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Introduction: Vaginal hematoma is commonly treated by traditional incision and sutures. In this report, we describe the treatment of a spontaneous vaginal hematoma after vaginal delivery by ultrasound-guided urokinase injection. Case Presentation: A 32-year-old multipara developed a spontaneous vaginal hematoma after vaginal delivery. The hematoma diagnosed via ultrasound examination of the postpartum pelvic basin was located in the posterior vaginal wall, and measured to be 8.92 × 5.71 cm from transvaginal ultrasonography. After considering the size and position of the hematoma, treatment by urokinase injection under ultrasound guidance was selected and performed three times. Forty-two days after the last treatment, the hematoma had disappeared. Discussion and Conclusion: For patients in stable condition, when incision and sutures of vaginal hematoma after natural delivery is difficult to perform, urokinase injection under ultrasound guidance can be an effective treatment method that helps in the absorption of the hematoma.
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OBJECTIVE: To investigate the anti-aging effect of polysaccharides from Urtica lobatifolia (Urtica polysaccharides) on subacute aging mice induced by D-galactose. METHODS: 90 mice were randomly divided into six groups: normal group, aging mice model group, V(E) group [100 mg/(kg x d), ig], high level of Urtica polysaccharides group [200 mg/(kg x d), ig], medium level of Urtica polysaccharides group [100 mg/(kg x d), ig] and low level of Urtica polysaccharides group [50 mg/(kg x d), ig]. The normal group was injected saline [10 mL/(kg x d), sc], while the other groups were injected D-galactose [150 mg/(kg x d), sc]. After six weeks, all the animals were weighed. After eight arm maze experiment and swimming endurance experiment, serum, liver and brain was collected. The content of protein in serum,liver and brain was detected. Total antioxidant capacity (T-AOC), activities of total superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px), and malondialdehyde (MDA) content in liver and brain samples were evaluated by kits. RESULTS: Compared with the model group, Urtica polysaccharides groups mice had larger body weight, longer swimming time, shorter time out of the maze and fewer numbers of error, as well as higher protein content in serum, liver and brain. The capacity of T-AOC, the activities of SOD and GSH-Px of polysaccharides groups in brain and liver tissue were increased significantly, and the MDA content was decreased significantly. CONCLUSION: Polysaccharides from Urtica lobatifolia has anti-aging effects on aging model mice, and the mechanism may be related to its antioxidant effect.