A Treatise on Electrode Carrier Dislocation in Visual Prosthetic Devices.

Visual implants electrically activate adjacent neurons to induce artificial perception for visual impairment patients to restore some sight. Proximity of electrode carrier to the ganglion cell has attracted careful consideration due to its implications on secure electrochemical and single-localized stimulation. In this study, we postulate a novel strategy to treat the proximity of electrode-cell. A simulation framework includes the carrier dislocation using the geometric parameters of Argus II® epiretinal electrode carrier design. Lastly, we present results on the offset angle of displacement.Clinical Relevance- This postulates a novel strategy to treat the dislocation of electrode carrier confined with a single tack.

Synthesis of an organic conductive porous material using starch aerogels as template for chronic invasive electrodes.

We report the development of an organic conducting mesoporous material, as coat for invasive electrodes, by a novel methodology based on the use of starch aerogel as template. The poly(3,4-ethylenedioxythiophene) (PEDOT) aerogel was synthesized by polymerization of 3,4-ethylenedioxythiophene within a saturated starch aerogel with iron (III) p-toluenesulfonate (oxidizing agent) and subsequent removal of the polysaccharide template, followed by supercritical CO2 drying. The chemical structure and oxidation state of the resulting material were studied by Raman spectroscopy. The morphology and surface properties of the obtained nanoporous material were investigated by scanning electron microscopy (SEM), micro computed tomography (µCT) and nitrogen adsorption-desorption techniques. The composition and thermal behaviour were evaluated by energy dispersive spectroscopy (EDS) and thermogravimetric analysis (TGA) respectively. A preliminary biocompatibility test verified the non-cytotoxic effects of the PEDOT aerogel. The large surface area and wide pore size distribution of the PEDOT conductive aerogel, along with its electrical properties, enable it to be used as extracellular matrix scaffold for biomedical applications.