1.
J Am Chem Soc
; 125(44): 13308-9, 2003 Nov 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-14582997
RESUMO
Using transferred cross-correlated relaxation and DFT calculations, the conformation of the relevant conformation of N5,N10-methylenetetrahydromethanopterin, a reaction intermediate bound to the 80 kD H2-forming N5,N10-methylenetetrahydromethanopterin dehydrogenase is determined. The conformation of the intermediate differs from the free form in solution and makes the reaction mechanism plausible.