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World J Microbiol Biotechnol ; 37(6): 103, 2021 May 20.
Artigo em Inglês | MEDLINE | ID: mdl-34013421

RESUMO

Microbiocides are used to control problematic microorganisms. High doses of microbiocides cause environmental and operational problems. Therefore, using microbiocide enhancers to make microbiocides more efficacious is highly desirable. 2,2-dibromo-3-nitrilopropionamide (DBNPA) is a popular biodegradable microbiocide. D-Amino acids have been used in lab tests to enhance microbiocides to treat microbial biofilms. In this investigation, D-tyrosine was used to enhance DBNPA against Desulfovibrio vulgaris biofilm on C1018 carbon steel. After 7 days of incubation, the mass loss of coupons without treatment chemicals in the ATCC 1249 culture medium was found to be 3.1 ± 0.1 mg/cm2. With 150 ppm (w/w) DBNPA in the culture medium, the mass loss was reduced to 1.9 ± 0.1 mg/cm2 accompanied by a 1-log reduction in the sessile cell count. The 150 ppm DBNPA + 1 ppm D-tyrosine combination attained an extra 3-log reduction in sessile cell count and an additional 30% reduction in mass loss compared with 150 ppm DBNPA only treatment. The combination also led to a smaller maximum pit depth. Linear polarization resistance (LPR), electrochemical impedance spectrometry (EIS), and potentiodynamic polarization (PDP) tests corroborated the enhancement effects.


Assuntos
Biofilmes/efeitos dos fármacos , Carbono/química , Desulfovibrio vulgaris/fisiologia , Nitrilas/farmacologia , Tirosina/química , Corrosão , Meios de Cultura/química , Desulfovibrio vulgaris/efeitos dos fármacos , Espectroscopia Dielétrica , Testes de Sensibilidade Microbiana , Nitrilas/química , Oxirredução , Aço/química , Sulfatos/metabolismo
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