1.
Biochem Mol Biol Educ
; 40(6): 400-1, 2012.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23166030
RESUMO
3D visualization assists in identifying diverse mechanisms of protein-DNA recognition that can be observed for transcription factors and other DNA binding proteins. We used Proteopedia to illustrate transcription factor-DNA readout modes with a focus on DNA shape, which can be a function of either nucleotide sequence (Hox proteins) or base pairing geometry (p53). © 2012 by The International Union of Biochemistry and Molecular Biology.