[Analysis of Pregnancy Outcomes After Fetal Reduction in Monochorionic, Dichorionic, and Trichorionic Triplet Pregnancies].

Objective: To compare the pregnancy outcomes of pregnancy outcomes after selective fetal reduction treatment in monochorionic, dichorionic, and trichorionic triplet pregnancies. Methods: We conducted a retrospective analysis of the clinical data of 118 pregnant women carrying triplets. All subjects underwent regular prenatal check-ups and were admitted for delivery at West China Second University Hospital, Sichuan University between January 1, 2012 and January 31, 2021. According to the chorionicity, the subjects were divided into a monochorionic group ( n=13), a dichorionic group ( n=44), and a trichorionic group ( n=61). Within each group, the subjects were further divided into two subgroups, a reduction group and an expectant treatment group, according to whether they underwent fetal reduction or not. The clinical data and pregnancy outcomes were compared between the subgroups within each group. Results: In the monichorionic group, the reduction subgroup had a lower preterm birth rate and higher neonatal birth body mass than those of the expectant management subgroup, but the differences were not statistically significant. In the dichorionic and trichorionic groups, the rates of preterm delivery, neonatal hospitalization, and serious complications of the reduction subgroups were lower than those of the expectant subgroups ( P<0.05), while the neonatal birth body mass was higher in the reduction subgroups than that in the expectant subgroups ( P<0.05). In the dichorionic group, the incidence of intrahepatic cholestasis during pregnancy was lower in the reduction subgroup than that in the expectant treatment subgroup. In all 3 groups, there was no statistically significant difference between the subgroups in the incidence of gestational diabetes, hypertensive disorders of pregnancy, premature rupture of membranes, and postpartum hemorrhage. The survival curve analysis showed that women receiving fetal reduction during the first trimester had a lower risk of pregnancy loss and more significant prolonged of gestational age than those undergoing the procedure during the second trimester. Conclusion: Fetal reduction of triplets can significantly prolong the gestational age and improve the perinatal prognosis. In addition, selective reduction in the first trimester may lead to greater benefits than selective reduction in the second trimester does.

Characteristic quantum phase in Heisenberg antiferromagnetic chain with exchange and single-ion anisotropies.

We investigate the ground-state phase diagram for a spin-one quantum Heisenberg antiferromagnetic chain with exchange and single-ion anisotropies in an external magnetic field by using the infinite time-evolving block decimation algorithm to compute the ground-state fidelity per lattice site. We detect all phase boundaries solely by computing the ground-state fidelity per lattice site, with the prescription that a phase transition point is attributed to a pinch point on the ground-state fidelity surface. Furthermore, the results indicate that a magnetization plateau corresponds to a fidelity plateau on the ground-state fidelity surface, thus offering an alternative route for investigating the magnetization processes of quantum many-body spin systems. We characterize all phases by using the local-order parameter, the spin correlation, the momentum distribution of the spin correlation structure factor, and mutual information as a function of the lattice distance. The commensurate and incommensurate phases are distinguished by the mutual information. In addition, the central charges at criticalities are identified by performing a finite-entanglement scaling analysis. The results show that all phase transitions between spin liquids and magnetization plateaus belong to the Pokrovsky-Talapov universality class.

Enhanced oxidation stability of quasi core-shell alloyed CdSeS quantum dots prepared through aqueous microwave synthesis technique.

Quasi core shell alloyed CdSeS quantum dots (QDs) have been prepared through a facile aqueous-phase route employing microwave irradiation technique. The optical spectroscopy and structure characterization evidenced the quasi core shell alloyed structures of CdSeS QDs. The X-ray diffraction patterns of the obtained CdSeS QDs displayed peak positions very close to those of bulk cubic CdS crystal structures and the result of X-ray photoelectron spectroscopy data re-confirmed the thick CdS shell on the CdSe core. The TEM images and HRTEM images of the CdSeS QDs ascertained the well-defined spherical particles and a relatively narrow size distribution. On the basis, the stability of the obtained QDs in an oxidative environment was also discussed using etching reaction by H2O2. The experiments result showed the as-prepared QDs present high tolerance towards H2O2, obviously superior to the commonly used CdTe QDs and core-shell CdTe/CdS QDs, which was attributed to the unique quasi core-shell CdSeS crystal structure and the small lattice mismatch between CdSe and CdS semiconductor materials. This assay provided insight to obtain high stable crystal structured semiconductor nanocrystals in the design and synthesis process.

[Study on absorption mechanism of puerarin and its nanoparticles across Caco-2 cell model].

OBJECTIVE: To study the absorption mechanism of puerarin and its nanoparticles across Caco-2 cell model. METHODS: The Caco-2 monolayer model was used to explore the effect of time and drug concentration on the absorption of puerarin and its nanoparticeles. The drug concentration was determined by high-performance liquid chromatography and the Papp was caculated. RESULTS: The puerarin-PLGA-NP could significantly improve the absorption of puerarin. Puerarin was not only absorbed simply through passive diffusion, but also had relations with high dispersion of nanoparticles, increase of affinity and interaction with intestinal mucous membrane. CONCLUSION: The main mechanism of puerarin and its nanoparticles across Caco-2 monolayer model is passive transference. Puerarin-NP could increase the absorption of the drug in intestinal epithlial.

[Studies on chemical constituents of Eleutherine americana].

OBJECTIVE: To research the chemical constituents from Eleutherine americana. METHODS: Column chromatography with silica gel was employed to isolate and purify the constituents. Their structures were elucidated by means of MS and NMR. RESULTS: Eight constituents were obtained and identified as Isoeleutherol (1), eleutherin (2), isoeleutherin (3), beta-sitosterol(4), 8-hydroxy-3, 4-Dimethoxy-1-methyl-anthra-9, l0-quinone-2-carboxylic acid methyl ester (5), Hongconin (6), 4,8-Dihydroxy-3-Methoxy-1-methyl-anthra-9,10-quinone-2-carboxylic acid methyl ester (7), Eleutherinone (8), Kadsuric acid (9). CONCLUSION: Compound 9 is isolated from the plant for the first time.