RESUMO
We present an efficient and faithful hyperentanglement purification protocol (hyper-EPP) for three-photon system in mixed hyperentangled Greenberger-Horne-Zeilinger states with bit-flip errors in both spatial-mode and polarization degrees of freedom (DOFs), resorting to the fidelity-robust quantum gates and hyperentanglement link. Our high-efficiency hyper-EPP comes from two aspects. One is to pump the higher-fidelity hyperentanglement from different three-photon systems into the same three-photon system with fidelity-robust swap gates, the other is to reproduce some hyperentangled three-photon systems from hyperentangled two-photon subsystems based on hyperentanglement link. Moreover, as the infidelity originating from imperfect single-photon scattering can be heralded as a failure by triggering a detector, our hyper-EPP operates faithfully with the present quantum circuits. Furthermore, our hyper-EPP can be directly extended to purify multiple photon systems entangled in one DOF or hyperentangled in multiple DOFs.
RESUMO
Parkinson's disease (PD) is the second most common neurodegenerative disease, characterized by loss of dopaminergic (DA) neurons in the dense part of the substantia nigra (SNpc). Postmortem analysis of PD patients and experimental animal studies found that microglial cell activation and increased levels of pro-inflammatory factors were common features of PD brain tissue. At the same time, the invasion and accumulation of peripheric immune cells were detected in the brain of PD patients. In this paper, peripheral inflammation across the blood-brain barrier (BBB), the misfolded α-synuclein (α-syn)-induced microglial cell activation and intracerebral inflammation in PD are summarized, providing potential therapeutic measures for delaying the onset of PD.