Contributing factors of delay in seeking treatment for childhood diarrheal diseases in Berbere Woreda, Ethiopia: an unmatched case-control study.

BACKGROUND: A major cause of diarrheal illness mortality is a failure to seek immediate medical assistance. There is currently no evidence on the reasons that induce caregivers in Berbere Woreda to delayed seeking timely treatment for under-five children with diarrheal illnesses. As a result, the goal of this study was to identify determinants of delay in seeking timely treatment for childhood diarrheal diseases in Berbere Woreda, Bale Zone Oromia Region, South Eastern Ethiopia. METHODS: An unmatched case-control study on 418 child caregivers was conducted from April to May 2021. Cases were 209 children and their caregivers who sought treatment after 24 h of the onset of diarrheal disease symptoms, and controls were 209 children and their mothers/caregivers who sought treatment within 24 h of the onset of diarrheal disease symptoms. Data were collected through interviews and chart reviews using consecutive sampling. A multivariable logistic regression analysis was carried out, with variables with a P-value of 0.05 considered statistically significant. The Hosmer-Lemshow goodness of fit test was used to validate the model, and the variance inflation factor (VIF) was used to test for multi-collinearity. RESULTS: In this study, we found that among 418 participants, determinants of delay in seeking timely treatment for childhood diarrheal diseases included mothers with more than two under-five children (AOR = 2.23, 95% CI 1.21-4.11), Divorce (AOR = 2.62, 95% CI 1.087-2.76), age of children < 24 months (AOR = 1.597, 95%,CI (1.008-2.531), and preference for a government health facility for treatment (AOR = 2.56, 95% CI 1.51-4.34). Besides, the odds of mothers aged 25-34 years being two times more likely to delay seeking timely treatment for 5 children with diarrhea were 1.537 (0.560-4.213). CONCLUSIONS: Age of children, age of mothers, number of children, preference of health facilities, and marital status were factors influencing the failure to seek treatment within 24 h of recognizing diarrhea in children under the age of five.

Perceived risk of COVID-19 pandemic on crop production: an implication for food security in Ethiopia.

BACKGROUND: Risk perception is a subjective psychological construct that is influenced by cognitive, emotional, social, cultural, and individual differences, both within and between individuals and across countries. Although the impact of COVID-19 on short- and long-term food security is difficult to predict, some risk factors and lessons from previous pandemics can be identified. The goal of this study is to assess rural farmers' perceptions of the COVID-19 pandemic's impact on crop production and its implications for food security in West Arsi Zone, Oromia, Ethiopia. METHODS: A community-based cross-sectional study was conducted among 634 small-holder farmers in the west Arsi zone district. From November 1-30, 2020, data was gathered through interviews with local farmers. Data was gathered using a semi-structured questionnaire. Six trained expert agricultural workers were used as data collectors and supervisors, respectively, and both were trained. The questionnaire had been pre-tested. The Statistical Package for the Social Sciences (SPSS) software version 25 was used to analyze the data. To identify factors associated with risk perception of the COVID-19 pandemic on crop production, binary and multivariable logistic regression were used, with statistical significance determined at a p-value of 0.05. RESULTS: This study found that among farmers in West Arsi Zone, Oromia, Ethiopia, about 32.5% reported having perceived risk of COVID-19 pandemic on crop production, and that age greater than or equal to 57, female sex (AOR,1.48 95% CI (1.03-2.12)), primary Educational status (AOR,2.85(1.78-4.58)), and permanent employed occupation of the house head (AOR, 2.27(1.24-4.17) were found to be independent predictors of perceived risk of COVID-19 pandemic on crop production among farmers in West Arsi Zone, Oromia, Ethiopia. CONCLUSION: Perceived risk of COVID-19 on crop production was high and varied across age groups, sexes, educational attainment levels, and the occupation of the head of the household.

Prevalence of high-risk human papillomavirus infections and associated factors among women living with HIV in Shashemene town public health facilities, Southern Ethiopia.

BACKGROUND: Every year, large number of women are suffering from cervical cancer. Particularly women living with HIV are at high-risk of being suffered with it. Early testing of high-risk human papillomavirus infection can significantly reduce the incidence of cervical cancer. However, lack of early and regular testing has been identified as one of the major problems among risky populations. METHODS: Institutional-based cross-sectional study design was conducted among women living with HIV in Shashemene town public health facilities with a total sample size of 406 from February 1-March 30, 2022. Systematic random sampling technique was employed to select the study subjects. A structured questionnaire and checklist was used to collect data. The collected data were cleaned, coded, and entered into Epi-info version 7.2.5 and exported to statistical package for social science version 24 for analysis. Finally, bi-variable and multivariable logistic regression analyses were performed to identify determinants of high-risk human papillomavirus. Odds ratio with 95% confidence interval was used to test association between exposure and outcome under study and p-value < 0.05 was considered significant. RESULTS: The prevalence of high-risk HPV infections among study participant was 173(35.2%) with 95% CI (30.5%-40.1%). Prevalence of high-risk HPV type 16, 18 and other high-risk HPV types were 62(15.3%), 23(5.7%) and 58(14.3%), respectively. Having history of sexually transmitted infections [AOR = 3.120; 95% CI (1.977-4.923)], Endline CD4 count < 200 cells/mm3 [AOR = 3.072; 95% CI(1.009-9.350)], Endline HIV viral-load ≥ 50 copies/ml [AOR = 3.446; 95% CI(1.368-8.683)] and more than one-lifetime sexual partner [AOR = 2.112; 95% CI(1.297-3.441)] were significantly associated with high-risk HPV infections. CONCLUSION: More than one third of women living with HIV had high-risk HPV. Having history of STI, low CD4 count, high viral load and multiple sexual partners were associated with high risk HPV. HIV positive women with these risk factors should be given special consideration in clinical and public health intervention.

Predictors of time to recovery from uncomplicated severe acute malnutrition among 6-59 months children treated in out patient treatment in health posts of Nagele Arsi district: a retrospective cohort study.

BACKGROUND: Access to outpatient therapeutic feeding programs (OTP) for all children who have uncomplicated severe acute malnutrition (SAM) remains a global public health priority. Identifying predictors that determine time-to-recovery from severe acute malnutrition optimize therapeutic success. However, reliable evidence on the determinants of time to recovery at health posts was not available in Nagele Arsi district of South Ethiopia. OBJECTIVE: This study was aimed to identify determinants of time-to-recovery from uncomplicated SAM among children aged (6-59) months treated at an OTP in health posts of Nagele Arsi district, Southern Ethiopia. METHODS: Institutional based retrospective cohort study was conducted among 357 children treated in Negele Arsi district from July1, 2018 to June 30, 2020. The children were selected using simple random sampling from 20 health posts. SAM treatment outcomes were compared against international SPHERE standards. The average time-to-recovery was estimated using Kaplan-Meier survival curve and the independent predictors of time to recovery were determined using multivariable Cox-proportional hazard model. The strength of the association was done using adjusted hazard ratio (AHR) with 95% confidence intervals. Statistical significance was declared at p value < 0.05. The results were presented by text, tables and figures. RESULT: A total of 284 (79.6%) children recovered during follow up. The mean weight gain for recovered children was 4.7 + 2.4 g/kg/day. The median time-to-recovery was 44 days 95% CI (42.7-45.3). Children who received Amoxicillin, AHR =2.574, 95% CI (1.879-3.525); de-wormed, AHR = 1.519, 95% CI (1.137-2.031); received Vitamin A, AHR = 2.518, 95% CI, (1.921-3.301) and new admissions, AHR = 1.823, 95%CI, (1.224-2.715) were more likely to recover. However, those who admitted with non-edema, AHR = 0.256, 95% CI, (0.189-0.346); had cough at admission, AHR = 0.513, 95 CI, (0.366-0.719) and had diarrhea at admission AHR = 0.5, 95% CI, 0.5 (0.350-0.712) were less likely to recover. CONCLUSION AND RECOMMENDATION: The recovery rate was within the acceptable ranges of International Sphere Standards. Those children who had cough and diarrhea should be given due attention from health extension workers and program planners. Appropriate provision of routine medication and timely intervention of co-morbidity are needed to increase chance of early recovery.

Predictors of Late Presentation for HIV/AIDS in West Arsi Zone Public Health Institutions, South Ethiopia: Unmatched Case-Control Study.

BACKGROUND: Late presentation for HIV/AIDS care is defined as individuals newly presenting for HIV/AIDS care with a CD4 count below 350 cells/µl or presenting for care with WHO clinical staging of stage III or IV. Globally, around 21.7 million people living with HIV/AIDS were receiving ART in 2017, with an increase of 2.3 million since 2016. Despite this progress, most people start ART late in their disease progression. OBJECTIVE: This study aims to identify predictors of late presentation for HIV/AIDS among people living with HIV and attending ART clinics in West Arsi Zone public health institutions, South Ethiopia, 2019. METHODOLOGY: A facility-based unmatched case-control study was conducted among people living with HIV attending ART clinics in West Arsi Zone public health institutions, with a total sample size of 500 (167 cases and 333 controls). The sample size was calculated using Epi info version 7 and participants were selected using the case-based control selection sampling technique. Descriptive statistics were carried out to summarize the data. Bi-variate binary logistic regression analysis was carried for selecting candidate variables for multivariate binary logistic regression. A p-value of <0.05 was taken to declare the presence of a statistical association between outcomes and explanatory variables. RESULTS: Rural residence (AOR=7.74 95% CI (3.4-17.6)), being single (AOR=0.18 95% CI (0.06-0.49)) symptom(s) at first HIV diagnosis (AOR=7.69 95% CI (4.09-14.4)), no private house (AOR=5.09 95% CI (2.47-10.45)), fear of losing job (AOR=4.12 95% CI (2.04-8.31)), alcohol consumption (AOR=4.35 95% CI (2.18-8.69), and having chronic medical illness (AOR=5.04 95% CI (2.48-10.24)) were identified as having significant associations with late presentation of HIV/AIDS care. CONCLUSION: Rural residence, fear of losing a job, and chronic medical illness were potential risk factors for late presentation of HIV/AIDS care. Being single is the only protective factor for the late presentation of HIV/AIDS care.