Perceptions of COVID-19 vaccination and factors influencing COVID-19 vaccine acceptance among indigenous peoples in Quebec, Canada: Insights from a facebook posts and comments analysis.

Vaccination rates in Canada tend to be lower among Indigenous peoples than the rest of the population. The COVID-19 pandemic provided an unprecedented opportunity to better understand Indigenous perceptions about vaccination. The aim of this study was to explore perceptions of COVID-19 vaccine and other factors influencing COVID-19 vaccine acceptance as evidenced by public posts and comments on Facebook by Indigenous peoples in Quebec, Canada. We collected data on 95 Facebook pages or groups used by Indigenous peoples in Quebec between November 1, 2020, to June 15, 2021. To identify posts relating to COVID-19 vaccination, a keyword search ("vaccination," "vaccine," "shot," "does," "Moderna," "Pfizer") was carried out in English and French in the search bar of each Facebook page/group. Results show that First Nations peoples and Inuit in Quebec had important concerns about the usefulness, safety and effectiveness of COVID-19 vaccine. They also expressed fear of being used as test subjects for the rest of the population. Motivations mentioned by First Nations peoples and Inuit to get vaccinated against COVID-19 included to travel again and return to normal life with their loved ones, and the desire to protect the most vulnerable in their communities, especially Elders. Results show that Indigenous health care professionals were considered as reliable and trustful source of information regarding COVID-19, and that seeing role models being vaccinated build confidence and foster acceptance of the vaccine. Culturally adapted messages and vaccination campaigns by and for Indigenous peoples appear to be key to building trust toward COVID-19 vaccination.

Feasibility and clinical value of virtual reality for deep infiltrating pelvic endometriosis: A case report.

Deep infiltrating pelvic endometriosis and its surgical management is associated with a risk of major postoperative complications. Magnetic Resonance Imaging (MRI) is recommended preoperatively in order to obtain the most precise mapping of the extent of endometriotic lesions. The aim of this work was to assess the feasibility and clinical interest of 3D modeling by surface rendering as a preoperative planning tool in a patient with deep infiltrating pelvic endometriosis. We report on a 42 years old patient with history of endometriosis and persistent pain underwent pre operative imaging with MRI that was consistent with deep infiltrating endometriosis. A 3D model of the deep infiltrating endometriosis was generated from the MRI and retrospectively compared to the intra-operative findings. The nodule's location and relationship to the uterus and the rectum was clearly defined by the 3D model and correlated with surgical findings. Virtual reality based on 3D models could be an interesting tool to assist in the preoperative planning of complex surgeries.

Impact of surgery for colorectal endometriosis on postoperative fertility and pregnancy outcomes.

INTRODUCTION: Deep infiltrative endometriosis can lead to infertility with a spontaneous pregnancy rate between 8.7 and 13%. Surgical treatment of bowel endometriosis may improve spontaneous and ART fertility. The aim of this study was to evaluate post-operative fertility according to the surgical technic used (shaving vs. bowel resection). MATERIAL AND METHOD: A retrospective, monocentric study was carried-out in the University Hospital of Strasbourg, France, from September 2009 to October 2016. All patients with a desire to become pregnant and treated for colorectal deep infiltrating endometriosis were included. Two groups were analyzed and compared: shaving treatment vs. digestive resection (discoid or segmental). The primary outcome was pregnancy rate after surgery. Secondary outcomes were: mode of pregnancy occurrence (spontaneous versus ART), time of onset, term at birth, occurrence of complications during pregnancy. RESULTS: 94 patients were included (39 had a bowel resection and 55 a shaving). Both groups had similar pre-operative characteristics. The pregnancy rate was 52,1% for the total population with no significant differences between the two groups (p = 0.68). However, we found a significantly higher spontaneous pregnancies rate among the resection group with 73.7% (p = 0,0086). Pregnancy complications occurred in 50% of pregnancies, regardless of the surgical technic used. CONCLUSION: This study suggests that, for patients with colorectal DIE, surgical treatment improves overall fertility. Furthermore, resection surgery seems to significantly improve the occurrence of spontaneous pregnancies. However, this surgery is not without risks and multidisciplinary discussions and thorough information to the patient are a prerequisite.