Cardiorespiratory fitness associates negatively with arterial stiffness in a cohort of industrial workers followed up for 4 years.

OBJECTIVE: Previously we have found increased carotid-to-femoral pulse wave velocity (cfPWV) among shift workers compared to day workers in industry, and a decline in maximal oxygen uptake (V̇O2max) in all 86 workers. METHODS: Utilizing all available measurements in 2018, 2021 and 2022, this study investigated associations between V̇O2max and measures of arterial stiffness. Using a mixed model approach, we analysed the cross-sectional association between all V̇O2max (outcome) and measures of arterial stiffness (covariates). RESULTS: We observed a significant association between V̇O2max and cfPWV of -1.59 (95%CI -3.03, -0.16), augmentation pressure (AP) and augmentation index (Aix) of -0.32 (95%CI -0.58, -0.06) and -0.12 (95%CI -0.23, -0.005), respectively. CONCLUSIONS: We found a significant negative association between cardiorespiratory fitness and measures of arterial stiffness. The former and present results pose challenges for shift workers' future macro and microvascular health.

The association between psychological distress and alcohol consumption and physical activity: a population-based cohort study.

Introduction: The COVID-19 pandemic and infection control measures caused changes to daily life for most people. Heavy alcohol consumption and physical inactivity are two important behavioral risk factors for noncommunicable diseases worldwide. The COVID-19 pandemic, with its social distancing measures, home office policies, isolation, and quarantine requirements may have an impact on these factors. This three-wave longitudinal study aims to investigate if psychological distress and worries related to health and economy were associated with levels and changes in alcohol consumption and physical activity during the two first years of the COVID-19 pandemic in Norway. Methods: We used data collected in April 2020, January 2021, and January 2022 from an online longitudinal population-based survey. Alcohol consumption and physical activity status were assessed at all three measuring points via the Alcohol Use Disorder Identification Test (AUDIT-C) and the International Physical Activity Questionnaire (IPAQ-SF). COVID-19-related worries, home office/study, occupational situation, age, gender, children below 18 years living at home, and psychological distress (measured with the Symptom Checklist (SCL-10)) were included as independent variables in the model. A mixed model regression was used and presented with coefficients with 95% confidence intervals (CI). Results: Analysis of data from 25,708 participants demonstrates that participants with substantial symptoms of psychological distress more often reported higher alcohol consumption (1.86 units/week, CI 1.48-2.24) and lower levels of physical activity [-1,043 Metabolic Equivalents of Task (METs) per week, CI -1,257;-828] at baseline. Working/studying from home (0.37 units/week, CI 0.24-0.50) and being male (1.57 units/week, CI 1.45-1.69) were associated with higher alcohol consumption. Working/studying from home (-536 METs/week, CI -609;-463), and being older than 70 years (-503 METs/week, CI -650;-355) were related to lower levels of physical activity. The differences in activity levels between those with the highest and lowest levels of psychological distress reduced over time (239 METs/week, CI 67;412), and similarly the differences in alcohol intake reduced over time among those having and not having children < 18 years (0.10 units/week, CI 0.01-0.19). Conclusion: These findings highlight the substantial increases in risks related to inactivity and alcohol consumption among those with high levels of psychological distress symptoms, and particularly during the COVID-19 pandemic, and increase the understanding of factors associated with worries and health behavior.

Influence of Shift Work on Arterial Stiffness and Systemic Inflammation: A 3-Year Follow-up Study in Industry.

OBJECTIVE: To assess changes in cardiovascular disease risk factors during a 3-year follow-up among 57 rotating shift workers and 29 day workers in industry. METHODS: We collected demographics by questionnaire, examined blood pressure, heart rate, pulse wave velocity, carotid media thickness, and maximal oxygen uptake. We assessed blood samples for determination of lipids, glycosylated hemoglobin, C-reactive protein, markers of inflammation, and particle concentrations/respirable dust. Baseline comparisons were analyzed using logistic regression (plaque) and linear regression for all other outcomes. We applied mixed models to assess differences in change in health outcomes between the shift workers and the day workers. RESULTS: At baseline, the adhesion molecules soluble vascular cell adhesion molecule 1 and soluble P-selectin were elevated among the shift workers compared with that of the day workers. There was a significant difference in change in pulse wave velocity between shift workers (1.29-m/s increase) and day workers (0.11-m/s increase) over the 3-year follow-up. Respirable dust levels were below the Norwegian occupational exposure limit. CONCLUSIONS: Shift work in industry is associated with arterial stiffening reflecting increased risk for future cardiovascular disease. More uncertainly, we found some support for systemic inflammation.

The COVID-19 Pandemic Decreases Cardiorespiratory Fitness: A 3-Year Follow-Up Study in Industry.

BACKGROUND: We aimed to determine if maximal oxygen uptake (V˙O2max), resting heart rate (RHR), and self-reported leisure- time moderate to vigorous physical activity (MVPA) changed over a 3-year follow-up (FU) among industrial workers. METHODS: We assessed cardiorespiratory fitness (CRF) August 2018 and August 2021. The last 17-18 months coincided with the COVID-19 pandemic. Data from 86 participants were collected; demographics by questionnaire and cardiovascular outcomes from medical examination: V˙O2max, RHR, and fat mass (%). Workers reported on their leisure-time MVPA twice. To assess changes in health outcomes we applied a linear mixed model, adjusting for baseline (BL) age, sex, pack-years, shift work, and a 5-month plant shutdown. Further, we adjusted for actual age instead of BL age. RESULTS: V˙O2max decreased from 39.6 mL/kg/min at BL to 34.0 at FU, a reduction of 5.6 mL/kg/min (95%CI, -7.6, -3.7). Adjusted for actual age, the corresponding figure for V˙O2max was 5.4 mL/kg/min, (95%CI, -7.4, -3.4), an annual loss of 4.6%. RHR increased from 61.3 to 64.4 beats per minute (95%CI, 0.8, 5.4). Self-reported MVPA decreased by 43.9 min/week, (95%CI, -73.5, -14.4). CONCLUSIONS: We observed a decrease in V˙O2max, an increase in RHR and a decrease in self-reported MVPA, suggesting physical inactivity during the COVID-19 pandemic.

Increase in peak oxygen uptake and Andersen test performance in children from age six to ten: The Health Oriented Pedagogical Project (HOPP).

The increased prevalence of non-communicable disease risk factors among children because of lack of physical activity is concerning. The Health Oriented Pedagogical Project was set up to combine learning activities and physical activity, thus reducing sedentariness during school time. The current study aimed to measure and describe the longitudinal and cross-sectional development of oxygen uptake and running performance in children at ages six and ten. The validity of the Andersen Test in predicting V̇O2peak in these age groups was also evaluated. Eighty-six children (53 boys, 33 girls) with complete datasets at ages 6 and 10 years were included in the longitudinal study, while 192 children (106 boys, 86 girls) were included in the cross-sectional analysis because they missed data from 1 year. Oxygen uptake was measured using a metabolic analyser and maximal treadmill running, while the distance covered during the AT determined running performance. Body mass, height, and waist-to-height ratios were recorded. Multiple regression analysis was used to assess the association between oxygen uptake and running performance. The cross-sectional results did not differ from the longitudinal data for anthropometrical data, oxygen uptake and running performance. Height, body mass and waist-to-height ratio did not differ between the sexes at ages six or ten. Boys had significantly higher peak oxygen uptake than girls at 6 years of age, irrespective of how oxygen uptake was expressed. Allometric scaling of oxygen uptake revealed differences between sexes at both ages. Longitudinal running performance increased in both sexes from 6 to 10 years. Boys ran significantly longer only at age ten. The association between oxygen uptake and running performance varied according to how the oxygen uptake was expressed and with sex and age. Ten-year-old girls had the highest correlations in the longitudinal investigation, from r 2 = 0.48 (fV̇O2peak) to 0.65 (rV̇O2peak) between AT and V̇O2peak. The AT was found to be as valid as the 20-m shuttle run test in estimating peak oxygen uptake, with a random measurement error of approximately 11% of mean values.

A holistic perspective on continuing care for substance use and dependence: Results and implications from an in-depth study of a Norwegian continuing care establishment.

This article explores, systematically and in depth, users' perceptions of participating in a Norwegian non-profit establishment that provides a continuing care programme for substance use and dependence. Identified results are linked to a holistic system perspective, where human, technology, and organisation (HTO), as well as external environment, are viewed as intertwined. At the establishment level, i.e., where the continuing care programme is delivered, we find that a clear holistic and user-oriented profile - comprising combined interventions including physical and social activities - can create a safe and stable environment that exerts a positive mental and physical influence on the user and thereby promotes abstinence from substances. However, our results suggest that the internal environment needs to connect more strongly with the external environment, such as a substance-free network, close family, and working life. At the establishment level, we conclude that there is a need to develop an explicit strategy and practice for collaborating with the external environment, built on systemisation and application of individual users' insights into the design of the current interventions. Further research should explore the presence and absence of interplays between elements of human, technology, and organisation and the external environment, and the associated consequences for intervention processes and users' health outcomes. Our holistic system model, empirically informed by data from a Norwegian context, can represent a starting point for such endeavours. The holistic system model also constitutes an original and novel contribution to research on continuing care interventions.

Blood Pressure Response and Pulse Arrival Time During Exercise Testing in Well-Trained Individuals.

Introduction: There is a lack of data describing the blood pressure response (BPR) in well-trained individuals. In addition, continuous bio-signal measurements are increasingly investigated to overcome the limitations of intermittent cuff-based BP measurements during exercise testing. Thus, the present study aimed to assess the BPR in well-trained individuals during a cycle ergometer test with a particular focus on the systolic BP (SBP) and to investigate pulse arrival time (PAT) as a continuous surrogate for SBP during exercise testing. Materials and Methods: Eighteen well-trained male cyclists were included (32.4 ± 9.4 years; maximal oxygen uptake 63 ± 10 ml/min/kg) and performed a stepwise lactate threshold test with 5-minute stages, followed by a continuous test to voluntary exhaustion with 1-min increments when cycling on an ergometer. BP was measured with a standard automated exercise BP cuff. PAT was measured continuously with a non-invasive physiological measurements device (IsenseU) and metabolic consumption was measured continuously during both tests. Results: At lactate threshold (281 ± 56 W) and maximal intensity test (403 ± 61 W), SBP increased from resting values of 136 ± 9 mmHg to maximal values of 219 ± 21 mmHg and 231 ± 18 mmHg, respectively. Linear within-participant regression lines between PAT and SBP showed a mean r 2 of 0.81 ± 17. Conclusion: In the present study focusing on the BPR in well-trained individuals, we observed a more exaggerated systolic BPR than in comparable recent studies. Future research should follow up on these findings to clarify the clinical implications of the high BPR in well-trained individuals. In addition, PAT showed strong intra-individual associations, indicating potential use as a surrogate SBP measurement during exercise testing.

The Role of Physical Activity in Opioid Substitution Therapy: A Systematic Review of Interventional and Observational Studies.

Background: Use of physical activity in the treatment and follow-up of people receiving opioid substitution therapy is an understudied area of research. Therefore, the objective of this systematic review was to synthesize the currently available research on the role of physical activity in opioid substitution therapy and proper adaptions for the group. Methods: A systematic search was performed on PsycINFO, EMBASE, MEDLINE, CINAHL, and Web of Science until September 2021 (PROSPERO-reg.no: CRD42020109873). The inclusion criteria were studies involving physical activity interventions for opioid substitution patients. Reference lists of relevant studies were screened to identify additional relevant studies. Data extracted were compiled into tables and descriptively presented. Results: The search yielded 2105 unique records. A total of 10 studies were included, whose methodological quality ranged from satisfactory to very good. Study quality was assessed using a 7-/8-point quality score. The agreement between the reviewers, assessed with Cohen's kappa, was 0.91. Overall, the results suggest that physical activity increases physical fitness of patients in opioid substitution therapy and decreases substance use. The minority of studies in this field are of high quality with sufficient power. Conclusions: The findings of this systematic review suggest beneficial effects of physical activity on physical fitness, substance use, and mental health for patients in opioid substitution therapy. Although the findings are quite consistent across studies, high-quality studies and sufficiently powered clinical trials are needed to confirm and validate the findings and to conclude on the degree of impact.

Examination of a new functional firefighter fitness test.

Firefighters must meet certain physical requirements. This study compares the demands of a new firefighting-specific tasks test with an existing laboratory test. Thirty-five male subjects were tested. In both tests, the subjects wore a complete firefighting outfit including breathing apparatus, but not the usual facemask. Test durations were 8 min (existing test) vs ≈10 min (new test). Peak oxygen uptake was similar in the tests, ≈45 ml · kg-1 min-1. The time with an oxygen uptake above 35 ml kg-1 min-1 was longer in the new test, 6.4 vs 4.7 min. The results suggest that the new test is as demanding as the traditional test and offers the advantages of being more specific. The new test could therefore serve as an alternative to the existing test. Based on regression analysis of the two tests, a pass/fail time of 10 min 30 s is suggested.

Daily and Weekly Variation in Children's Physical Activity in Norway: A Cross-Sectional Study of The Health Oriented Pedagogical Project (HOPP).

Background The purpose of the study was to examine differences in objectively measured moderate-to-vigorous physical activity (MVPA min/day) and sedentary time (SED min/day) between different time domains as school hours, leisure time, and weekends. An additional objective addressed causal association between body mass and MVPA. METHODS: The study sample consisted of 2015 subjects (51% girls) aged 6-12 years (9.46 ± 1.76) from the Health Oriented Pedagogical Project (HOPP) in south-east Norway. Six days of MVPA min/day and SED min/day were measured using accelerometers and presented as daily averages. The differences in physical activity (PA) were investigated between the time domains of school-hours, leisure time and weekends by age and sex. Data were analyzed using one-and two-way ANOVA. RESULTS: The relative contribution of the different time domains in overall PA was found. Daily average of MVPA min/day and SED min/day differed significantly across the three time domains. The average weekend SED was 56 ± 3.45 and 82 ± 4.12 min/day less when compared with school hours and leisure time, respectively. On average children spent 27 ± 2.74 min/day less in MVPA during school hours, compared with leisure time (p < 0.001), and spent by 38 ± 2.10 min/day more during weekends compared to school hours (p < 0.001). Boys were more physically active than girls, and less time was spent in MVPA with age. CONCLUSION: With the objective of increasing PA in a child population, the findings indicate that PA intervention programs should target children with higher body mass, girls more than boys, older children more than younger, and during school hours and leisure time more than on weekends.

High-Intensity Training Reduces CVD Risk Factors among Rotating Shift Workers: An Eight-Week Intervention in Industry.

Rotating shift work is associated with risk factors for cardiovascular disease (CVD). We have studied the effect of 17 min high-intensity training three times a week over eight weeks on CVD risk factors among shift workers. Sixty-five shift workers from two plants were recruited. They were all deemed healthy at the initial health screening and in 100% work. From plant A, 42 workers, and plant B, 23 workers participated. After the intervention, 56 workers were retested. The intervention group consisted of 19 participants from plant A who had participated in at least 10 sessions. Twenty workers from plant B and 17 workers from plant A that not had taken part in the training were included in the control group. All workers reported physical activity (PA) by questionnaires before and after the training intervention. We measured blood pressure, heart rate, lipids, glycated hemoglobin (HbA1c), and C-reactive protein (CRP) and arterial stiffness. Maximal oxygen uptake (V̇O2max) was assessed by bicycle ergometry. The intervention group favorably differed significantly from the control group in improvement of systolic and diastolic blood pressure and glycated hemoglobin (HbA1c). Short training sessions with 4 min of high-intensity PA, three times a week, for eight weeks among rotating shift workers reduced some CVD risk factors. PA interventions in occupational settings may thus decrease coronary heart disease and stroke incidences in this vulnerable group of workers.

Presenting Health Status in Children Using a Radar Plot.

BACKGROUND: To try out the feasibility of presenting the health status of children 6 to 12 years old by using radar plots. METHODS: With data from the Health Oriented Pedagogical Project (HOPP) we have described the health status for 1340 children aged 6 to 12 years. We collected or calculated: stature, body mass, waist circumference, waist to height ratio, high density lipoprotein (HDL) and total cholesterol concentration, blood pressure, accelerometer assessed physical activity, endurance interval running performance, and quality of life. Pertinent variables were presented through a radar plot for both individual cases and groups. RESULTS: The boys showed better endurance and recorded more moderate to vigorous physical activity than the girls. The activity level dropped from age 6 to age 12 for both sexes. The girls showed a lower systolic blood pressure compared with boys. Self-rated quality of life was high among boys and girls. CONCLUSIONS: This cohort showed good health and the radar plot made it easy to visualise health status for groups and individuals.

Cardiovascular Health Effects of Shift Work with Long Working Hours and Night Shifts: Study Protocol for a Three-Year Prospective Follow-Up Study on Industrial Workers.

There is a plausible association between shift work and cardiovascular disease (CVD), which may be due to disruption of the circadian rhythm causing hormonal changes and metabolic disturbances, resulting in high blood pressure, atherosclerosis, diabetes, and being overweight. However, few studies have investigated the association between several consecutive long work shifts, including night shifts, and risk factors for developing CVD. Moreover, knowledge is lacking on factors that may modify or enhance this suggested relationship. The study period is planned from the third quarter of 2018 to the fourth quarter of 2021, and will involve 125 industrial employees at two Norwegian enterprises producing insulation. The work schedule is either rotating shiftwork (morning, evening, night) or regular day work. At baseline, we will measure blood parameters, including markers of inflammation, lipids, and glycosylated hemoglobin. We will also collect measures of blood pressure, resting heart rate, arterial stiffness, carotid intima-media thickness, and aerobic fitness. At the end of baseline data collection, a subgroup will undergo a supervised high-intensity interval training intervention for eight weeks, initiated by the Occupational Health Service. At one-year follow-up, we repeat baseline measures with added measures of heart rate variability and additional five weeks monitoring of sleep and physical activity, and assessment of respirable dust. At the two year follow-up, we will measure CVD risk factors before and after a planned three-month shutdown in one of the studied plants. We will also assess respirable dust, monitor sleep, and compile a one-year retrospective detailed overview of working hours. A final data collection, similar to the one at baseline, will be carried out after three years. We will use a comprehensive set of methods to identify the effects of shift work with long working hours and night shifts on cardiovascular health. This will provide new knowledge on the association between early manifestations of CVD and occupational exposure to shift work. Further, we can study whether work organization such as extensive overtime, sleep loss, and dust exposure have detrimental effects, and if a three-month cease in shift work or increased physical activity will modify early manifestations of CVD.

The Weather Impact on Physical Activity of 6-12 Year Old Children: A Clustered Study of the Health Oriented Pedagogical Project (HOPP).

It is commonly known that children do not engage in a sufficient amount of physical activity. Weather conditions and day length may influence physical activity of children. Little is known about the relationship between physical activity and seasons. The purpose of this study was to investigate the relationships between weather conditions and physical activity in 6-12 year old children based on hip-worn Actigraph wGT3X-BT accelerometer data. The study sample consisted of 2015 subjects aged 6-12 years from the Health Oriented Pedagogical Project (HOPP) study carried out in Horten municipality and Akershus county, Norway. Six days of sedentary and moderate-to-vigorous physical activity data was gathered in January-June and September-October, 2015, presented as daily averages. The accelerometer-monitored physical activity of children grouped within nine schools was matched with regional weather conditions and assessed with the means of linear mixed models. Increased day length was associated with decreased sedentary behavior. Warmer temperature and dry weather were associated with increased moderate-to-vigorous physical activity after adjusting for age and sex. One-hour increase in daylight resulted in a decrease of sedentary time by, on average, 2 min (95% CI = (-2.577, -0.798)). For every 5 °C increase in temperature (range: -0.95 and 15.51 °C) and dry weather, average moderate-to vigorous physical activity increased by 72 and 67 min (males and females, respectively) (p < 0.001). Days with precipitation had, on average, 10 fewer minutes of moderate-to-vigorous physical activity compared with days without precipitation (95% CI = (-16.704, -3.259)). Higher temperatures and dry weather led to higher physical activity levels, seeing larger increases among boys than girls. A school-based physical activity intervention program should be adjusted regarding local weather conditions in line with the present findings.

The steady-state load of five firefighting tasks.

Purpose. Physiologic demands of five common tasks in firefighting have been examined. Methods. Eight male volunteers, dressed up as smoke divers (+21 kg extra load), carried out the following tasks at constant pace for 5 min: walking at 1.4 m·s-1, walking (all walks at the same speed) while carrying a 10-kg ladder, walking carrying two hose packs of 16 kg together, walking carrying a 32-kg spreader tool and, finally, climbing up and down a ladder at a preset pace. A 5-min break separated each exercise. The heart rate, oxygen uptake and lung ventilation were measured continuously, and the blood lactate concentration was recorded after each task. Results. The end-exercise heart rate rose from 108 to 180 bpm from the first to last task, blood lactate concentration rose from 1 to 7 mmol·L-1, oxygen uptake rose from 19 to 48 ml·kg-1 min-1 and lung ventilation rose from 38 to 124 L·min-1. Discussion. Walking was an easy task even when dressed up as a smoke diver. Adding loads increased demands; ladder climbing taxed >90% of the subjects' aerobic power. Conclusions. The physiologic demands varied considerably between different tasks.

Reliability and Structural Validity of the Movement Assessment Battery for Children-2 in Croatian Preschool Children.

Monitoring and assessment of the development of motor skills is an important goal for practitioners in many disciplines as well as researchers interested in motor development. A well-established tool for such purpose is the Movement Assessment Battery for Children Second Edition (MABC-2) which covers three age ranges and contains eight motor items in each range related to the manual dexterity, aiming and catching, and balance. The main aim of the study was to investigate the reliability and validity of the MABC-2 age band one in a sample of Croatian preschool children. Structural validity was assessed using confirmatory factor analysis (CFA). Measures of relative and absolute reliability were established by computing the intraclass correlation coefficients (ICC), standard error of the measurement (SEM), and smallest detectable change (SDC). About 17% of the children of the total sample fall into the categories of motor impairment and risk for impairment, respectively, while 83% were found to be in the category of normally developing children. Intraclass correlation coefficient for the total standard score was 0.79 while individual items, all except one, ranged from 0.70 to 0.83. Drawing trail, but also throwing beanbag and one-leg balance items presented large SEM and SDC values. CFA initially yielded a model with questionable fit to the data. After re-specification, excellent model fit was attained confirming the proposed three-factor model. Satorra-Bentler χ2(26) reached 38.56 (p = 0.054), root mean square error of approximation (RMSEA) was 0.028, non-normed fit index (NNFI) was 0.98, adjusted goodness of fit (AGFI) was 0.97, and standardized root mean residual (SRMR) was 0.030. All the variables loaded significantly, and only two significant standardized residuals have been found. Correlations between the factors were weak, supporting discriminant validity of the test. We found MABC-2 to be an appropriate instrument to assess the development of motor competences of preschool children.

A Comparative Study of Fitness Levels among Norwegian Youth in 1988 and 2001.

We compared the fitness levels of cohorts of 15-year-old youth in 1988 and 2001 to ascertain whether there was a negative trend in fitness. The subjects were 15-year-old boys and girls from the same geographical area, n = 192 in 1988 and n = 191 in 2001. They participated voluntarily and could leave the project whenever they wished. The following variables were used to assess fitness: Maximal oxygen uptake, jump height, shoulder flexibility, and hamstring flexibility. Maximal oxygen uptake was estimated with submaximal ergometer cycling, jump height by the Sargent jump-and-reach test, shoulder flexibility as the distance between thumbs when doing straight-arm backwards circling while holding a broomstick, and hamstring flexibility by an active straight-leg-raise test. Differences between groups and quartiles were analyzed by Gosset's (Student's) t-test, using a significance level of 0.05. The two cohorts did show different levels of physical fitness. The 1988 group was 3.9 cm better on jump height and 4.2 cm better on shoulder flexibility, while the 2001 group had 3.3° better hamstring flexibility. The lowest performing quartile did less well in 2001 on oxygen uptake and jump height. We recommend an increased focus on improving fitness in low-performing adolescents.

Shift Work Including Night Work and Long Working Hours in Industrial Plants Increases the Risk of Atherosclerosis.

There is an abundance of literature reporting an association between shift work and cardiovascular disease (CVD). Few studies have examined early manifestation of CVD using advanced modern methodology. We established a group of 65 shift workers and 29 day workers (controls) in two industrial plants. For the shift workers, the shift schedule includes rotating shifts with day, evening and nightshifts, some day and nightshifts lasting for 12 h. The current paper describes cross-sectional data in a study running for three years. We collected background data by questionnaire and measured blood pressure, heart rate, lipids, glycosylated hemoglobin (HbA1c) and C-reactive protein (CRP). We examined arterial stiffness (central blood pressure, augmentation pressure and index, and pulse wave velocity) by the use of SphygmoCor® (AtCor Medical Pty Ltd, Sydney, Australia) and the carotid arteries by ultrasound. We assessed VO2max by bicycle ergometry. We applied linear and logistic regression to evaluate associations between total number of years in shift work and cardiovascular outcome measures. The day workers were older and had more pronounced arterial stiffness compared to the shift workers. Number of years as a shift worker was associated with increased carotid intima media thickness (max IMT) (B = 0.015, p = 0.009) and an elevated CRP (B = 0.06, p = 0.03). Within the normal range for this age group, VO2max was 41 (9) ml/kg/min. Rotating shift work including day and night shifts lasting up to 12 h and evening shifts are associated with CVD-risk factors. This could imply an increased risk for coronary heart disease and stroke among these workers. Therefore, preventive measures should be considered for these groups of workers in order to prevent such diseases.