A GAN-based genetic algorithm for solving the 3D bin packing problem.

The 3D bin packing problem is a challenging combinatorial optimization problem with numerous real-world applications. In this paper, we present a novel approach for solving this problem by integrating a generative adversarial network (GAN) with a genetic algorithm (GA). Our proposed GAN-based GA utilizes the GAN to generate high-quality solutions and improve the exploration and exploitation capabilities of the GA. We evaluate the performance of the proposed algorithm on a set of benchmark instances and compare it with two existing algorithms. The simulation studies demonstrate that our proposed algorithm outperforms both existing algorithms in terms of the number of used bins while achieving comparable computation times. Our proposed algorithm also performs well in terms of solution quality and runtime on instances of different sizes and shapes. We conduct sensitivity analysis and parameter tuning simulations to determine the optimal values for the key parameters of the proposed algorithm. Our results indicate that the proposed algorithm is robust and effective in solving the 3D bin packing problem. The proposed GAN-based GA algorithm and its modifications can be applied to other optimization problems. Our research contributes to the development of efficient and effective algorithms for solving complex optimization problems, particularly in the context of logistics and manufacturing. In summary, the proposed algorithm represents a promising solution to the challenging 3D bin packing problem and has the potential to advance the state-of-the-art in combinatorial optimization.

Image projective transformation rectification with synthetic data for smartphone-captured chest X-ray photos classification.

Automatic interpretation of chest X-ray (CXR) photos taken by smartphones at the same performance level as with digital CXRs is challenging, due to the projective transformation caused by the non-ideal camera position. Existing rectification methods for other camera-captured photos (document photos, license plate photos, etc.) cannot precisely rectify the projective transformation of CXR photos, due to its specific projective transformation type. In this paper, we propose an innovative deep learning-based Projective Transformation Rectification Network (PTRN) to automatically rectify the projective transformation of CXR photos by predicting the projective transformation matrix. Additionally, synthetic CXR photos are generated for training with the consideration of visual artifacts of natural images. The effectiveness of the proposed classification pipeline with PTRN is evaluated in the CheXphoto smartphone-captured CXR photo classification competition. It achieves first place with a huge performance improvement (ours 0.850, second-best 0.762, in AUC). Moreover, experimental results show that our approach successfully achieves the same performance level of digital CXR classification (AUC 0.893) on CXR photo classification (AUC 0.893).

DMNet: A Personalized Risk Assessment Framework for Elderly People With Type 2 Diabetes.

Type 2 diabetes is the most common chronic disease for the elderly people. This disease is difficult to be cured and causes continued medical expenses. The early and personalized risk assessment of type 2 diabetes is necessary. So far, various type 2 diabetes risk prediction methods have been proposed. However, these methods have three major issues: 1) not fully considering the importance of personal information and rating information of healthcare system, 2) not adopting the long-term temporal information, and 3) not comprehensively capturing the correlation between the diabetes risk factor categories. To address these issues, the personalized risk assessment framework for elderly people with type 2 diabetes is needed. However, it is very challenging due to two reasons, namely imbalanced label distribution and high-dimensional features. In this paper, we propose diabetes mellitus network framework (DMNet) for type 2 diabetes risk assessment of elderly people. Specifically, we propose tandem long short-term memory to extract the long-term temporal information of different diabetes risk categories. In addition, the tandem mechanism is used to capture the correlation between the diabetes risk factor categories. To balance the label distribution, we adopt the method of synthetic minority over-sampling technique with Tomek links. To form the better feature representations, we utilize entity embedding to solve the problem of high-dimensional features. To evaluate the performance of our proposed method, we conduct the experiments on a real-world dataset called Research on Early Life and Aging Trends and Effects. The experiment results show that DMNet outperforms the baseline methods in terms of six evaluation metrics (i.e., accuracy of 0.94, balanced accuracy of 0.94, precision of 0.95, F1-score of 0.95, recall of 0.95 and AUC of 0.94).

DeSeg: auto detector-based segmentation for brain metastases.

Delineation of brain metastases (BMs) is a paramount step in stereotactic radiosurgery treatment. Clinical practice has specific expectation on BM auto-delineation that the method is supposed to avoid missing of small lesions and yield accurate contours for large lesions. In this study, we propose a novel coarse-to-fine framework, named detector-based segmentation (DeSeg), to incorporate object-level detection into pixel-wise segmentation so as to meet the clinical demand. DeSeg consists of three components: a center-point-guided single-shot detector to localize the potential lesion regions, a multi-head U-Net segmentation model to refine contours, and a data cascade unit to connect both tasks smoothly. Performance on tiny lesions is measured by the object-based sensitivity and positive predictive value (PPV), while that on large lesions is quantified by dice similarity coefficient (DSC), average symmetric surface distance (ASSD) and 95% Hausdorff distance (HD95). Besides, computational complexity is also considered to study the potential of method in real-time processing. This study retrospectively collected 240 BM patients with Gadolinium injected contrast-enhanced T1-weighted magnetic resonance imaging (T1c-MRI), which were randomly split into training, validating and testing datasets (192, 24 and 24 scans, respectively). The lesions in the testing dataset were further divided into two groups based on the volume size (smallS: ≤1.5 cc,N= 88; largeL: > 1.5 cc,N= 15). On average, DeSeg yielded a sensitivity of 0.91 and a PPV of 0.77 on S group, and a DSC of 0.86, an ASSD 0f 0.76 mm and a HD95 of 2.31 mm onLgroup. The results indicated that DeSeg achieved leading sensitivity and PPV for tiny lesions as well as segmentation metrics for large ones. After our clinical validation, DeSeg showed competitive segmentation performance while kept faster processing speed comparing with existing 3D models.