1.
Bioorg Med Chem Lett
; 12(4): 641-3, 2002 Feb 25.
Artigo
em Inglês
| MEDLINE
| ID: mdl-11844690
RESUMO
A versatile route for the synthesis of homochiral alpha-ketoamide analogues of amino acids is described. Incorporation of this functionality into peptide sequences using either solution or solid-phase chemistry resulted in potent inhibitors of the Hepatitis C Virus NS3 proteinase.