Large Cheek Defect Reconstruction With a Rhomboid Flap and Burow's Advancement Flap After Excision of a Basal Cell Carcinoma. / Reconstrucción de un defecto en mejilla tras la exéresis de un carcinoma basocelular extenso mediante la combinación de un colgajo romboidal y un injerto de Burow.

Reconstruction of large surgical defects on the cheek can be challenging for dermatologic surgeons. We describe using a modified rhomboid flap and Burow's advancement flap to close a surgical defect resulting from the excision of a basal cell carcinoma measuring 10×10cm in the buccomandibular area of the cheek.

Aporte de fluidos en el pacientes pediátricos hospitalizados / Fluid intake in hospitalized pediatric patients

El aporte de fluidos constituye un elemento central en la atención del paciente pediátrico hospitalizado, existiendo aún controversias acerca de cuál es la composición óptima, la dosis adecuada y la mejor estrategia para administrar los mismos. El propósito de este artículo de actualización es brindar al médico que se desempeña en las diferentes áreas de la internación pediátrica, conceptos y enfoques terapéuticos que lo ayuden en la asistencia de los pacientes que por diversos motivos requieren la administración de fluidos endovenosos. La recomendación de utilizar cristaloides en la reanimación es casi uniforme. Se observa una clara tendencia al uso de soluciones isotónicas balanceadas para la reposición del déficit previo y el aporte de fluidos de mantenimiento. En relación a la dosis y a la estrategia, es generalizada la recomendación de un enfoque más restrictivo en el aporte de volumen, aún en los pacientes con shock, donde es necesario lograr un balance entre una resucitación efectiva y el riesgo de sobrecarga de fluidos. Respecto a la administración de albúmina al 20% en el paciente crítico con hipoalbuminemia, la evidencia existente es escasa y no permite formular recomendaciones. Sin embargo, es frecuente su uso en la práctica asistencial

Intravenous fluids administration is a central element in the care of hospitalized pediatric patients, and there are still controversies about what is the optimal composition, the appropriate dose, and the best strategy for their administration. The purpose of this narrative review is to provide the physicians who works in the different areas of pediatric hospitalization, concepts and therapeutic approaches that help them in the care of patients who for diverse reasons require administration of intravenous fluids. The recommendation to use crystalloids in resuscitation is almost uniform. There is a clear trend towards the use of balanced isotonic solutions to replace the previous deficit and the supply of maintenance fluids. In relation to the dose and strategy, the recommendation of a more restrictive approach in volume administration is generalized, even in patients with shock, where it is necessary to strike a balance between effective resuscitation and the risk of fluid overload. Regarding the administration of 20% albumin in critically ill patients with hypoalbuminemia, the existing evidence is scarce and does not allow recommendations to be formulated. However, it is frequently used in healthcare practice

Modified keystone flap used to repair nose defect after Mohs micrographic surgery.

Mohs micrographic surgery (MMS) is a surgical technique used to remove skin tumors with a complete evaluation of the margins. The keystone flap technique is generally used to repair large surgical defects on limbs. We present a case where a modified keystone flap technique was used to close a large defect after Mohs micrographic surgery in a patient with a basal cell carcinoma on the nose. An excellent functional and aesthetic result was obtained with no complications during or after the procedure. We offer a novel indication for this technique for surgical defects in this area.

Tissue-Sparing Outcome of Mohs Micrographic Surgery in Squamous Cell Carcinomas. / Ahorro de tejido tras la cirugía micrográfica de Mohs en los carcinomas de células escamosas.

BACKGROUND: Micrographic Mohs Surgery (MMS) offers the highest cure rates and healthy skin tissue sparing effect compared with standard excision. OBJECTIVE: To quantify the tissue-sparing properties of MMS in squamous cell carcinoma (SCC) in comparison with standard excision (SE). METHODS: A bidirectional, descriptive study, including 94 cases of SCC, was performed, on patients with histologic diagnosis of SCC (in situ, well differentiated, moderately differentiated, and undifferentiated), that where operated with MMS between 2013 and 2018 at Hospital de Clínicas Dr. Manuel Quintela in Montevideo, Uruguay. Tumor size and defect area after MMS were measured in 2 perpendicular directions. The suspected defect area was calculated with standard excision using a 4-mm margin for low risk lesions and a 10-mm margin for high risk lesions. The primary outcome of this study was the size of the defect area post MMS compared with the calculated defect area with standard excision. RESULTS: The median tumor size was 1,41mm2, and the median defect size after MMS was 4,12mm2. The median defect size calculated for standard surgical excision was 8,36mm2. LIMITATIONS: We do not use all National Comprehensive Cancer Network (NCCN) criteria. We define low and high risk lesions just taking into account anatomical location, size, histopathology and whether it was a primary or recurrent tumor. CONCLUSION: Our results show that MMS has a tissue-sparing effect of at least 52% compared to SE.

East-West Flap After Mohs Micrographic Surgery. / Colgajo este-oeste después de la cirugía micrográfica de Mohs.

Repair of distal nasal defects resulting from Mohs micrographic surgery is a challenge, but surgeons can choose from a number of techniques. We present 3 cases in which an east-west flap was used to close the defect. The east-west flap is an easily conceived advancement flap that consists of a superior triangle used to cover the defect and an inferior triangle whose base is located along the advancement line. The flap results in an optimal cosmetic outcome and involves minimum movement of tissue (preserving the nasal architecture) and well-camouflaged suture lines.

The Super Shaving Technique to Correct the Trapdoor Effect in Nasal Flaps. / Afeitado profundo (super shaving) para la corrección del efecto en trampilla de colgajos nasales.

INTRODUCTION AND OBJECTIVES: The trapdoor effect is a possible complication in flap reconstructions, particularly those involving the face. It consists of a bulging, elevated deformity that appears 3 weeks after the intervention. To date there has been no consensus on how the trapdoor effect should be treated. The aim of this article is to report on our experience with this defect and describe how we use the 'super shaving' technique to resolve the trapdoor effect in nasal flaps. MATERIAL AND METHODS: We performed a retrospective, descriptive study of 10 patients who developed a bulging deformity of a nasal flap that was treated surgically with the super shaving technique. We also report on postoperative management. RESULTS: The median age of the 10 patients was 67.7 years and they all developed a bulging transposition flap in the nasal area after conventional or Mohs micrographic surgery. The complication occurred approximately 5 weeks after surgery and healing time was 4 weeks. There were no major postoperative complications and the outcome was of low aesthetic significance compared with the bulging flap. All the patients stated they were very satisfied with the aesthetic outcome. CONCLUSIONS: In our opinion, the super shaving technique is a fast, effective, simple, and cheap outpatient procedure that offers excellent aesthetic results.

Reconstructive methods in Mohs micrographic surgery in Uruguay: A bidirectional descriptive cohort analysis.

BACKGROUND AND OBJECTIVES: The primary goal of Mohs micrographic surgery (MMS) is to completely excise a cancerous lesion and a wide range of reconstructive techniques of varying complexity are used to close the resulting wound. In this study, we performed a descriptive analysis of patients who underwent MMS, with a focus on wound closure methods. MATERIAL AND METHODS: We conducted a bidirectional descriptive cohort analysis of all MMS procedures performed by a single surgeon between November 2013 and April 2016. Cosmetic outcomes were photographically assessed by a dermatologist after a minimum follow-up of 90 days. RESULTS: We analyzed 100 MMS procedures in 71 patients with a median age of 73 years. The tumors were basal cell carcinoma (70%), squamous cell carcinoma (29%), and dermatofibrosarcoma protuberans (1%); 75% were located on the head and neck. The reconstructive techniques used were flap closure (48%), simple closure (36%), closure by second intention (11%), and other (5%). Cosmetic outcomes were assessed for 70 procedures (47 patients) and the results were rated as excellent in 20% of cases, very good in 40%, good in 20%, moderate in 17%, and bad/very bad in 2.9%. No significant associations were observed between cosmetic outcome and sex, Fitzpatrick skin type, hypertension, diabetes mellitus, or smoking. Worse outcomes, however, were significantly associated with larger tumor areas and defects, location on the trunk, and flap and second-intention closure. CONCLUSIONS: Although there was a tendency to use simple wound closure for lesions located on the trunk and surgical defects of under 4.4cm2, the choice of reconstructive technique should be determined by individual circumstances with contemplation of clinical and tumor-related factors and the preference and experience of the surgeon.

Super U Technique for Ingrown Nails. / Exéresis en U para la onicocriptosis.

INTRODUCTION AND OBJECTIVES: Ingrown nails are a common problem, seen mostly in young adults. Also known as onychcrypotisis, this condition typically affects the great toenail. Four stages have been defined according to the severity and duration of the condition, and treatment varies from conservative to surgical techniques depending on the stage. We present our experience with this condition, describing the characteristics of our population and surgical treatment, in particular the super U technique. MATERIAL AND METHODS: This was a retrospective, descriptive study of patients with ingrown great toenail treated surgically using the super U technique. We also describe postoperative management. RESULTS: Ten patients with a mean age of 35.7 years underwent operation, 9 for unilateral ingrown great toenail and 1 for bilateral disease. Stage II ingrown nail was the most common. Half of the patients had been treated previously using other surgical techniques. The mean time to healing was 6 weeks. The only postoperative complication was infection in 1 patient. Mild to moderate postoperative pain persisted for a week. The majority of patients were satisfied with the cosmetic result. CONCLUSIONS: We believe the super U technique is very useful in stage II ingrown nail and in disease that has recurred after previous surgery, and is the treatment of choice in stage III or IV disease in which excessive hypertrophic tissue is found.

Dermoscopy of Disseminated Superficial Actinic Porokeratosis.

We present a series of 6 cases of disseminated superficial actinic porokeratosis and describe their dermoscopic features. Dermoscopy is a noninvasive in vivo technique that is useful as a tool for the diagnosis and follow-up of porokeratosis. This condition has specific dermoscopic features that were observed in our series of cases and that are consistent with reports in the international literature.

Dermoscopic patterns of 158 acral melanocytic nevi in a Latin American population.

BACKGROUND: Melanocytic nevi are frequently found on acral volar skin. Differentiation between nevi and melanoma is essential and sometimes difficult, although dermoscopy has enabled a more specific diagnosis of pigmented lesions. Dermoscopic patterns of lesions on acral volar skin have mostly been described in European and Asian populations. The Latin American population is heterogeneous, and particularly so in the case of Uruguayans, who largely descend from 3 distinct populations. OBJECTIVE: To describe dermoscopic patterns of acral melanocytic nevi and evaluate their applicability in a Latin American population in Uruguay. PATIENTS AND METHODS: This was an observational, descriptive, cross-sectional study conducted by 2 dermatologists from 4 dermatology clinics in Uruguay. Uruguayan patients older than 18 years with acral melanocytic nevi were included. Digital dermoscopic images were captured and jointly analyzed by 2 investigators. RESULTS: A total of 158 acral volar nevi in 80 patients were analyzed. The most-prevalent pattern was the parallel furrow pattern (51.3% of nevi), followed by the latticelike pattern (13.3%), the homogeneous pattern (12.7%), the globular pattern (9.5%), the fibrillar pattern (7%), the globulostreaklike pattern (3.8%), and the nontypical pattern (2.5%). The reticular and transition patterns were not observed in our population. CONCLUSIONS: The parallel furrow pattern, followed by the latticelike and homogeneous patterns, was the most-prevalent pattern in acral melanocytic nevi in the Uruguayan population. The fibrillar pattern was found exclusively on the soles. No new dermoscopic patterns were observed. The patterns described in Asian and European literature apply to our population.

Monitoreo hemodinámico funcional en cirugía cardiovascular pediátrica bajo circulación extracorpórea / Hemodynamic monitoring Functional in surgery low pediatric cardiovascular Extracorporeal circulation

El síndrome de respuesta inflamatoria sistémica es una complicación frecuente en el período posoperatorio cardiovascular. Su gravedad es variable y múltiples factores generan una disfunción endotelial que se expresa de diferentes formas en la hemodinamia del paciente, ya sea con cuadros clínicos similares al shock frío o al shock caliente, según el mecanismo fisiológico predominante. Utilizamos un método de monitoreo mínimamente invasivo, configurando perfiles hemodinámicos basales e inducidos por fármacos, de tal modo de realizar un manejo racional de agentes vasoactivos. El propósito de este trabajo es mostrar la aplicación del monitoreo hemodinámico funcional, graficar la variabilidad de la hemodinamia en el período posquirúrgico y evidenciar la respuesta clínica al azul de metileno. Para tal fin, se presenta a modo de ejemplo un paciente con shock vasopléjico.(AU)

Cardiac surgery with cardiopulmonary bypass in children is associated with a systemic inflammatory response syndrome of different degree. The endothelial dysfunction may be followed by acute circulatory dysfunction that results in different hemodynamic profiles like cold or warm shock. Hemodynamic variables were measured with a minimal invasive method of hemodynamic monitoring and they were grouped in order to define profiles and evaluate the response to therapy. The goal of this work is to describe the functional hemodynamic monitoring in the care of pediatric cardiac surgery patients through the presentation of a child with vasodilatory shock and his response to the administration of methylene blue.(AU)

Anticoagulación en niños cardiópatas / Anticoagulation in children heart disease

Las enfermedades tromboembólicas han sido denominadas la nueva epidemia de los hospitales pediátricos del tercer nivel de atención. Son más evidentes en los pacientes cardíacos y cardioquirúrgicos que en ningún otro tipo de enfermos. Los niños tratados por cardiopatía estructural desarrollan trombosis iatrogénicamente, con frecuencia, precipitada por un catéter venoso central. El sistema de la hemostasia no está completamente desarrollado hasta los 6 meses de vida. Hay importantes diferencias fisiológicas en el sistema hemostático de los niños comparado con el de los adultos. Las complicaciones trombóticas en niños son habitualmente eventos secundarios asociados a patologías subyacentes. La incidencia global de eventos tromboembólicos en niños está aumentando, se estima que oscila entre 0,07 y 28,8 casos por cada 10.000 admisiones pediátricas en general. Este artículo revisa determinados procesos mórbidos pediátricos, los agentes antitrombóticos administrados con más frecuencia a la población pediátrica y la evidencia científica disponible para la prevención ante diferentes situaciones clínicas.(AU)

Tromboembolic disease has been termed the new epidemic of pediatric tertiary care hospitals. This is more evident in cardiac and cardiac surgical patients than in any other type of patients. Children treated for congenital structural cardiac disease develop iatrogenic thrombosis, most commonly precipitated by central venous access. The hemostatic system is not fully mature by 6 months of age. There are important physiologic differences in the hemostatic system in children compared with adults. Thrombotic complications, when they occur in children, are usually secondary events related to serious underlying disorders. The overall incidence of venous thromboembolism events in children is increasing, with estimates ranging from 0.07 to 28.8 per 10,000 in general pediatric admissions. This article reviews a number of specific pediatric cardiac conditions, the common antithrombotic agents used in pediatrics, and the current evidence for prevention in different clinical situations(AU)

Goal coordination in narrative comprehension.

In this paper, we report two experiments in which the consequence of maintaining multiple, unrelated character goals during comprehension were studied. This is in contrast to previous work that has focused on a single goal, or multiple related goals. The results showed that the presence of active subsequent goals can diminish the availability of earlier mentioned goals, even in the absence of semantic and other relations. In contrast, the status of earlier mentioned goals does not influence the availability of subsequent goals. These results support an explanation-based view of comprehension.