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J Pediatr Hematol Oncol ; 46(7): 380-382, 2024 Oct 01.
Artigo em Inglês | MEDLINE | ID: mdl-39262396

RESUMO

Lymphomas originating from the meninges without brain or systemic involvement represent an extremely rare type of primary central nervous system lymphomas. Here, we report a case of primary dural lymphoma in a 3-year-old boy who was brought to the hospital due to headache, nausea, and vomiting episodes ongoing for several days. An acute hematoma in the right frontoparietal region was detected on a brain CT scan. The patient underwent surgery to remove the hematoma, which was then sent for pathologic examination. The pathology report revealed lymphoblastic B-cell lymphoma with a Ki-67 proliferation index of 80%. Radiologic and FDG-PET/CT imaging, as well as bone marrow examination, did not reveal any systemic disease. The NHL BFM 2012 lymphoblastic lymphoma treatment protocol was started and successfully completed. The patient has been followed for ~2 years and is still alive and disease-free. This is the first case of pediatric primary dural lymphoblastic B-cell lymphoma ever reported in the literature.


Assuntos
Hematoma , Humanos , Masculino , Pré-Escolar , Hematoma/etiologia , Hematoma/patologia , Neoplasias Meníngeas/patologia , Neoplasias Meníngeas/complicações , Protocolos de Quimioterapia Combinada Antineoplásica/uso terapêutico , Leucemia-Linfoma Linfoblástico de Células Precursoras/complicações , Leucemia-Linfoma Linfoblástico de Células Precursoras/patologia , Leucemia-Linfoma Linfoblástico de Células Precursoras/diagnóstico , Dura-Máter/patologia , Dura-Máter/diagnóstico por imagem
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