1.
J Org Chem
; 87(5): 3762-3769, 2022 Mar 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35168325
RESUMO
A convenient and practical hydrosulfonylation and disulfonylation of substituted maleimides was realized using sulfonyl hydrazides as the sulfur reagent and tert-butyl hydroperoxide as the oxidant. The advantages of the reactions include mild and transition-metal-free reaction conditions, good functional group tolerance, and readily available starting materials. The radical species-induced pathway is also demonstrated by mechanistic studies.