The Derivation of Epigastric Motion to Assess Neonatal Breathing and Sleep: An Exploratory Study.

INTRODUCTION: New non-medical monitors are offered for respiration monitoring of neonates. Epigastric motion during sleep was investigated by means of a wearable tracker in parallel to clinical monitoring. COHORT: 23 hospitalised neonates ready for discharge. METHODS: A 3-axes-accelerometer and -gyroscope was placed in a standard epigastric position. Between two routine care rounds signals were recorded in parallel to monitoring of impedance pneumography (IP), ECG and pulse oximetry. Motion signals vs. time charts were evaluated using 10-min episodes and semiquantitatively assigned to breathing signal quality, regular breathing, periodic breathing and confounding artefacts. The results were compared with the impedance pneumographic data. RESULTS: 26 recordings (mean duration: 210 min/infant) were conducted without bradycardia or apnea alarm. The gestational age at birth ranged 28.9 to 41.1 and at recording from 35.6 to 42.3 postmenstrual weeks. Motion patterns of quiet sleep with regular breathing, periodic breathing and active sleep with confounding body movements were found. The longitudinal and transversal gyroscope axes resulted in best signal quality. Periodic breathing was found in up to 80% of episodes and decreased inversely with gestational age showing significantly more periodic breathing in preterm infants. Respiration signals of the gyroscope vs. IP showed a low bias and highly variating frequencies. CONCLUSIONS: Standardized motion trackers may detect typical neonatal breathing and body-motion-patterns, that could help to classify neonatal sleep. Respiratory rates can only be determined during quiet sleep.

Direct multi-dimensional Chebyshev polynomial based reconstruction for magnetic particle imaging.

Magnetic Particle Imaging is a tomographic imaging technique that measures the voltage induced due to magnetization changes of magnetic nanoparticle distributions. The relationship between the received signal and the distribution of the nanoparticels is described by the system function. A common method for image reconstruction is using a measured system function to create a system matrix and set up a regularized linear system of equations. Since the measurement of the system matrix is time-consuming, different methods for acceleration have been proposed. These include modeling the system matrix or using a direct reconstruction method in time, known as X-space reconstruction. In this work, based on the simplified Langevin model of paramagnetism and certain approximations, a direct reconstruction technique for Magnetic Particle Imaging in the frequency domain with two- and three-dimensional Lissajous trajectory excitation is presented. The approach uses Chebyshev polynomials of second kind. During reconstruction, they are weighted with the frequency components of the voltage signal and additional factors and then summed up. To obtain the final nanoparticle distribution, this result is rescaled and deconvolved. It is shown that the approach works for both simulated data and real measurements. The obtained image quality is comparable to a modeled system matrix approach using the same simplified physical assumptions and no relaxation effects. The reconstruction of a 31 × 31 × 31 volume takes less than a second and is up to 25 times faster than the state-of-the-art Kaczmarz reconstruction. Besides, the derivation of the proposed method shows some new theoretical aspects of the system function and its well-known observed similarity to tensor products of Chebyshev polynomials of second kind.

sEMG-Based Hand Movement Regression by Prediction of Joint Angles With Recurrent Neural Networks.

This work takes a step towards a better biosignal based hand gesture recognition by investigating the strategies for a reliable prediction of hand joint angles. Those strategies are especially important for medical applications in order to achieve e.g. good acceptance of hand prostheses among amputees. A recurrent neural network with a small footprint is deployed to estimate the joint positions from surface electromyography data measured at the forearm. As the predictions are expected to be not smooth, different post processing methods and a regularisation term for the objective function of the network are proposed. The experiments were conducted on publicly available databases. The results reveal that both post processing strategies and regularisation have a positive impact on the results with a maximal relative improvement of 6.13 %. On the one hand post processing strategies introduce an additional delay, consequently, the improvement is analysed in context of the caused delay. On the other hand the regularisation strategy does not cause a delay and can be adjusted easily to cope with different ground truths or compensate for certain problems in the hand tracking.

Regression of Hand Movements from sEMG Data with Recurrent Neural Networks.

Most wearable human-machine interfaces concerning hand movements only focus on classifying a limited number of hand gestures. With the introduction of deep learning, surface electromyography based hand gesture classification systems improved drastically. Therefore, it is worth investigating whether the classification can be replaced by a movement regression of all the different movable hand parts. As recurrent neural networks based approaches have proven their abilities of solving the classification problem we also choose them for the regression problem. Experiments were conducted with multiple different network architectures on several databases. Furthermore, due to the lack of a reliable measure to compare different gesture regression approaches we propose an interpretable and reproducible new error measure that can even handle noisy ground truth data. The results reveal the general possibility of regressing detailed hand movements. Even with the relatively simple networks the hand gestures can be regressed quite accurately.

Multiresolution vessel detection in magnetic particle imaging using wavelets and a Gaussian mixture model.

PURPOSE: Magnetic particle imaging is a tomographic imaging technique that allows one to measure the spatial distribution of superparamagnetic nanoparticles, which are used as tracer. The magnetic particle imaging scanner measures the voltage induced due to the nonlinear magnetization behavior of the nanoparticles. The tracer distribution can be reconstructed from the voltage signal by solving an inverse problem. A possible application is the imaging of vessel structures. In this and many other cases, the tracer is only located inside the structures and a large part of the image is related to background. A detection of the tracer support in early stages of the reconstruction process could improve reconstruction results. METHODS: In this work, a multiresolution wavelet-based reconstruction combined with a segmentation of the foreground structures is performed. For this, different wavelets are compared with respect to their reconstruction quality. For the detection of the foreground, a segmentation with a Gaussian mixture model is performed, which leads to a threshold-based binary segmentation. This segmentation is done on a coarse level of the reconstruction and then transferred to the next finer level, where it is used as prior knowledge for the reconstruction. This is repeated until the finest resolution is reached. RESULTS: The approach is evaluated on simulated vessel phantoms and on two real measurements. The results show that this method improves the structural similarity index of the reconstructed images significantly. Among the compared wavelets, the 9/7 wavelets led to the best reconstruction results. CONCLUSIONS: The early detection of the vessel structures at low resolution helps to improve the image quality. For the wavelet decomposition, the use of 9/7 wavelets is recommended.

A Recurrent Neural Network for Hand Gesture Recognition based on Accelerometer Data.

For many applications, hand gesture recognition systems that rely on biosignal data exclusively are mandatory. Usually, theses systems have to be affordable, reliable as well as mobile. The hand is moved due to muscle contractions that cause motions of the forearm skin. Theses motions can be captured with cheap and reliable accelerometers placed around the forearm. Since accelerometers can also be integrated into mobile systems easily, the possibility of a robust hand gesture recognition based on accelerometer signals is evaluated in this work. For this, a neural network architecture consisting of two different kinds of recurrent neural network (RNN) cells is proposed. Experiments on three databases reveal that this relatively small network outperforms by far state-of-the-art hand gesture recognition approaches that rely on multi-modal data. The combination of accelerometer data and an RNN forms a robust hand gesture classification system, i.e., the performance of the network does not vary a lot between subjects and it is outstanding for amputees. Furthermore, the proposed network uses only 5 ms short windows to classify the hand gestures. Consequently, this approach allows for a quick, and potentially delay-free hand gesture detection.

Recurrent Neural Network Based Early Prediction of Future Hand Movements.

This work focuses on a system for hand prostheses that can overcome the delay problem introduced by classical approaches while being reliable. The proposed approach based on a recurrent neural network enables us to incorporate the sequential nature of the surface electromyogram data and the proposed system can be used either for classification or early prediction of hand movements. Especially the latter is a key to a latency free steering of a prosthesis. The experiments conducted on the first three Ninapro databases reveal that the prediction up to 200 ms ahead in the future is possible without a significant drop in accuracy. Furthermore, for classification, our proposed approach outperforms the state of the art classifiers even though we used significantly shorter windows for feature extraction.

Early prediction of future hand movements using sEMG data.

We study in this work the feasibility of early prediction of hand movement based on sEMG signals to overcome the time delay issue of the conventional classification. Opposed to the classification task, the objective of early prediction is to predict a hand movement that is going to occur in the future given the information up to the current time point. The ability of early prediction may allow a hand prosthesis control system to compensate for the time delay and, as a result, improve the usability. Experimental results on the Ninapro database show that we can predict up to 300 ms ahead in the future while the prediction accuracy remains very close to that of the standard classification, i.e. it is just marginally lower. Furthermore, historical data prior the current time window is shown to be very important to improve performance, not only for the prediction but also the classification task.

Sound-field measurement with moving microphones.

Closed-room scenarios are characterized by reverberation, which decreases the performance of applications such as hands-free teleconferencing and multichannel sound reproduction. However, exact knowledge of the sound field inside a volume of interest enables the compensation of room effects and allows for a performance improvement within a wide range of applications. The sampling of sound fields involves the measurement of spatially dependent room impulse responses, where the Nyquist-Shannon sampling theorem applies in the temporal and spatial domains. The spatial measurement often requires a huge number of sampling points and entails other difficulties, such as the need for exact calibration of a large number of microphones. In this paper, a method for measuring sound fields using moving microphones is presented. The number of microphones is customizable, allowing for a tradeoff between hardware effort and measurement time. The goal is to reconstruct room impulse responses on a regular grid from data acquired with microphones between grid positions, in general. For this, the sound field at equidistant positions is related to the measurements taken along the microphone trajectories via spatial interpolation. The benefits of using perfect sequences for excitation, a multigrid recovery, and the prospects for reconstruction by compressed sensing are presented.