RESUMO
Childhood obesity is an urgent problem of pediatric endocrinology due to the widespread occurrence, the development of metabolic complications and their steady tracking into adulthood. The developed clinical guidelines are the main working tool of the practitioner. They briefly and structurally present the main information about the epidemiology and modern classification of obesity, methods of its diagnosis and treatment based on the principles of evidence-based medicine.
Assuntos
Endocrinologia , Obesidade Infantil , Adulto , Criança , Medicina Baseada em Evidências , Humanos , Obesidade Infantil/diagnóstico , Obesidade Infantil/epidemiologia , Obesidade Infantil/terapiaAssuntos
Monitoramento Ambiental/métodos , Iodo/deficiência , Programas de Rastreamento/métodos , Doenças da Glândula Tireoide , Área Programática de Saúde , Criança , Monitoramento Epidemiológico , Bócio Endêmico/epidemiologia , Bócio Endêmico/metabolismo , Bócio Endêmico/prevenção & controle , Humanos , Hipotireoidismo/epidemiologia , Hipotireoidismo/metabolismo , Hipotireoidismo/prevenção & controle , Incidência , Iodo/uso terapêutico , Prevalência , Federação Russa/epidemiologia , Cloreto de Sódio na Dieta/uso terapêutico , Doenças da Glândula Tireoide/epidemiologia , Doenças da Glândula Tireoide/metabolismo , Doenças da Glândula Tireoide/prevenção & controleRESUMO
AIM: To assess efficacy of different methods of iodine prophylaxis in pregnant women living in conditions of goiter endemia. MATERIAL AND METHODS: Standard clinical, laboratory and device tests for iodine deficiency according to WHO criteria were made in 156 pregnant women living in the territory affected by goiter endemia. Of them, 121 examinees had no thyroid pathology, 35 ones had diffuse euthyroid goiter. All of them received different kinds of iodine prophylaxis. RESULTS: The occurrence of neonatal TTH values over 5 iU/l in neonates born by mothers free of thyroid pathology on potassium iodide prophylaxis when pregnant was 9.1%. This is much lower than in conventional iodine prophylaxis--17.24% (p < 0.01). A comparative analysis of the efficacy of potassium iodide-200 in pregnant women with diffuse euthyroid goiter and its combination with L-thyroxine has shown that by the effect on lessening frequency of neonatal TTH over 5 iU/l the above schemes do not differ significantly, thyroid reduction is more prominent in pregnant women on thyroxine with potassium iodide. CONCLUSION: The index of neonatal TTH is an objective criterium to control efficacy of different methods of iodine prophylaxis in pregnancy.