[Factors associated with the risk of COVID-19 in health-care workers]. / Factores asociados al riesgo de COVID-19 en el personal de salud.

BACKGROUND: Although healthcare personnel are considered a high-risk group for SARS-CoV-2 infection due to their exposure, research on the factors associated with their infection is limited. The objective was to identify factors associated with the acquisition of COVID-19 in healthcare personnel. METHODS: a multicenter, cross-sectional study with nested cases and controls was carried out in 23 hospitals in Argentina. A structured survey was used to collect demographic, institutional and behavioral variables from healthcare personnel with positive RT-PCR for SARS-CoV2 (cases) and healthcare personnel with negative test results (controls). Those variables significantly associated with the condition of having had COVID-19 in the bivariate analysis were included in a multivariate analysis. RESULTS: A total of 2088 workers participated in the study, with an incidence of 1.41 cases per 10 000 worker-hours (95%CI 1.35-1.48). Being male, (OR 1.60; 95%CI 1.32-1.95), working in social security, (OR 1.53; 95%CI 1.13-2.07), being nursing staff, (OR 1.46; 95%CI 1.22-1.74), having personal protective equipment, (OR 0.33; 95%CI 0.18-0.62), sharing unprotected common spaces with other workers, (OR 1.98; 95%CI 1. 60-2.44), living with people confirmed or suspected of COVID-19 (OR 1.69; 95%CI 1.37-2.09), sharing infusions or other drinks and/or food with people in the community (OR 1.31; 95%CI 1.02-1.70), feeling distressed (OR 1.85; 95%CI 1.55-2.21) and were independently associated with the risk of acquiring COVID-19. DISCUSSION: This study allowed us to identify different potentially modifiable factors on which action should be taken to reduce the risk of acquiring COVID-19 by the healthcare personnel.

Introducción: Aunque, el personal sanitario es considerado por su exposición un grupo de alto riesgo de infección por SARS-CoV-2, la investigación sobre los factores asociados a infección resulta limitada. El objetivo fue identificar los factores asociados a la adquisición de COVID-19 en el personal sanitario. Materiales y métodos: Estudio multicéntrico, de corte transversal con casos y controles anidados, en 23 hospitales de Argentina. A través de una encuesta estructurada se recolectaron variables demográficas, institucionales y conductuales del personal sanitario con RT-PCR positiva para SARS-CoV-2 (casos) y del personal sanitario con resultados negativos en el test (controles). Aquellas variables asociadas significativamente con la condición de haber padecido COVID-19 en el análisis bivariado fueron incluidas en un análisis multivariado. Resultados: Participaron del estudio 2088 trabajadores, con una incidencia de 1.41 casos c/10 000 horas-trabajador (IC95% 1.35-1.48). Pertenecer al sexo masculino (OR 1.60; IC95% 1.32-1.95), trabajar en la seguridad social (OR 1.53; IC95% 1.13-2.07), ser personal de enfermería (OR 1.46; IC95% 1.22-1.74), contar con elementos de protección personal (OR 0.33; IC95% 0.18-0.62), compartir con otros trabajadores espacios comunes sin protección (OR 1.98; IC95% 1.60-2.44), convivir con personas confirmadas o sospechadas de COVID-19 (OR 1.69; IC95% 1.37-2.09), compartir infusiones u otras bebidas y/o alimentos con personas de la comunidad (OR 1.31; IC95% 1.02-1.70), sentirse angustiado (OR 1.85; IC95% 1.55-2.21) se asociaron independientemente con el riesgo de adquirir COVID-19. Discusión: Este estudio permitió identificar distintos factores potencialmente modificables, sobre los cuales se debería actuar para reducir el riesgo de COVID-19 en el personal sanitario.

Factores asociados al riesgo de COVID-19 en el personal de salud / Factors associated with the risk of COVID-19 in health-care workers

Resumen Introducción: Aunque, el personal sanitario es considerado por su exposición un grupo de alto riesgo de infección por SARS-CoV-2, la investigación sobre los factores asociados a infección resulta limitada. El objetivo fue identificar los factores asociados a la adquisición de COVID-19 en el personal sanitario. Materiales y métodos: Estudio multicéntrico, de corte transversal con casos y controles anidados, en 23 hospitales de Argentina. A través de una encuesta estructurada se recolectaron variables demográficas, ins titucionales y conductuales del personal sanitario con RT-PCR positiva para SARS-CoV-2 (casos) y del personal sanitario con resultados negativos en el test (controles). Aquellas variables asociadas significativamente con la condición de haber padecido COVID-19 en el análisis bivariado fueron incluidas en un análisis multivariado. Re sultados: Participaron del estudio 2088 trabajadores, con una incidencia de 1.41 casos c/10 000 horas-trabajador (IC95% 1.35-1.48). Pertenecer al sexo masculino (OR 1.60; IC95% 1.32-1.95), trabajar en la seguridad social (OR 1.53; IC95% 1.13-2.07), ser personal de enfermería (OR 1.46; IC95% 1.22-1.74), contar con elementos de protección personal (OR 0.33; IC95% 0.18-0.62), compartir con otros trabajadores espacios comunes sin protección (OR 1.98; IC95% 1.60-2.44), convivir con personas confirmadas o sospechadas de COVID-19 (OR 1.69; IC95% 1.37-2.09), compartir infusiones u otras bebidas y/o alimentos con personas de la comunidad (OR 1.31; IC95% 1.02-1.70), sentirse angustiado (OR 1.85; IC95% 1.55-2.21) se asociaron independientemente con el riesgo de adquirir COVID-19. Discusión: Este estudio permitió identificar distintos factores potencialmente modificables, sobre los cuales se debería actuar para reducir el riesgo de COVID-19 en el personal sanitario.

Abstract Background: Although healthcare personnel are considered a high-risk group for SARS-CoV-2 infection due to their exposure, research on the factors associated with their infection is limited. The objec tive was to identify factors associated with the acquisition of COVID-19 in healthcare personnel. Methods: a multicenter, cross-sectional study with nested cases and controls was carried out in 23 hospitals in Argentina. A structured survey was used to collect demographic, institutional and behavioral variables from healthcare personnel with positive RT-PCR for SARS-CoV2 (cases) and healthcare personnel with negative test results (controls). Those variables significantly associated with the condition of having had COVID-19 in the bivariate analysis were included in a multivariate analysis. Results: A total of 2088 workers participated in the study, with an incidence of 1.41 cases per 10 000 worker-hours (95%CI 1.35-1.48). Being male, (OR 1.60; 95%CI 1.32-1.95), working in social security, (OR 1.53; 95%CI 1.13-2.07), being nursing staff, (OR 1.46; 95%CI 1.22- 1.74), having personal protective equipment, (OR 0.33; 95%CI 0.18-0.62), sharing unprotected common spaces with other workers, (OR 1.98; 95%CI 1. 60-2.44), living with people confirmed or suspected of COVID-19 (OR 1.69; 95%CI 1.37-2.09), sharing infusions or other drinks and/or food with people in the community (OR 1.31; 95%CI 1.02-1.70), feeling distressed (OR 1.85; 95%CI 1.55-2.21) and were independently associated with the risk of acquiring COVID-19. Discussion: This study allowed us to identify different potentially modifiable fac tors on which action should be taken to reduce the risk of acquiring COVID-19 by the healthcare personnel.

Molecular epidemiology of Acinetobacter baumannii spread in an adult intensive care unit under an endemic setting.

BACKGROUND: Acinetobacter baumannii (Ab) clones I, III, and IV were recovered in several Buenos Aires City hospitals. We investigated the prevalence of these clones with epidemic behavior (EB) in our intensive care unit (ICU) under an endemic setting and its spread. METHODS: A 10-week prospective cohort study including surveillance cultures of newly admitted patients was conducted. Air, environment, and staff hands were weekly screened. In the seventh week, a new environmental cleaning protocol and a staff hand hygiene reeducation program were implemented. RESULTS: Almost 15% of all screening samples (159/1042) were Ab positive. Up to the seventh week, carbapenem-resistant clone If was the main one recovered from patients, environmental frequently touched surfaces (EFTS), and staff hands screening samples. Few air samples were Ab positive. Clone I was also isolated from patients at admission. After the seventh week, a significant reduction of EFTS contamination and of clone If isolation was observed. During the last 3 weeks, clone I was no longer isolated from patients. Instead, the newly identified clone IVb was mainly cross transmitted. It was also recovered from staff hands and from EFTS. In the last week, clone If was again isolated from 1 bed rail. CONCLUSION: Patients with EB clones-positive culture at admission provide verification that interhospital patient transfers play a role in these clones spread. However, subtypes such as clone If seem to be endemic in our ICU. EFTS showed to have potential for EB clones transmission via transient staff hand carriage. Transmission did not involve airborne route.

Prevención de infecciones asociadas a catéteres vasculares

La autora describe en este artículo la microbiología, epidemiología y patogénesis de las infecciones asociadas a catéteres vasculares. Asimismo describe algunas recomendaciones para reducir las bacteriemias primarias.

Identification of an epidemic carbapenem-resistant Acinetobacter baumannii strain at hospitals in Buenos Aires City.

To identify epidemic Acinetobacter baumannii (AB) clones, 38 carbapenem-resistant AB isolates from 5 hospitals were analyzed. Macrorestriction classified 24 isolates as clone IV, susceptibility pattern clustering analysis grouped almost all of them together, and they were uniformly biotype 8. Clone IV was present at all 5 hospitals, so that it represents a carbapenem-resistant AB strain with epidemic behavior.