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1.
Appl Opt ; 63(9): 2167-2174, 2024 Mar 20.
Artigo em Inglês | MEDLINE | ID: mdl-38568568

RESUMO

We report the results of fabricating fiber array unit (FAU) connectors using a near IR laser welding process, locking fibers in proper position on planar glass substrates and forming strong glass-to-glass bonds, followed by final assembly using lower coefficient of thermal expansion (CTE) epoxies. A thin metal film deposited on the glass substrate provides the absorption required to attain interfacial temperatures suitable for glass-to-glass bonding. This method allows the elimination of dedicated expensive V-groove plates while still maintaining very good fiber placement accuracy. The use of epoxy is minimized to simply securing macro packaging components and protecting fibers from environmental pressure, temperature, and humidity variation. The thermal expansion properties of the epoxy used were essential for the long-term FAU reliability.

2.
Lasers Surg Med ; 51(10): 887-896, 2019 12.
Artigo em Inglês | MEDLINE | ID: mdl-31302937

RESUMO

BACKGROUND AND OBJECTIVES: Hospital-acquired infections (HAIs) and multidrug resistant bacteria pose a significant threat to the U.S. healthcare system. With a dearth of new antibiotic approvals, novel antimicrobial strategies are required to help solve this problem. Violet-blue visible light (400-470 nm) has been shown to elicit strong antimicrobial effects toward many pathogens, including representatives of the ESKAPE bacterial pathogens, which have a high propensity to cause HAIs. However, phototherapeutic solutions to prevention or treating infections are currently limited by efficient and nonobtrusive light-delivery mechanisms. STUDY DESIGN/MATERIALS AND METHODS: Here, we investigate the in vitro antimicrobial properties of flexible Corning® light-diffusing fiber (LDF) toward members of the ESKAPE pathogens in a variety of growth states and in the context of biological materials. Bacteria were grown on agar surfaces, in liquid culture and on abiotic surfaces. We also explored the effects of 405 nm light within the presence of lung surfactant, human serum, and on eukaryotic cells. Pathogens tested include Enterococcus spp, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, Enterobacter spp., Staphylococcus epidermidis, Streptococcus pyogenes, Candida albicans, and Escherichia coli. RESULTS: Overall, the LDF delivery of 405 nm violet-blue light exerted a significant degree of microbicidal activity against a wide range of pathogens under diverse experimental conditions. CONCLUSIONS: The results exemplify the fiber's promise as a non-traditional approach for the prevention and/or therapeutic intervention of HAIs. Lasers Surg. Med. © 2019 The Authors. Lasers in Surgery and Medicine Published by Wiley Periodicals, Inc.


Assuntos
Candida albicans/efeitos da radiação , Infecção Hospitalar/prevenção & controle , Desinfecção/métodos , Bactérias Gram-Negativas/efeitos da radiação , Bactérias Gram-Positivas/efeitos da radiação , Lasers Semicondutores/uso terapêutico , Fibras Ópticas , Candidíase/prevenção & controle , Desinfecção/instrumentação , Infecções por Bactérias Gram-Negativas/prevenção & controle , Infecções por Bactérias Gram-Positivas/prevenção & controle , Humanos , Terapia com Luz de Baixa Intensidade , Testes de Sensibilidade Microbiana
3.
Appl Opt ; 42(15): 2683-8, 2003 May 20.
Artigo em Inglês | MEDLINE | ID: mdl-12777003

RESUMO

We describe the performance of a fiber-optic power-limiting component. The passive device is dynamically responsive to the input signal and has been shown to attenuate continuous-wave power with a dynamic range of up to 9 dB at 150 mW of input power at 1550 nm. The limiting threshold is approximately 30 mW from 1530 to 1565 nm and less than 10 mW at 1430 nm. The device is activated by a photothermal defocusing mechanism in an optical polymer fixed between two expanded core fibers that collimate light through the material. The magitude and threshold of the limiting response is dependent on the absorption properties of the polymer and the size of the gap between the two fiber endfaces. Simple model calculations have been made to predict the limiting response, and they agree reasonably well with the performance of the actual device.

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