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Nat Prod Res ; 32(11): 1299-1302, 2018 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-28627304

RESUMO

The aim of this study was to evaluate the ability of 0.1% thyme oil (TO), trans-cinnamaldehyde (TC), ferulic acid (FA), p-coumaric acid (p-CA), caffeic acid (CA), lavender essential oil (LO), geranium essential oil (GO) and tee tree oil (TTO) to control biofilms formed by methicillin-resistant Staphylococcus aureus (MRSA) strains. Depending on the strains, TO reduced 59.7-85% of biofilm mass, while TC 52.9-82.4% after 48 h of treatment. Reduction of metabolic activity of biofilms in ranges 79.3-86% and 85.9-88.7% was observed after 48 h of TC and TO of treatment, respectively. In the case of some strains, reduction of biofilm mass in the presence of FA, CA, GO, LO and TTO was not observed. This study showed that TO and TC might have therapeutic potential as an inhibitory agents for use in MRSA biofilm-related infections.


Assuntos
Antibacterianos/farmacologia , Staphylococcus aureus Resistente à Meticilina/efeitos dos fármacos , Acroleína/análogos & derivados , Acroleína/farmacologia , Antibacterianos/química , Biofilmes/efeitos dos fármacos , Ácidos Cafeicos/farmacologia , Ácidos Cumáricos/farmacologia , Geranium/química , Humanos , Lavandula , Staphylococcus aureus Resistente à Meticilina/isolamento & purificação , Testes de Sensibilidade Microbiana , Óleos Voláteis/química , Óleos Voláteis/farmacologia , Óleos de Plantas/química , Óleos de Plantas/farmacologia , Propionatos , Thymus (Planta)/química
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