1.
Angew Chem Int Ed Engl
; 62(24): e202302844, 2023 Jun 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37022339
RESUMO
A peroxygenase-catalysed hydroxylation of organosilanes is reported. The recombinant peroxygenase from Agrocybe aegerita (AaeUPO) enabled efficient conversion of a broad range of silane starting materials in attractive productivities (up to 300â mM h-1 ), catalyst performance (up to 84â s-1 and more than 120 000 catalytic turnovers). Molecular modelling of the enzyme-substrate interaction puts a basis for the mechanistic understanding of AaeUPO selectivity.