A cost effective method for the preparation of sodium fluoride [18F]NaF for PET-CT imaging by using an in-house designed module.

We report the development of a manual module for the preparation of [18F]NaF for metastatic bone cancer imaging. By using this simple module, [18F]NaF production can be carried out inexpensively without using commercially available kits. The module can be used for making [18F]NaF from freshly irradiated H218O water or with left over activity in the target after [18F]FDG production. The product meets all quality control parameters.