Using Interteaching to Promote Online Learning Outcomes.

Due to the COVID-19 pandemic, educators have been forced to rapidly transition away from in-person learning environments to completely online formats. Many of these educators have had little or no training and experience teaching online, contributing to stress and anxiety. To compound this problem even further, there are a multitude of online learning technologies from which to choose that can be relatively costly and require an intensive production process. In an effort to provide immediate relief to those dealing with this problem, we detail how interteaching, an empirically supported behavioral teaching technique, can be used to cultivate an interactive online learning environment in either an asynchronous or synchronous format. Specifically, we describe some best practices and provide some examples on how to generate active student responding (ASR) as well as provide pinpointed performance-based feedback. We specifically reference the relatively easy-to-use online software Kaltura, but it is hoped that our suggestions inspire others to develop and use these strategies across a variety of platforms in effort to provide evidence-based quality education during this crisis.

The Value and Validity of Self-Reported Survey Data on the Rape Experiences of College Students.

Self-reported survey data on the extent and nature of rape and sexual assault experienced by a population represent an important source of information because these crimes often go unreported, and are thus undercounted in law enforcement or other official statistics. This article compares Campus Climate Survey Validation Study (CCSVS) data to Clery Act data in an effort to (1) assess the validity of the CCSVS data and the Clery Act data based on the extent to which they corroborate one another, and (2) estimate the extent to which Clery Act data potentially underestimate the true incidence of rape. The results help to establish the extent to which self-report surveys on sexual victimization are needed to understand the magnitude of the problem among a given population.

Sensitivity of Sexual Victimization Estimates to Definitional and Measurement Decisions.

Self-report surveys are subject to measurement error associated with variation in the methodology employed. The current analysis uses data from the Campus Climate Survey Validation Study (CCSVS) to examine the impact that measurement decisions have on estimates. The findings demonstrate that asking victims to provide detailed information in an effort to properly place incidents in time and classify incidents by type resulted in relatively minor decreases in estimate magnitude. Ultimately, asking respondents to provide or confirm additional incident-level information for proper classification resulted in more complete information with very little impact on estimates.

Reducing excessive questions in adults at adult-day training centers using differential-reinforcement-of-low rates.

Differential-reinforcement-of-low rate (DRL) schedules are often used to reduce, not eliminate, behavior. We systematically replicated Austin and Bevan (2011) to determine whether the number of questions asked by two adults with intellectual disabilities working at adult-day-training centers could be reduced using a full-session DRL. The full-session DRL involved delivery of a reinforcer at the end of the day if the number of questions asked was less than a specified number during the entire session. Questions, up to a specified number, were also reinforced within-session. The full-session DRL reduced the number of questions asked by both participants and increased duration of task engagement for one participant.

Methods for Improving Representativeness in a Web Survey on Sexual Assault Among College Students.

Many colleges and universities conduct web-based campus climate surveys to understand the prevalence and nature of sexual assault among their students. When designing and fielding a web survey to measure a sensitive topic like sexual assault, methodological decisions, including the length of the field period and the use or amount of an incentive, can affect the representativeness of the respondent sample leading to biased or imprecise estimates. This study uses data from the Campus Climate Survey Validation Study (CCSVS) to assess how the interaction between field period length and survey incentive amount affects nonresponse, sample representativeness, and the precision of survey estimates. Research suggests that using robust incentives gives potential survey respondents a reason to complete the survey beyond their intrinsic motivation to do so. Likewise, extending the field period gives more time to people who may be less intrinsically motivated to complete the survey. Both serve to increase sample size and representativeness, minimize bias, and improve estimate precision. Schools, however, sometimes lack the time and/or resources for both a robust incentive and a lengthy field period, and this study examines the extent to which the potential negative impacts of not using one can be mitigated by the presence of the other. Findings indicate that target response rates can be achieved using a smaller incentive if the field period is lengthy but, even with a lengthy field period, the use of a smaller incentive can result in biased estimates due to a lack of representativeness. Conversely, when a robust incentive is used and weights are developed to adjust for nonresponse, a shorter field period will not have a significant impact on point estimates, but the estimates will be less precise due to fewer respondents participating in the survey.

Gambling-related cognitive distortions predict level of function among US veterans seeking treatment for gambling disorders.

BACKGROUND AND OBJECTIVES: Gambling Disorder (GD) is characterized by recurrent gambling behavior that is associated with significant impairment and distress, high psychiatric comorbidities, and high functional disability. The military veteran population appears particularly susceptible to developing the disorder, but relatively little has been studied among this population. The purpose of the present study is to investigate the clinical psychopathologies and comorbidities of veterans seeking treatment for problem gambling and how problem gambling may impact functioning. METHODS: Treatment-seeking veterans meeting criteria for GD (N = 61) underwent a structured clinical interview and completed the South Oaks Gambling Screen (SOGS), the Gambling Symptom Assessment Scale (G-SAS), the Yale-Brown Obsessive-Compulsive Scale for Gambling Disorder (PG-YBOCS), the Gambling Belief Questionnaire (GBQ), the Barratt Impulsiveness Scale (BIS-11), and the Sheehan Disability Scale (SDS). RESULTS: Veterans seeking treatment for GD had high rates of psychiatric and addiction disorder comorbidities. Few veterans had previously sought treatment and most reported substantive challenges in social and occupational functioning. When determining how gambling-related characteristics (ie, severity and cognitive distortions) impact function, severity of cognitive distortions was the strongest statistical predictor of overall functional disability. CONCLUSIONS AND SCIENTIFIC SIGNIFICANCE: The findings from this study indicate that there is high comorbidity between GD and other psychiatric and addictive disorders, as well as social and occupational functioning. In addition, cognitive distortions related to gambling relate importantly to overall functioning and should be considered in the development of interventions for veterans with GD. (Am J Addict 2018;27:108-115).

Reinforcer magnitude affects delay discounting and influences effects of d-amphetamine in rats.

Impulsive choice in humans can be altered by changing reinforcer magnitude; however, this effect has not been found in rats. Current levels of impulsive choice can also influence effects of d-amphetamine. This study used a within-subject assessment to determine if impulsive choice is sensitive to changes in reinforcer magnitude, and whether effects of d-amphetamine are related to current levels of impulsive choice. A discounting procedure in which choice was for a smaller reinforcer available immediately or a larger reinforcer available after a delay that increased within session was used. Reinforcer magnitude was manipulated between conditions and impulsive choice was quantified using area under the curve (AUC). In the Smaller-Magnitude (SM) Condition, choice was between one food pellet and three food pellets. In the Larger-Magnitude (LM) Condition, choice was between two food pellets and six food pellets. Impulsive choice was greater in the SM Condition compared to the LM Condition. Further, effects of d-amphetamine (0.1-1.8mg/kg) were related to differences in impulsive choice. d-Amphetamine increased impulsive choice in the LM Condition, but had no effect on impulsive choice in the SM Condition. Overall, these results show that impulsive choice in rats is sensitive to changes in reinforcer magnitude, and that effects of d-amphetamine are influenced by current levels of impulsive choice.

Disclosure of sexual assault experiences among undergraduate women at historically black colleges and universities (HBCUs).

OBJECTIVE: To document the sexual assault disclosure experiences of historically black college or university (HBCU) students. PARTICIPANTS: A total of 3,951 female, undergraduate students at 4 HBCUs. METHODS: All women at the participating schools were recruited in November 2008 to participate in a Web-based survey including both closed- and open-ended questions. Survey data were weighted for nonresponse bias. RESULTS: The majority of sexual assault survivors disclosed their experience to someone close to them, but disclosure to formal supports, particularly law enforcement agencies, was extremely rare. Nonreporters had concerns about the seriousness of the incident and their privacy. On the basis of qualitative data, strategies identified by students to increase reporting included more education and awareness about sexual assault, more survivor services and alternative mechanisms for reporting, and better strategies for protecting the confidentiality of survivors. CONCLUSIONS: Official sexual assault victimization data are of limited utility in conveying the extent of sexual assault among HBCU students, and efforts to increase reporting, such as peer education and enhanced confidentiality procedures, are needed.

Extra (non-contingent) food does not affect behavioral tolerance to d-amphetamine's rate-decreasing effects.

Tolerance refers to the diminished effect of a drug following its repeated administration such that a larger dose is needed to obtain the initial effect. Tolerance to a drug's effects on operant behavior is more likely to develop when initial drug administration results in a loss of reinforcement. It remains unknown how offsetting loss of reinforcement influences the development of tolerance. Providing extra (non-contingent) food pellets was hypothesized to impede the development of tolerance to effects of a repeatedly administered dose of d-amphetamine that reduced the number of food pellets earned by rats. A multiple schedule with two variable-interval (VI) 60-s components resulting in food delivery was used to maintain lever pressing. Extra food pellets were provided in one of those components according to a variable-time (VT) 120-s or a VT 30-s schedule for separate groups of rats (n=6 for each group). Effects of d-amphetamine (0.1-3.0mg/kg) were tested before (acute) and during (chronic) injections (45days) of an individually selected, repeatedly administered dose that reduced the number of food pellets earned by at least 50% compared to when saline was tested acutely. There was a dose-dependent decrease in lever-press rates and food pellets earned. The development of tolerance was quantified by dividing the area-under-the-curve (AUC) of the chronic dose-effect function by the AUC of the acute dose-effect function. Tolerance developed to a similar extent in components with and without extra food pellets for rats in both groups. These results indicate that offsetting reinforcement loss, at least as studied here, did not differentially affect tolerance development.

Measuring Sexual Victimization: On What Fronts is the Jury Still Out and Do We Need it to Come In?

Rennison and Addington use National Crime Victimization Survey (NCVS) data to document the fact that college women experience violent victimization at a lower rate than women of the same age who do not attend college, which refutes the idea that women in college are at increased risk of being victimized. The measurement of victimization, especially sexual victimization, is, however, a topic that has be the source of much debate. Bureau of Justice Statistics is currently exploring what are the best methods for measuring sexual victimization within the NCVS, and recent methodological research, which is summarized in this article, could inform this process. Although consensus has seemingly been forming around come methods, such as using self-administered survey instruments and behaviorally specific questions when trying to measure sexual victimization, the jury is still out on some other design fronts. What is not clear is whether we need the jury to come in, so to speak. Some methodological variation might be acceptable, especially if the various methods being considered are producing similar results.

The KRAB zinc finger protein RSL1 modulates sex-biased gene expression in liver and adipose tissue to maintain metabolic homeostasis.

Krüppel-associated box zinc finger proteins (KRAB-ZFPs) are a huge family of vertebrate-specific repressors that modify gene expression in an epigenetic manner. Despite a well-defined repression mechanism, few biological roles or gene targets of KRAB-ZFP are known. Regulator of sex-limitation 1 (RSL1) is a mouse KRAB-ZFP that enforces male-predominant expression in the liver, affecting body mass and pubertal timing. Here we show that female but not male Rsl1(-/-) mice gain more weight than wild-type mice on a high-fat diet (HFD) and that key liver and white adipose tissue (WAT) metabolic genes are altered in both Rsl1(-/-) sexes in response to dietary stress. Expression profiling of Rsl1-sensitive genes in liver and WAT indicates that RSL1 accentuates sex-biased gene expression in liver but greatly diminishes it in WAT. RSL1 expression solely in liver is sufficient to limit diet-induced weight gain and suppress lipogenic genes in WAT, indicating that RSL1 balances metabolism via liver-to-adipose-tissue communication. RSL1's effects on adult physiology exemplify a significant modulatory capacity of KRAB-ZFPs, in the absence of which there is widespread metabolic dysregulation. This ability to buffer against gene expression noise, coupled with extensive individual genetic variation, highlights the enormous potential of KRAB-Zfp genes as candidate risk factors for complex diseases.

Intimate partner violence victimization among undergraduate women at Historically Black Colleges and Universities (HBCUs).

Despite the evidence that young and minority women may be particularly vulnerable to intimate partner violence (IPV), there is little research on the IPV experiences of minority undergraduate women. This study addresses this gap by estimating the prevalence of IPV and examining factors associated with experiencing IPV among undergraduate women attending Historically Black Colleges or Universities (HBCUs). Findings suggest alarmingly high victimization rates; however, factors associated with IPV among HBCU women are similar to those found in prior research with women in the general population. The results also suggest that some risk factors are differentially associated with experiencing specific types of IPV.

The context and consequences of sexual assault among undergraduate women at Historically Black Colleges and Universities (HBCUs).

To examine the context of sexual assault and postassault actions and consequences among women attending historically Black colleges or universities (HBCUs), web-based surveys were administered in November 2008 to 3,951 undergraduate women attending four HBCUs. Data on the context in which assaults occurred were generated for women who had been sexually assaulted since entering college (n = 358). Multivariate models were run on the full sample to examine the association between sexual assault and symptoms of depression and posttraumatic stress disorder (PTSD). Results indicated that most survivors were assaulted by assailants well known to them and when the survivor and perpetrator were drinking alcohol. Very few survivors disclosed their experiences to formal sources of support. Survivors had significantly more symptoms of depression and were more likely to screen positive for PTSD than nonvictims. Further research on disclosure and its moderating role on the mental health consequences of sexual assault is needed.

The KRAB zinc finger protein RSL1 regulates sex- and tissue-specific promoter methylation and dynamic hormone-responsive chromatin configuration.

Over 400 Krüppel-associated box zinc finger proteins (KRAB-ZFPs) are encoded in mammalian genomes. While KRAB-ZFPs strongly repress transcription in vitro, little is known about their biological function or gene targets in vivo. Regulator of sex limitation 1 (Rsl1), one of the first KRAB-Zfp genes assigned a physiological role, accentuates sex-biased liver gene expression, most dramatically for mouse sex-limited protein (Slp), which provides an in vivo reporter of KRAB-ZFP function. Slp is induced in males in the liver and kidney by growth hormone (GH) and androgen, respectively. In the liver but not kidney, the Rsl1 genotype correlates with methylation of a CpG dinucleotide in the Slp promoter that is demethylated at puberty. RSL1 binds 2 kb upstream of the Slp promoter, both in vitro and in vivo, within an enhancer containing response elements for STAT5b. Chromatin immunoprecipitation (ChIP) assays demonstrate that RSL1 recruits KAP1/TRIM28, the corepressor for KRAB action in vitro, to this enhancer. Slp induction requires rapid cycling of STAT5b in chromatin. Remarkably, RSL1 simultaneously binds adjacent to STAT5b with a reciprocal binding pattern that limits hormonal response. These experiments demonstrate a surprisingly dynamic interplay between a hormonal activator, STAT5b, and a KRAB-ZFP repressor and provide unique insights into KRAB-ZFP epigenetic mechanisms.

A within-subject analysis of d-amphetamine exposure on delay discounting in rats.

Studies concerning the relation between stimulant drug exposure and subsequent delay discounting (impulsive choice) have resulted in mixed findings that could be related to the type of stimulant drug exposure or the use of between-subject comparisons. The purpose of the present study was to examine effects of prior D-amphetamine exposure on subsequent delay discounting using a within-subject assessment. Two groups of rats were trained under a discrete-trials choice procedure until delay discounting was stable. One group of rats then received repeated administration of 3.0 mg/kg D-amphetamine in their home cage for 14 consecutive days, while the other group received saline. After a three-week drug-free period, delay discounting was reassessed. No significant differences in area under the curve within (before or after drug exposure) or between (saline or D-amphetamine) groups were found. Thus, delay discounting was not systematically affected following termination of repeated 3.0 mg/kg D-amphetamine exposure in the present experimental arrangement. The current results, coupled with past research, indicate that there may be a distinction between cocaine exposure and D-amphetamine exposure on subsequent delay discounting; however, within-subject comparisons of cocaine exposure on delay discounting are warranted.

Preference reversals and effects of D-amphetamine on delay discounting in rats.

Impulsive choice is correlated with behavioral problems such as attention-deficit/hyperactivity disorder and substance abuse. Effects of stimulant drug administration on impulsive choice are not consistent and may depend on baseline differences in impulsive choice. A within-session delay-discounting procedure in which choice was between one food pellet delivered immediately (impulsive choice) and three food pellets delivered after increasing delays (self-controlled choice) was used to determine effects of adding and subtracting delays common to both reinforcers on impulsive choice in male Sprague-Dawley rats (n=8). Delay discounting was observed and impulsive choice was quantified using area under the curve (AUC). Adding delays common to both reinforcers decreased impulsive choice and subtracting delays common to both reinforcers increased impulsive choice. Before administration of D-amphetamine (0.03-1.80 mg/kg, intraperitoneally), subjects were rank ordered into a low-AUC or a high-AUC group. Select doses of D-amphetamine decreased impulsive choice for subjects in the low-AUC group but not for subjects in the high-AUC group. These results indicate that impulsive choice can be altered by changing the delay common to both reinforcers and suggest that effects of D-amphetamine may depend, in part, on baseline differences in impulsive choice.

Strain differences in delay discounting between Lewis and Fischer 344 rats at baseline and following acute and chronic administration of d-amphetamine.

Stimulant drugs have been shown either to increase or decrease rates of delay discounting (impulsive choice). These mixed findings may result from genetic, neurochemical, or environmental factors. Lewis (LEW) and Fischer 344 (F344) rats have neurochemical and behavioral differences that may be relevant to delay discounting and were used to examine effects of acute and chronic administration of d-amphetamine (d-AMP) on impulsive choice using a within-session delay-discounting procedure. Male LEW (n=8) and F344 (n=8) rats chose between one food pellet delivered immediately and three food pellets delivered after an increasing delay. Saline and d-AMP (0.1, 0.3, 1.0, and 1.7 mg/kg) were tested acutely and during chronic d-AMP exposure. Choice for the larger reinforcer decreased as the delay to its presentation increased for both strains at baseline. LEW rats made more impulsive choices than F344 rats as indicated by shorter indifference points, and this is consistent with previous research. Acute administration of d-AMP dose dependently increased larger-reinforcer choice and area under the curve (AUC) for LEW, but not F344 rats. During chronic exposure to d-AMP, larger-reinforcer choice and AUC increased relative to acute administration for F344 rats responding in shorter delay series, but not for F344 rats responding in longer delay series or for LEW rats. Differential effects of acute and chronic administration of d-AMP on impulsive choice in LEW and F344 rats may be a result of various factors, including genetic, neurochemical, and environmental variables. Future research should attempt to tease apart the relative contribution of each of these factors on impulsive choice.

The sexual assault of undergraduate women at historically Black colleges and universities (HBCUs).

Although research has shown that undergraduate women are at high risk for experiencing sexual assault, little research has been conducted with undergraduate women who are attending a historically Black college or university (HBCU). The purpose of this research is to document the prevalence of different types of sexual assault among undergraduate women at HBCUs and make comparisons to data collected from undergraduate women at non-HBCUs. Data on sexual assault victimization were collected from 3,951 undergraduate women at HBCUs using a cross-sectional, web-based survey. These data are compared to data collected from 5,446 undergraduate women at non-HBCUs using the same research methods. Findings indicate that approximately 9.7% of undergraduate women at HBCUs report experiencing a completed sexual assault since entering college. This rate is considerably lower than the comparable rate obtained from undergraduate women at non-HBCUs (13.7%). This difference seems to be associated with differences in alcohol-use frequency. Perhaps undergraduate women at HBCUs drink alcohol much less frequently and are thus less likely to be sexually assaulted when they are incapacitated and unable to provide consent. Alcohol use frequency, while controlling for other factors, seems to have an independent association with the likelihood of an undergraduate woman being sexually assaulted. Implications for the creation and delivery of sexual assault risk reduction and prevention policies and programs are discussed.

Women's sexual orientations and their experiences of sexual assault before and during university.

PURPOSE: We sought to examine relationships between women's sexual orientations and their sexual assault experiences before and during university. METHODS: Self-reported responses on a web-based survey of 5,439 female undergraduates who participated in the Campus Sexual Assault study were analyzed to compare three groups: bisexuals, lesbians, and heterosexuals. Groups were compared in terms of the prevalence of sexual assault before and during university, and the extent to which sexual assault before university predicted sexual assault during university. FINDINGS: The prevalence of sexual assault before and during university was higher among bisexuals and lesbians compared with heterosexuals (25.4% of bisexuals, 22.4% of lesbians, and 10.7% of heterosexuals were sexually assaulted before university; 24.0% of bisexuals, 17.9% of lesbians, and 13.3% of heterosexuals were sexually assaulted during university). Sexual assault before university was highly predictive of sexual assault during university, especially among non-heterosexuals. Compared with heterosexuals not sexually assaulted before university (the referent group), previously assaulted non-heterosexuals (bisexuals/lesbians) had eight times the odds of sexual assault during university (adjusted odds ratio [AOR] = 8.75), whereas previously assaulted heterosexuals had four times the odds of sexual assault during university (AOR, 4.40). However, there was no difference in the odds of sexual assault during university between non-heterosexuals not sexually assaulted before university and heterosexuals not sexually assaulted before university. CONCLUSION: Bisexual and lesbian women are more likely than heterosexual women to be sexually assaulted before and during university. Sexual assault before university is linked to sexual assault during university for all women, with this association being especially pronounced among non-heterosexuals.

The mediating effect of depressive symptoms on the relationship between traumatic childhood experiences and drug use initiation.

Stressful experiences such as childhood trauma and depressive symptoms have both been implicated in the initiation of drug use; however, longitudinal designs have not yet been used to elucidate their respective roles to better understand the causal sequence. In the present study, a sensitivity analysis was conducted using two mediation strategies to examine how this sequence may differ by various levels of statistical control, including (1) the standard mediational model in which the effect of lifetime traumatic stressors (Year 1) on the onset of drug use (Years 3 and 4) is mediated by levels of depressive symptoms (Year 2); and (2) a stronger test of causality such that the effect of lifetime traumatic stressors (Year 1) on the onset of drug use (Years 3 and 4) was mediated by changes in depressive symptoms (Year 1 to 2), measured by a residualized change score that controlled for levels in Year 1. Two types of trauma were studied in a community-based study of 489 Hispanic preadolescents (aged 10-12): (a) the number of lifetime traumatic stressors and (b) seven specific lifetime stressors. We also controlled for new onset traumatic stressors occurring between Years 1 and 2. Primary findings indicate that drug use initiation during early adolescence (e.g., ages 14-16) may not be tied to immediate proximal perturbations in risk factors, such as traumatic experiences and depressive symptoms. Rather, the effects of trauma on depression in this sample appear to be established earlier in childhood (ages 10-14 or younger) and persist in a relatively stable manner into middle adolescence when the risk for drug use may be heightened.