RESUMO
The infection of the central nervous system (CNS) by schistosome may or may not have clinical manifestations. When symptomatic, neuroschistosomiasis (NS) is one of the most severe presentations of schistosome infection. Among the NS symptoms, cerebral invasion is mostly caused by Schistosoma japonicum (S. japonicum), and the spinal cord symptoms are mainly caused by S. mansoni or S. haematobium. There are 2 main pathways by which schistosomes cause NS: egg embolism and worm migration, via either artery or vein system, especially the valveless perivertebral Batson's plexus. The adult worm migrates anomalously through the above pathways to the CNS where they lay eggs. Due to the differences in species of schistosomes and stages of infection, mechanisms vary greatly. The portal hypertension with hepatosplenic schistosomiasis also plays an important role in the pathogenesis. Here the pathways through which NS occurs in the CNS were reviewed.
Assuntos
Infecções do Sistema Nervoso Central/complicações , Infecções do Sistema Nervoso Central/parasitologia , Neuroesquistossomose/complicações , Neuroesquistossomose/etiologia , Schistosoma japonicum/patogenicidade , Animais , Infecções do Sistema Nervoso Central/epidemiologia , Interações Hospedeiro-Parasita , Humanos , Neuroesquistossomose/epidemiologia , Neuroesquistossomose/patologiaRESUMO
OBJECTIVE: To investigate the clinical characteristics of intracranial hematoma and the mechanism involved in its rapid natural resolution. METHODS: Seventeen cases of intracranial hematoma with typical clinical and CT manifestations were retrospectively studied. RESULTS: Intracranial hematoma was found obviously decreased in size within 72 h after its occurrence in 8 cases. The rest 9 cases presented complete resolution. CONCLUSIONS: Rapid natural resolution of acute epidural hematoma is mostly found in teenagers and the resolution is correlated with cranial fracture at the hematoma site. As for acute subdural hematoma, its rapid resolution is associated with the transfer of cerebrospinal fluid toward subdural space, the lavage effect, and the compression caused by the increased intracranial pressure or the space left resulting from redistribution of the hematoma in brain atrophy.