1.
Endoscopy
; 56(S 01): E299-E300, 2024 Dec.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38569500
2.
Intern Med
; 61(8): 1145-1150, 2022 Apr 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34565776
RESUMO
Fontan-associated liver disease (FALD) caused by long-term systemic venous congestion following the Fontan procedure may eventually lead to hepatocellular carcinoma (HCC). Treatment strategies for HCC due to FALD (FALD-HCC) remain unclear. We herein report a 35-year-old man with FALD-HCC that was well controlled by 3 cycles of continuous infusion of 5-fluorouracil and low-dose cisplatin (low-dose FP therapy) combined with 60 Gy of radiation therapy. However, the patient ultimately died of extrahepatic metastases. A pathological autopsy revealed more than 90% necrosis in the primary HCC lesion. This case suggests that low-dose FP therapy might be effective in FALD-HCC.
Assuntos
Carcinoma Hepatocelular , Técnica de Fontan , Neoplasias Hepáticas , Adulto , Protocolos de Quimioterapia Combinada Antineoplásica/uso terapêutico , Carcinoma Hepatocelular/etiologia , Carcinoma Hepatocelular/terapia , Cisplatino/uso terapêutico , Fluoruracila/uso terapêutico , Técnica de Fontan/efeitos adversos , Humanos , Infusões Intra-Arteriais/efeitos adversos , Neoplasias Hepáticas/patologia , Masculino , Complicações Pós-Operatórias/etiologia
3.
Pediatr Int
; 45(6): 743-6, 2003 Dec.
Artigo
em Inglês
| MEDLINE
| ID: mdl-14651555