pump and diastolic function of left ventricle were studied in 35 patients with idiopathic hypertrophic cardiomyopathy with subaortic stenosis via a M-echocardiographic investigation by Echoview 80 C in the routine method. The following indices were used: A. For the diastolic function: 1. Telediastolic dimension (TDD) and volume (TDV) of left ventricular cavity. 2. Dimension (DPhFF) and volume (VPhFF) of the left ventricular cavity at the end of the phase of fast filling; 3. Velocity of fast filling of the left ventricle (ml/sec) - (formula; see text) 4. Fraction of fast filling of left ventricle (%) - (formula; see text) 5. Velocity of backward motion of the anterior mitral cusp at the beginning of diastole (E - F segment); 6. Velocity of early diastolic motion of the posterior wall of left ventricle (PWLV); 7. Ratio between early diastolic (D) and systolic (S) interval of PWLV: D/S; 8. Telediastolic interval (A - C) of mitral valve; 9. Index of fast emptying of left ventricle; 10. Amplitude E - E' of mitral echogram; II. Area (cm2) between two mitral cusps in diastole. B. For the systolic (pump) function: 1. Stroke and minute volume (SV, MV) of left ventricle according to the cubic formula and Teicholz formula; 2. Telesystolic dimension (TSD) and volume (TSV) of left ventricular cavity; 3. Fraction of shortening (FS) of left ventricle (%); 4. Mean velocity of shortening of the circumferential fibres (mVcf) of left ventricle (circumf./S); 5. Ejection fraction (EF) of left ventricle (%). 6. Distance between left ventricular endocardium of interventricular septum and point E of mitral valve; 7. Fraction of systolic thickening of IVS and PWLV; 8. Velocity of systolic thickening of IVS and PWLV; 9. Amplitude of systolic motion of IVS and PWLV.(ABSTRACT TRUNCATED AT 250 WORDS)