RESUMO
Chip-scale photonic systems that manipulate free-space emission have recently attracted attention for applications such as free-space optical communications and solid-state LiDAR. Silicon photonics, as a leading platform for chip-scale integration, needs to offer more versatile control of free-space emission. Here we integrate metasurfaces on silicon photonic waveguides to generate free-space emission with controlled phase and amplitude profiles. We demonstrate experimentally structured beams, including a focused Gaussian beam and a Hermite-Gaussian TEM10 beam, as well as holographic image projections. Our approach is monolithic and CMOS-compatible. The simultaneous phase and amplitude control enable more faithful generation of structured beams and speckle-reduced projection of holographic images.
RESUMO
The aim of the study was to test the hypothesis that the mechanism of glycogen metabolism has taken place in gills rather than in liver during Cd exposure. Male tilapia were exposed to 44.45 µM ambient Cd for 12h, and we found blood glucose significantly increased, however, lactate levels showed no significant changes. The glycogen phosphorylase (GP) activity increased immediately after 0.75 to 3h of Cd exposure in the gills, and after 1 to 6h in the liver, respectively. In addition, the glycogen level depleted faster in the gills than in the liver. Plasma cortisol level increased from 0.25 to 1h and recovered after 3h, while the glucagon did not significantly change during Cd exposure. Glucocorticoid receptor (GR) mRNA expression decreased after 0.75 h in the gills, while it significantly increased after 6h in the liver. Ca(2+), Na(+), Cl(-), and K(+) significantly decreased upon Cd exposure within 6h following Cd-induced toxic stress. We suggested that the cortisol is the spontaneous stimulation of glycogen metabolism in the gills, and it triggers a subsequent energy supply later in the liver. Taken together, the profile of glycogen metabolism between gills and liver during Cd-exposure stress provide good support to our hypothesis.
Assuntos
Cádmio/toxicidade , Brânquias/metabolismo , Glicogênio/metabolismo , Fígado/metabolismo , Tilápia/metabolismo , Animais , Glicogênio Hepático/metabolismo , MasculinoRESUMO
Juvenile tilapia were acutely exposed to 0.2 and 2 mg/L Cu(2+) for up to 144 h. The Na(+)-K(+)-ATPase (NKA)-specific activity in the gills of tilapia exposed to 0.2 mg/L Cu(2+) significantly decreased over 48-72 h and was restored to the control level after 96 h, but was again depressed during 120-144 h. The whole-body Cl(-) levels significantly decreased after 48 h, but recovered shortly afterwards and continued to do so until 144 h with 0.2 mg/L Cu exposure. During 48-72 h, the numbers of the wavy-convex type of mitochondria-rich (MR) cells appeared to significantly increase and the cortisol content also significantly increased. Changes in MR cell morphology might be necessary in order to enhance Cl(-) uptake, and this might be related to changes in cortisol levels. Whole-body Na(+) concentrations had significantly decreased by 72 h, but recovered during 96-144 h. Whole-body Cu(2+) concentrations also significantly increased compared to the initial concentration during 72-144 h of Cu exposure. All measured parameters (NKA activity, Na(+) concentration, and MR cell numbers) significantly decreased in fish exposed to 2 mg/L Cu, and no recovery was observed. These data demonstrate that juvenile tilapia strived to maintain physiological functions after exposure to sub-lethal concentrations of Cu.
Assuntos
Cobre/toxicidade , Tilápia/fisiologia , Poluentes Químicos da Água/toxicidade , Animais , Região Branquial/ultraestrutura , Cloretos/metabolismo , Cobre/farmacocinética , Brânquias/metabolismo , Brânquias/ultraestrutura , Hidrocortisona/metabolismo , Microscopia Eletrônica de Varredura , Sódio/metabolismo , ATPase Trocadora de Sódio-Potássio/metabolismo , Poluentes Químicos da Água/farmacocinéticaRESUMO
The first example of supramolecular metallomesogens derived from palladium complexes exhibiting columnar phase is reported, and the formation of the mesophase is induced by H-bonding in a tetrameric assembly.