1.
Pediatr Int
; 45(3): 355-8, 2003 Jun.
Artigo
em Inglês
| MEDLINE
| ID: mdl-12828598
Assuntos
Medula Óssea/virologia , Varicela/patologia , Eritroblastos/patologia , Anticorpos Antivirais/sangue , Medula Óssea/patologia , Varicela/sangue , Varicela/complicações , Humanos , Lactente , Masculino , Recidiva , Aplasia Pura de Série Vermelha/complicações , Aplasia Pura de Série Vermelha/virologia
2.
Br J Haematol
; 118(4): 1163-5, 2002 Sep.
Artigo
em Inglês
| MEDLINE
| ID: mdl-12199801
RESUMO
We report X-linked thrombocytopenia (XLT) in a 6-year-old girl with petechiae and thrombocytopenia from the age of 3 months. Her 2-year-old brother was also diagnosed with XLT. The Wiskott-Aldrich syndrome protein (WASP) gene was detected as a replacement of +5th G to Aon intron 6 using sequence analysis, and the WASP expression levels in this patient were one-third those of a healthy control. The X-inactivation analysis of the patients lymphocytes showed a random pattern of X-chromosome inactivation. To our knowledge, this is the first confirmed report of XLT in a female.