Comprehension of Cochlear Duct Length for Incomplete Partition Types.

OBJECTIVE: Preoperative assessment of the cochlear duct length (CDL) and cochlear dimensions allows the selection of optimized implants. We aimed to evaluate the CDL measurements in incomplete partition (IP) defect patients and to create a reference to the literature. METHODS: Forty-one patients with IP (13 IP I, 23 IP II, and 5 IP III) and 30 controls were included in the study. The standardized cochlear image showing the basal turn in the most expansive plane was reconstructed from temporal high-resolution computed tomography images. Cochlear duct length measured manually (CDL-M) was measured by points placed consecutively on the lateral wall of the cochlea. The defined equations for estimating CDL (CDL measured according to Schurzig et al formula [CDL-Ɵ], CDL measured according to Escudé et al formula [CDL-E], CDL measured according to Alexiades et al formula [CDL-A]) were calculated from the same images. Cochlear duct length mean values obtained by each method were compared for each IP type. RESULTS: The longest CDL value was found in the control group, irrespective of the calculation method. Incomplete partition II cases had the most extended mean CDL among IP types. Incomplete partition III had the shortest CDL among all groups' CDL-M values. However, the mean CDL-M values of IP types I and III showed close results. There was no significant difference between the CDL-E and CDL-M values of the control group. Similarly, no significant difference was found between CDL-Ɵ and CDL-M values in IP type III cases. However, the results of other estimating formulations of all groups differed significantly from CDL-M values. CONCLUSION: Cochlear duct length differences were detected between the control group and IP subtypes. These differences should be considered when choosing the appropriate electrode length. Because the results of formulas estimating CDL may differ from CDL-M in both control and IP cases, it would be more appropriate to use manual measurements in clinical practice.

The Cochlear Size Variations in Incomplete Partitions with Multiplanar Images on Pediatric Temporal Bone CT.

Objectives: The purpose of the study was to evaluate cochlea dimensions by the multiplanar reconstruction of high-resolution computed tomography that could be useful in diagnosing incomplete partition (IP) malformations. Methods: This study included 32 patients with 64 side cochleae diagnosed with IP defect and 38 cochleae as the control without any defect. Basal turn length (BL), cochlear height (CH), Mid-apical length (MAL), Mid-apical height, Cochlear length (A), and Cochlear width (B) were measured on reformat images. Results: Twenty cochleae of these patients have been diagnosed with IP type I, 34 with IP type II, and 10 with IP type III. The MAL values are shorter than the control group in IP types I and III (p<0.001, p<0.001). BL values are shorter in IP type III cases (p<0.001). In IP II cases, BL and MAL values overlapped with the control group. CH did not differ significantly from the control group in any IP type. A and B values were significantly lower than the control group for IP I and III (p<0.01). There is a positive correlation between A and B values for all IP types (p<0.01). Conclusion: Quantitative data about differences in the size and shape of the cochlea in IP cases would help differentiate them from the normal cochlea. Since A and B values showed a positive correlation, it is suggested that A and B values can be used to estimate CDL for IP types.

The effect of radiofrequency ablation on pain score and non-steroidal painkiller use in osteoid osteoma patients.

AIM: CT-guided radiofrequency ablation (RFA) is among the thermal ablative procedures and provides great benefits with a minimally invasive procedure. In this prospective study, we aimed to reveal the significance of a multidisciplinary method in reducing the recurrence and complications in osteoid osteoma patients with CT-guided RFA performed by a team of experts in the field. MATERIALS AND METHODS: A total of consecutive 40 patients with osteoid osteoma were prospectively evaluated and treated with CT-guided RFA. Before and the post ablation the visual analog scale (VAS) and use of nonsteroidal anti-inflammatory drugs (NSAIDS) were compared. RESULTS: Post-ablation VAS of the patients at the 1st week and 3rd month after the procedure decreased significantly (p < 0.01) compared to the pre-ablation. The frequency of NSAID use after the ablation decreased significantly (p < 0.01) compared to the pre-ablation time. The pre-procedure NSAID use of our patients included in the study was average 6.93 per week, the NSAID use in the 3rd month post-procedure controls was average 0.53 per week. Recurrence was detected in 4 of our patients, 36 patients had complete recovery. CONCLUSION: Radiofrequency ablation is an effective treatment method in the management of osteoid osteomas. Radiofrequency ablation has low recurrence rates and provides rapid regression in patients' pain after treatment.

Diffusion Tensor Imaging of Auditory Pathway: A Comparison of Pediatric Cochlear Implant Candidates and Healthy Cases.

BACKGROUND: We aimed to investigate the changes that may occur in the auditory neural network in pediatric congenital hearing loss cases. METHODS: Fifty-four cochlear implant candidates and 47 normal-hearing controls were included in this retrospective study. Fractional anisotropy, radial diffusivity, and apparent diffusion coefficient maps were generated. We placed region of interest on the cochlear nucleus, superior olivary nucleus, lateral lemniscus, medial geniculate body, auditory radiation, Heschl's gyrus, inferior fronto-occipital fasciculus, superior longitudinal fascicle, and corpus callosum splenium. The area of the cochlear nerve was measured. Diffusion tensor imaging metrics, children's ages, and cochlear nerve area were compared. RESULTS: Apparent diffusion coefficient and radial diffusivity values of patients were higher than the control group in all places except the radial diffusivity values of medial geniculate body. The fractional anisotropy values of the patients in lateral lemniscus, auditory radiation, Heschl's gyrus, inferior fronto-occipital fasciculus, superior longitudinal fascicle, and corpus callosum splenium were lower than the control group. There is a positive correlation between fractional anisotropy and age in both patient and control groups for all locations. The cochlear nerve area is lower in patients (0.88 ± 0.29) than in the control group (1.18 ± 0.14) (P = .000). The cochlear nerve area has a positive correlation with age in the patient group (P = .000) but has not in the control group. The cochlear nerve area positively correlates with fractional anisotropy values of all locations except fractional anisotropy values of medial geniculate body. CONCLUSION: The alterations of diffusion tensor imaging metrics on the auditory pathway reflect the microstructural changes of white matter tracts.

Olfactory bulb volume in cochlear implant candidates as compared to age-matched control subjects: A potential marker of cognitive function for auditory information processing.

OBJECTIVE: To evaluate magnetic resonance imaging (MRI)-based olfactory bulb (OB) volumes in cochlear implant (CI) candidates with sensorineural hearing loss as compared to age-matched control subjects with normal hearing. METHODS: A total of 31 pediatric CI candidates (mean ± SD age: 7.0 ± 2.5 years, 51.6% were boys) with sensorineural hearing loss and 35 age-matched control subjects (mean ± SD age: 7.1 ± 2.5 years, 54.3% were boys) with normal hearing were included in this study. Data on demographic characteristics (age, gender) and right and left OB volume (mm3) on MRI using planimetric contouring method were recorded in patients and control groups. RESULTS: Median (min-max) values for right OB volume (80(50-120) vs. 90(50-160) mm3, p = 0.006) and left OB volume (70(50-120) vs. 90(50-170) mm3, p = 0.007) were significantly lower in CI candidates vs. controls, regardless of the gender and age. No significant difference was noted between right and left OB volume in CI candidate and control groups. Hearing loss subgroups of CI candidates including hereditary familial (n = 8), hereditary non-familial (n = 14) and mixed syndromic (9) subgroups were also similar in terms of patient demographics and OB volumes. There was a tendency for having lower left OB volume (60(50-120) vs. 80(60-110) mm3) in girls vs. boys in the CI candidate group, along with a tendency for lower left and right OB volume in candidates vs. controls, particularly at age 11 (median 120 vs. 80 mm3 and 120 vs. 60 mm3, respectively). No significant correlation of age was noted with right and left OB volume overall and in the study groups. CONCLUSION: In conclusion, our findings revealed lower left and right OB volumes in CI candidates compared to control subjects, regardless of age and gender, indicating the presence of baseline olfactory dysfunction in patients with hearing loss planned to undergo CI. Accordingly, MRI-based measurement of OB volume in the pre-surgical workup of CI candidates may serve as a marker of cognitive function enabling auditory information processing that may also correlate with post-operative CI outcomes.

Do the Age of Implantation, the Widths of Internal Acoustic Canal and Bony Cochlear Nerve Canal Affect the Auditory Performance of Primary School Children with Bilateral Cochlear Implants?

Objective: To reveal the correlation between implantation age, the internal acoustic canal (IAC) width, bony cochlear nerve canal (BCNC) width, and auditory performance in primary school children with bilateral cochlear implantation (CI). Methods: Preoperative IAC and BCNC widths of 57 pre-lingually deaf children aged 7-11 years who had previously undergone bilateral CI in our institution were reviewed and cut-off values were calculated. Twenty-four patients who had additional problems and could not attend school and those who refused to participate in the study were excluded. The remaining 33 were invited to the hospital, and their speech perception tests, and language development scores were analyzed (16 of 33 patients had been operated on before the age of 24 months). Results: The cut-off values calculated from the 114 ears of 57 patients were 3.86 mm for IAC width and 1.56 mm for BCNC width. The auditory performances of the 33 patients after CI were not significantly different in the narrow and normal width groups. However, speech perception test results, and language development scores of patients implanted before the age of 24 months were significantly higher. Conclusion: There are some studies showing that children with bilateral sensorineural hearing loss have narrower IAC and BCNC widths. However, we concluded that the widths of the IAC and the bone cochlear nerve canal did not affect auditory performance. We found that implantation age is the single most important determinant of speech-language development after CI.

Ethmoid roof morphometric measurements of a pediatric population using computed tomography.

OBJECTIVE: To reveal the anatomical relationships of the ethmoid roof on CT in pediatric case group. METHODS: We measured the depth of olfactory fossa (DOF), the width of olfactory fossa (WOF), the angle between lateral lamella and cribriform plate (LLCPA), the width of the olfactory cleft (WOC), the length of lateral lamella (LLL), orbital roof fovea to ethmoidal distance (ORFED) and orbital roof to cribriform plate distance (ORCPD) and we determined Keros and LLCPA types from paranasal sinus CT of subjects under 16 years of age retrospectively. RESULTS: The incidence of Keros type I was higher in females and Keros Type II in males. The ORCPD, DOF and LLL values were found to be higher in 13-16 years age group and WOF and LLCPA in 4-6 years age group. The prevalence of Keros type II was higher in the 13-16 age group, and Keros type I was higher in other age groups. LLCPA type A was the most frequent in all age groups and in both sexes. There was a positive correlation between age and ORCPD, DOF, LLL, and a negative correlation with ORFED, WOF, LLCPA. Olfactory fossa width and depth had a negative correlation. LLCPA had a positive correlation with WOF and a negative correlation with DOF. There was a positive correlation between LLCPA and LLL. DOF and LLL had a positive correlation too. CONCLUSIONS: Paranasal sinus CT provides useful information about frontal skull base anatomic relations before sinus surgery in pediatric cases.

The assessment of cognitive functions in patients with isolated cerebellar infarctions: A follow-up study.

The role of the cerebellum on cognitive functions have been well-defined; however, the information related to the progress in time process is limited. In this study, we aimed to evaluate the cognitive function of patients with isolated cerebellar infarction in both the acute stage and the follow-up period. Twenty-three patients with isolated cerebellar infarction and 22 healthy control were examined through an extensive neuropsychological assessment battery. The patients were evaluated in the acute stage and at least six months after the stroke in the follow-up period. There were no significant differences between the patients and the controls regarding age (52.2 ± 7.0 and 54.9 ± 6.6, p = 0.184) and gender (Female/Male: 6/17 and 7/15, p = 0.672). There was no statistically significant difference between patients with right cerebellar infarction and left cerebellar infarction in terms of cognitive functions. Verbal fluency, attention, and verbal and non-verbal episodic memory scores were significantly lower in patient group in the acute stage when compared to the control group. When the follow-up evaluation was compared to acute stage, it was revealed that patients had recovered in all areas; however, less improvement was seen in word reading time. Our results support that lesions of the cerebellum affect cognitive functions in the acute stage. However, the improvement was demonstrated in all cognitive functions in the follow-up period.

Endocan: A Novel Predictor of Endothelial Dysfunction in Silent Brain Infarction.

Silent brain infarction (SBI) has been considered as a subclinical risk factor for symptomatic possible future stroke. We investigated the association between serum inflammatory markers and SBI. Patients (n = 54) diagnosed with SBI as the study group and 52 individuals as the control group were included in this study. Silent brain infarction is defined as a hyperintense lesion that was ≥3 mm in 1 dimension on fluid-attenuated inversion recovery T2-weighted magnetic resonance image, if the patient had normal neurological examination or had an abnormality that was not consistent with the brain lesion locations, after being evaluated by a neurologist. Serum endocan levels (P = .036) and high-sensitivity C-reactive protein (hsCRP; P = .022) were significantly higher in patients with SBI than the controls. Pentraxin 3, erythrocyte sedimentation rate, white blood count, lymphocyte, monocyte, neutrophil, low-density lipoprotein, and triglyceride levels were not significantly different when comparing the groups with and without SBI. There was a significant correlation (r = -0.196; P = .16) between hsCRP and endocan levels in the SBI group. Endocan, a novel biomarker of endothelial pathology, was significantly increased in patients with SBI and may be useful to predict the future risk of stroke.

Wernicke's Encephalopathy: Similar and Different Aspects of the Three Cases.

Wernicke encephalopathy is a neurological disorder, clasically characterized by altered consciousness, ophtalmoparesis, and ataxia results from tiamin deficiency. It is frequently associated with chronic alcohol abuse; however, many conditions which lead to thiamine deficiency such as gastric surgery, hyperemesis, parenteral nutrition, malnutrition may also be the cause. WE is a life-threatening condition that requires early diagnosis and rapid initiation of intravenous thiamin therapy. In patients, findings of characteristic examinations may not always be seen; therefore, imaging methods are of great importance. In this article, we aimed to emphasize the similar and different aspects of three WE cases with typical and atypical imaging findings.

Adenoid cystic carcinoma of the parotid metastasising to the dura fifteen years post primary resection: A case report.

Adenoid cystic carcinoma (ACC), regardless of the primary site, is typically characterized by a long clinical course associated with a high rate of distant metastases. Intracranial metastasis of ACC is a very rare entity with only few reported cases in the literature. In this study, we report an unusual case of extra-axial intracranial metastasis of ACC in the dura. The primary parotid gland tumour was resected 15 y back. No recurrence had been detected before the occurrence of extra-axial metastasis. After surgical decompression, palliative radiotherapy was administered. To our knowledge, this is the longest interval for the development of metastases following excision of a parotid adenoid cystic carcinoma. This case can raise awareness across specialties that patients with adenoid cystic carcinoma are still at risk of developing metastases even following specialist discharge.

Multidetector Computed Tomography Findings of Auto-Evacuated Secondary Acquired Cholesteatoma: A Morphologic and Quantitative Analysis.

OBJECTIVES: To describe and quantify computed tomography (CT) findings of auto-evacuated (spontaneously drained) secondary acquired cholesteatoma (SAC). MATERIALS AND METHODS: This multicenter retrospective study included 69 patients with intermittent ear discharge diagnosed with SAC by autoscopy or automicroscopy who were surgically treated. Three independent radiologists measured the medial and lateral attic distance on coronal and axial planes using multidetector computed tomography (MDCT) in 75 ear CTs from 69 patients with intraoperatively verified diagnoses of pars flaccida cholesteatoma (n=36), pars tensa cholesteatoma (n=24), and auto-atticotomy or automastoidectomy (n=15) and compared them with contralateral healthy ears. RESULTS: A circular or elliptical air-filled cavity surrounded by granulation tissue was morphologically detected on MDCT in these patients. The lateral attic distance was significantly higher in pars flaccida cholesteatoma cases than in contralateral healthy ears on both coronal and axial planes (p<0.05). The medial attic distance was significantly higher in pars tensa cholesteatoma cases than in contralateral healthy ears in the axial pane, but with no difference in the coronal plane. CONCLUSION: In patients with chronic intermittent aural discharge, nonopacified areas surrounded by granulation tissue, which expands the medial or lateral attic in a CT scan, suggest an auto-evacuated cholesteatoma.

A rare condition mimicking stroke: Diabetic uremic encephalopathy.

Uremic encephalopathy (UE) is a metabolic disorder associated with acute or chronic renal failure. It is characterized by the acute or subacute onset of reversible neurological symptoms and specific imaging findings. It is uncommon for uremic encephalopathy to be associated with acute bilateral lesions of the basal ganglia in diabetic uremic patients, and this can be seen most often in Asian patients. Here, we report a patient with diabetic uremic encephalopathy and bilateral basal ganglia lesions who developed acute onset dysarthria. The clinical and magnetic resonance brain imaging findings resolved after hemodialysis treatment.

Neck Muscle Mass Index as a Predictor of Post-Laryngectomy Wound Complications.

OBJECTIVE: We investigated the relationship between paravertebral muscle cross-sectional area (PVM CSA) at the third vertebra (C3) level using computerized tomography (CT) neck images and its relationship with complications after total laryngectomy. DESIGN: Retrospective analysis of 60 advanced laryngeal cancer patients who underwent total laryngectomy was performed. The cross-sectional areas of paravertebral neck muscles using neck CT at C3 level images obtained preoperatively were analyzed. RESULTS: A significant difference in PVM CSA between complication and no complication groups, F(1, 53 = 4.319, P = .043), was identified by ANCOVA. There were no significant differences in between-subject effects: T-stage ( F = 1.652, P = .204), body mass index ( F = 0.889, P = .35), albumin ( F = .359, P = .552), age ( F = 1.623 P = .208), and smoking ( F = 4.319, P = .41). CONCLUSION: The PVM CSA measured at C3 level on pretreatment CT may help identify patients at higher risk of postoperative wound complications after total laryngectomy and who may particularly benefit from preoperative optimization of nutritional status.

Paraganglioma of the larynx diagnosed with maneuvered three-phase contrast-enhanced computed tomography.

The standard diagnostic tool for laryngeal paraganglioma is generally accepted to be magnetic resonance imaging. However, the role of other imaging modalities has not been evaluated extensively. We describe the case of a 38-year-old man who had a history of voice distortion for several years. A hypervascular submucosal lesion was detected on maneuvered three-phase contrast-enhanced computed tomography (CT). The CT showed intense contrast enhancement in the first arterial phase (inspiration), a peak level in the second phase (Valsalva), and washing out in the final phase (phonation). This pattern of contrast enhancement suggested the presence of a hypervascular lesion, such as a hemangioma, paraganglioma, or vascular malformation of the larynx. We conclude that maneuvered three-phase contrast-enhanced CT may be useful for the diagnosis of paraganglioma of the larynx.

Retrospective study of 24 cases of acute appendiceal diverticulitis: CT findings and pathological correlations.

PURPOSE: Appendiceal diverticulitis is relatively rare and is difficult to distinguish clinically and radiologically from acute appendicitis. The aim of this study was to describe the computed tomography (CT) findings of acute appendiceal diverticulitis. MATERIALS AND METHODS: Among the 1329 patients who underwent appendectomy at our institution between January 2010 and July 2015, 28 were diagnosed pathologically with appendiceal diverticulitis, including 24 patients who were evaluated by preoperative CT. The control group consisted of 38 patients without diverticulitis. Average age of patients, ratio of males to females, appendiceal diameter, presence of a diverticulum, diverticular enhancement, peri-appendiceal fat stranding, peri-appendiceal loculated fluid and perforation, and the presence of appendicolith were evaluated retrospectively. RESULTS: Peri-appendiceal fat stranding (p < 0.005), appendiceal diameter (p < 0.005), and peri-appendiceal loculated fluid differed significantly between the diverticulitis and non-diverticulitis groups (p < 0.005). CONCLUSION: Although relatively uncommon, appendiceal diverticulitis should be included in the differential diagnosis of acute appendicitis. It differs from typical acute appendicitis by the presence of an inflamed diverticulum, seen on CT. These patients are also more likely to have peri-appendiceal extra-luminal loculated fluid, peri-appendiceal fat stranding, and a larger diameter of the appendix. The latter finding is likely due to the increased intraluminal pressure.

Anatomic Variations in Paranasal Sinuses of Patients With Sinonasal Polyposis: Radiological Evaluation.

OBJECTIVE: Although sinonasal anatomic variations have been postulated as a risk factor for sinus disease, the role of anatomic abnormalities in the pathogenesis of nasal polyps is still unclear. This study was conducted to examine the association of sinonasal polyposis with anatomic variations. METHODS: The paranasal sinus computerized tomography scans of 155 patients with sinonasal polyposis were examined retrospectively from January 2012 to 2014 in a tertiary care hospital. Paranasal sinus computerized tomography of 100 patients without complaints and signs of sinus disease were also included to serve as control group. The incidence of anatomic variations was evaluated. The sinonasal polyposis and control group data was compared statistically. RESULTS: The incidence of the septal deviation, concha bullosa, Agger nasi, frontal sinus hypoplasiaand accessory sinus ostium in healthy subjects, and sinonasal polyposis patients revealed statistically significant difference. The mentioned variations were found significantly higher in sinonasal polyposis patients (P = 0.000, P = 0.000, P = 0.001, P = 0.002, and P = 0.035 respectively) and may be predisposing for this pathology. CONCLUSION: Considering the results obtained, the presence of septal deviation, concha bullosa, Agger nasi cell, frontal sinus hypoplasiaand accessory sinus ostium may play role in pathogenesis of sinonasal polyposis.

Computed tomographic analysis of frontal sinus drainage pathway variations and frontal rhinosinusitis.

OBJECTIVE: The objective of this study was to radiologically determine frontal sinus drainage pathway variations with respect to superior attachment of uncinate process (SAUP) and their effect on prevalence of frontal rhinosinusitis. DESIGN: This was a retrospective cohort study. METHODS: Computed tomography scans of the 919 frontal sinus sides of 460 patients (252 female, 208 male; mean age, 35.1 ± 10.5 years) who were candidates for endoscopic sinus surgery were evaluated retrospectively between August 2012 and January 2013 by 3 radiologists to determine the SAUP types and the presence of frontal rhinosinusitis. RESULTS: The frontal sinus outflow tract was localized medial to the SAUP in 651 frontal sinus sides and lateral to the SAUP in 268 sides. We determined 3 types (types 7, 8, and 9) of SAUP in addition to 6 types defined in literature. The most common type of SAUP was type 3 (n = 332, 36.1%) followed by type 2 (n = 256, 27.8%) and type 7 (n = 160, 17.4%). Of the evaluated sides, 316 (34.3%) had frontal rhinosinusitis. Frontal rhinosinusitis was more common in the sides where the frontal sinus outflow tract was localized medial to the SAUP than those localized lateral (37.2% vs 27.6%, P = 0.006). CONCLUSIONS: Endoscopic approach to frontal recess usually requires uncinectomy, and it is necessary to know SAUP to prevent postoperative retained superior portion of the uncinate process. The location of frontal sinus outflow tract on the SAUP affects the prevalence of frontal rhinosinusitis as well. Frontal rhinosinusitis is significantly more common when the frontal sinus outflow tract was localized medial rather than lateral to the SAUP. LEVEL OF EVIDENCE: 2b.

Diffusion tensor imaging of cysts, hemangiomas, and metastases of the liver.

BACKGROUND: Although diffusion-weighted magnetic resonance imaging imaging (DW-MRI) is commonly used to characterize hepatic lesions, the literature is sparse about the use of MR diffusion tensor imaging (DTI) in this regard. By using DTI, one is able to obtain not only apparent diffusion coefficients (ADCs) but also fractional anisotropy (Fa) values. PURPOSE: To evaluate DTI using ADC and Fa values in the imaging of hepatic cysts, hemangiomas, and metastases. MATERIAL AND METHODS: Sixty-six patients with 77 lesions were examined with DTI. There were 32 metastases, 13 cysts, and 32 hemangiomas. Two radiologists performed ADC and Fa measurements. Inter-observer agreement was evaluated using Bland-Altman plots. ADCs and Fa values were correlated using Pearson correlation. The differences were compared using ANOVA and Tukey tests. A ROC analysis was applied; sensitivities and specificities were calculated. RESULTS: The inter-observer agreement was very good. The correlation between ADC and Fa was negative, weak, and significant (r = -0.36). The mean ADC value of cysts (3.30 ± 0.8 × 10(-3) mm(2)/s) was significantly higher than that of hemangiomas (2.23 ± 0.5 × 10(-3) mm(2)/s) and metastases (1.62 ± 0.4 × 10(-3) mm(2)/s). The mean Fa value of cysts (0.2 ± 0.05) was significantly lower than hemangiomas (0.37 ± 0.1) and metastases (0.46 ± 0.1). The Az values for discriminating metastases from benign hepatic lesions for ADC and Fa value were 0.885 and 0.731, respectively. The sensitivity and specificity of ADC and Fa were 87.5% and 84.4%, and 78.1% and 57.8%, respectively. The Az value for discriminating cysts from hemangiomas for Fa was 0.96. The sensitivity and specificity were 90.6% and 92.3%, respectively. CONCLUSION: Fa values may play a supportive role in the imaging of liver lesions. Whereas metastases tend to have low ADCs and high Fa values, cysts have high ADCs and low Fa values and hemangiomas have high ADCs and high Fa values.

Reliability of preoperative multidetector computed tomography scan in patients with chronic otitis media.

OBJECTIVE: The objectives of this study were to specify the objective criteria of existence of cholesteatoma in chronic otitis media on the preoperative multidetector computed tomography (MDCT) and to evaluate the complications of disease. METHODS: We compared the results of preoperative MDCT scan with intraoperative findings in 71 patients (22 women, 49 men; mean age, 16-73 years) who had mastoidectomy operation between January 2008 and May 2012. Multidetector computed tomography evaluations of temporal bone were performed on a workstation using high-spatial-resolution magnified images with intended angle and plane. RESULTS: We observed cholesteatoma formation in all patients with scutum erosion (n = 11), dural exposure (n = 6), and lateral semicircular canal fistula (n = 5). Computed tomography revealed these findings with 100% sensitivity. Distortion of ossicular integrity (n = 11) and facial canal dehiscence (n = 5) was significantly higher in cholesteatoma patients. Using the criteria of osteolysis, the sensitivity, specificity, and the accuracy rates of MDCT in detecting cholesteatoma were 71%, 93%, and 88%, respectively. The best diagnostic clue of a cholesteatoma was a mass-like soft tissue located in a retraction pocket in the posterosuperior quadrant of the Shrapnell membrane, causing widening of Prussak space and scutum erosion. Evaluation of computed tomography scan showed nearly 100% sensitivity in detecting tympanic opacification, dural height, dehiscence of lateral semicircular canal, tegmen tympani erosion, and deformation of malleoincudal articulation. However, its contribution to detecting minor ossicular erosion, facial canal dehiscence, and incudostapedial joint evaluation was limited. CONCLUSIONS: Preoperative assessment of chronic otitis media via MDCT with intended angle and plane produces important guidance to understand the extent of disease and to prevent possible intraoperative complications.